ES538244A0 - Un procedimiento de preparar un derivado de trans-1,2-diaminociclohexil-amida. - Google Patents

Un procedimiento de preparar un derivado de trans-1,2-diaminociclohexil-amida.

Info

Publication number
ES538244A0
ES538244A0 ES538244A ES538244A ES538244A0 ES 538244 A0 ES538244 A0 ES 538244A0 ES 538244 A ES538244 A ES 538244A ES 538244 A ES538244 A ES 538244A ES 538244 A0 ES538244 A0 ES 538244A0
Authority
ES
Spain
Prior art keywords
diaminociclohexil
amida
trans
derivative
preparing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES538244A
Other languages
English (en)
Other versions
ES8607914A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Warner Lambert Co LLC
Original Assignee
Warner Lambert Co LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co LLC filed Critical Warner Lambert Co LLC
Publication of ES8607914A1 publication Critical patent/ES8607914A1/es
Publication of ES538244A0 publication Critical patent/ES538244A0/es
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ES538244A 1983-12-06 1984-12-04 Un procedimiento de preparar un derivado de trans-1,2-diaminociclohexil-amida. Granted ES538244A0 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US55873783A 1983-12-06 1983-12-06
US06/669,921 US4598087A (en) 1983-12-06 1984-11-13 Substituted trans-1,2-diaminocyclohexyl amide compounds

Publications (2)

Publication Number Publication Date
ES8607914A1 ES8607914A1 (es) 1986-01-01
ES538244A0 true ES538244A0 (es) 1986-01-01

Family

ID=27071831

Family Applications (1)

Application Number Title Priority Date Filing Date
ES538244A Granted ES538244A0 (es) 1983-12-06 1984-12-04 Un procedimiento de preparar un derivado de trans-1,2-diaminociclohexil-amida.

Country Status (17)

Country Link
US (1) US4598087A (es)
EP (1) EP0146297B1 (es)
AR (1) AR240798A1 (es)
AU (1) AU565237B2 (es)
CA (1) CA1235122A (es)
DE (1) DE3469168D1 (es)
DK (1) DK566784A (es)
ES (1) ES538244A0 (es)
FI (1) FI844752L (es)
GR (1) GR81172B (es)
HU (1) HU194547B (es)
IL (1) IL73660A (es)
NO (1) NO844854L (es)
NZ (1) NZ210441A (es)
OA (1) OA07884A (es)
PH (1) PH20657A (es)
PT (1) PT79628B (es)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4737493A (en) * 1985-07-01 1988-04-12 Warner-Lambert Company 7-((substituted)amino)-8-((substituted)carbonyl)-methylamino)-1-oxaspiro(4,5)decanes as analgesic agents
US4663343A (en) * 1985-07-19 1987-05-05 Warner-Lambert Company Substituted naphthalenyloxy-1,2-diaminocyclohexyl amide compounds
EP0232612B1 (en) * 1985-12-23 1990-04-04 Dr. Lo. Zambeletti S.p.A. Azacyclic compounds, processes for their preparation, and their use as pharmaceuticals
GB8608818D0 (en) * 1986-04-11 1986-05-14 Reckitt & Colmann Prod Ltd Pharmaceutical compositions
FR2617164B1 (fr) * 1987-06-25 1989-11-10 Roussel Uclaf Nouveaux derives de la decahydroquinoleine, leur procede de preparation, leur application comme medicaments et les compositions pharmaceutiques les renfermant
FR2617481B1 (fr) * 1987-07-03 1989-11-10 Roussel Uclaf Nouveaux derives de la tetrahydropyridine, leur procede de preparation et les intermediaires de preparation, leur application comme medicaments et les compositions pharmaceutiques les renfermant
US4855316A (en) * 1988-02-18 1989-08-08 Warner-Lambert Company 1,2-diamino-4,5-dimethoxycyclohexyl amide analgesic compounds
US5051428A (en) * 1988-12-06 1991-09-24 Warner-Lambert Company 2-amino-4 or 5-methoxycyclohexyl amides useful as analgesics
AU626949B2 (en) * 1988-12-06 1992-08-13 Warner-Lambert Company 2-amino-4 or 5-methoxycyclohexyl amides useful as analgesics
US5063242A (en) * 1989-04-21 1991-11-05 Warner-Lambert Company 7-((substituted)amino)-8-((substituted)carbonyl)-methylamino-1-oxaspiro[4,5]decanes as diuretics antiinflammatory, and cerebrovascular agents
US4965278A (en) 1989-04-21 1990-10-23 Warner-Lambert Company 7-(substituted)amino)-8-((substituted)carbonyl)-methylamino)-1-oxaspiro[4,5]decanes as diuretics antiiflammatory, and cerebrovascular agents
AU651641B2 (en) * 1991-12-27 1994-07-28 Warner-Lambert Company 2-amino-mono-methoxycyclohexyl amides useful as analgesics
EP0552386A1 (en) * 1992-01-13 1993-07-28 Warner-Lambert Company 2-Amino-3 or 6-methoxycyclohexyl amide derivatives
US5506257A (en) * 1992-03-26 1996-04-09 University Of British Columbia Aminocyclohexylamides for antiarrhythmic and anaesthetic uses
AU668932B2 (en) * 1992-03-26 1996-05-23 University Of British Columbia, The Method of blocking sodium channels or neuronal tissue
US5317028A (en) * 1992-09-08 1994-05-31 Warner-Lambert Co. 7-((substituted)amino)-8((substituted)carbonyl)-methylamino-1-oxaspiro(4,5)decanes useful in Parkinson's disease, dystonia, and other movement disorders
US5968968A (en) * 1996-07-24 1999-10-19 Warner-Lambert Company Diphenyl-cyclopropenes as selective K-agonists
KR100631299B1 (ko) * 1998-04-01 2006-10-09 카디오메 파마 코포레이션 아미노사이클로헥실 에테르 화합물 및 이를 포함하는 약제학적 조성물
WO2000051981A1 (en) * 1999-03-04 2000-09-08 Nortran Pharmaceuticals Inc. Aminocycloalkyl cinnamide compounds for arrhythmia and as analgesics and anesthetics
US7507545B2 (en) 1999-03-31 2009-03-24 Cardiome Pharma Corp. Ion channel modulating activity method
US7425537B2 (en) 2000-08-22 2008-09-16 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services SH2 domain binding inhibitors
US7524879B2 (en) * 2000-10-06 2009-04-28 Cardiome Pharma Corp. Ion channel modulating compounds and uses thereof
US7057053B2 (en) * 2000-10-06 2006-06-06 Cardiome Pharma Corp. Ion channel modulating compounds and uses thereof
US7345086B2 (en) * 2003-05-02 2008-03-18 Cardiome Pharma Corp. Uses of ion channel modulating compounds
JP4919661B2 (ja) * 2003-05-02 2012-04-18 カーディオム ファーマ コーポレイション アミノシクロヘキシルエーテル化合物およびそれらの用途
US20090041841A1 (en) * 2003-05-02 2009-02-12 Cardiome Pharma Corp. Controlled release tablet formulations for the prevention of arrhythmias
WO2005018635A2 (en) * 2003-08-07 2005-03-03 Cardiome Pharma Corp. Ion channel modulating activity i
US7345087B2 (en) * 2003-10-31 2008-03-18 Cardiome Pharma Corp. Aminocyclohexyl ether compounds and uses thereof
US7977373B2 (en) 2004-04-01 2011-07-12 Cardiome Pharma Corp. Prodrugs of ion channel modulating compounds and uses thereof
WO2005097087A2 (en) * 2004-04-01 2005-10-20 Cardiome Pharma Corp. Merged ion channel modulating compounds and uses thereof
EP1868598B1 (en) * 2004-11-08 2014-04-23 Cardiome Pharma Corp. A new dosing regimen for ion channel modulating compounds for treating acute atrial fibrillation in a human

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4145435A (en) * 1976-11-12 1979-03-20 The Upjohn Company 2-aminocycloaliphatic amide compounds
US4098904A (en) * 1976-11-12 1978-07-04 The Upjohn Company Analgesic n-(2-aminocycloaliphatic)benzamides
US4359476A (en) * 1981-04-09 1982-11-16 The Upjohn Company Adjacently substituted cycloalkane-amide analgesics
GB2096607B (en) * 1981-04-09 1985-02-27 Upjohn Co Aminocycloalkyl amides

Also Published As

Publication number Publication date
EP0146297A1 (en) 1985-06-26
EP0146297B1 (en) 1988-02-03
CA1235122A (en) 1988-04-12
US4598087A (en) 1986-07-01
AU565237B2 (en) 1987-09-10
DK566784A (da) 1985-06-07
GR81172B (en) 1985-04-04
PT79628A (en) 1985-01-01
ES8607914A1 (es) 1986-01-01
DK566784D0 (da) 1984-11-29
NO844854L (no) 1985-06-07
NZ210441A (en) 1989-01-27
AR240798A2 (es) 1991-02-28
OA07884A (en) 1986-11-20
HU194547B (en) 1988-02-29
DE3469168D1 (en) 1988-03-10
IL73660A (en) 1987-12-31
HUT36106A (en) 1985-08-28
FI844752A0 (fi) 1984-12-03
AR240798A1 (es) 1991-02-28
PT79628B (en) 1986-12-22
PH20657A (en) 1987-03-16
AU3630684A (en) 1985-06-13
FI844752L (fi) 1985-06-07

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