ES8300667A1 - Mejoras introducidas en un procedimiento de preparacion de un bifenil-2-carboxaldehido - Google Patents

Mejoras introducidas en un procedimiento de preparacion de un bifenil-2-carboxaldehido

Info

Publication number
ES8300667A1
ES8300667A1 ES501243A ES501243A ES8300667A1 ES 8300667 A1 ES8300667 A1 ES 8300667A1 ES 501243 A ES501243 A ES 501243A ES 501243 A ES501243 A ES 501243A ES 8300667 A1 ES8300667 A1 ES 8300667A1
Authority
ES
Spain
Prior art keywords
carboxaldehydes
substituted
preparing
substituted biphenyl
biphenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES501243A
Other languages
English (en)
Other versions
ES501243A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of ES8300667A1 publication Critical patent/ES8300667A1/es
Publication of ES501243A0 publication Critical patent/ES501243A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/006—Palladium compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
    • C07C45/516—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of nitrogen-containing compounds to >C = O groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00—Compounds having —CHO groups
    • C07C47/20—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms
    • C07C47/24—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00—Compounds having —CHO groups
    • C07C47/52—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
    • C07C47/55—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE BIFENIL-2-CARBOXALDEHIDOS DE FORMULA (I), EN LA QUE A, B, X E Y PUEDEN SER VARIOS TIPOS DE RADICALES. CONSISTE EN LA REACCION DE UN COMPLEJO DE PALADIO DE FORMULA (II), CON UN REACTIVO DE GRIGNARD DE FORMULA (III), O CON EL CORRESPONDIENT FENILLITIO SUSTITUIDO, EN LAS QUE AR ES UN RADICAL ARILO; D ES UN ANION; Y LOS DEMAS SIMBOLOS TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I). LA REACCION SE LLEVA A CABO EN PRESENCIA DE 6 A 8 EQUIVALENTES MOLARES DE TRIFENILFOSFINA. >ESTOS COMPUESTOS TIENEN APLICACIONES COMO INTERMEDIOS EN LA OBTENCIO DE INHIBIDORES SINTETICOS DE LA SINTESIS DE COLESTEROL IN VIVO.
ES501243A 1980-04-14 1981-04-10 Mejoras introducidas en un procedimiento de preparacion de un bifenil-2-carboxaldehido Granted ES501243A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US14032180A 1980-04-14 1980-04-14

Publications (2)

Publication Number Publication Date
ES8300667A1 true ES8300667A1 (es) 1982-11-01
ES501243A0 ES501243A0 (es) 1982-11-01

Family

ID=22490714

Family Applications (1)

Application Number Title Priority Date Filing Date
ES501243A Granted ES501243A0 (es) 1980-04-14 1981-04-10 Mejoras introducidas en un procedimiento de preparacion de un bifenil-2-carboxaldehido

Country Status (9)

Country Link
EP (1) EP0038061B1 (es)
JP (1) JPS56161343A (es)
AT (1) ATE11401T1 (es)
DE (1) DE3168434D1 (es)
DK (1) DK167481A (es)
ES (1) ES501243A0 (es)
GR (1) GR75192B (es)
IE (1) IE51219B1 (es)
PT (1) PT72801B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4613610A (en) * 1984-06-22 1986-09-23 Sandoz Pharmaceuticals Corp. Cholesterol biosynthesis inhibiting pyrazole analogs of mevalonolactone and its derivatives
US4804679A (en) * 1984-07-24 1989-02-14 Sandoz Pharm. Corp. Erythro-(E)-7-(3'-C1-3alkyl-1'-(3",5"-dimethylphenyl)naphth-2'-yl)-3,5-dihydroxyhept-6-enoic acids and derivatives thereof
US4686237A (en) * 1984-07-24 1987-08-11 Sandoz Pharmaceuticals Corp. Erythro-(E)-7-[3'-C1-3 alkyl-1'-(3",5"-dimethylphenyl)naphth-2'-yl]-3,5-dihydroxyhept-6-enoic acids and derivatives thereof
US4668794A (en) * 1985-05-22 1987-05-26 Sandoz Pharm. Corp. Intermediate imidazole acrolein analogs
US6297405B1 (en) * 2000-09-01 2001-10-02 Milliken & Company Fluorinated and chlorinated benzaldehydes
EP2342179B8 (en) 2008-09-11 2015-07-01 Semmelweis Egyetem Compounds for inhibiting semicarbazide-sensitive amine oxidase (ssao) / vascular adhesion protein-1 (vap-1) and uses thereof for treatment and prevention of diseases
CN115092909B (zh) * 2022-07-12 2023-06-09 中南大学 一种高浓度氟掺杂的碳点及其制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1156776B (de) * 1959-04-24 1963-11-07 United States Steel Corp Verfahren zur Herstellung von 2, 2'-Diphenyldicarboxaldehyd
GB1499655A (en) * 1974-01-31 1978-02-01 Allen & Hanburys Ltd Biphenyl derivatives
DE2801887A1 (de) * 1977-12-20 1979-06-21 Bbc Brown Boveri & Cie Verfahren zur herstellung von p-substituierten benzaldehyden

Also Published As

Publication number Publication date
EP0038061A1 (en) 1981-10-21
DE3168434D1 (en) 1985-03-07
PT72801B (en) 1983-01-10
JPS56161343A (en) 1981-12-11
ATE11401T1 (de) 1985-02-15
IE51219B1 (en) 1986-11-12
PT72801A (en) 1981-05-01
ES501243A0 (es) 1982-11-01
DK167481A (da) 1981-10-15
IE810818L (en) 1981-10-10
GR75192B (es) 1984-07-13
EP0038061B1 (en) 1985-01-23

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Legal Events

Date Code Title Description
MM4A Patent lapsed

Effective date: 19960506