ES8207531A1 - Procedimiento para la preparacion de un nuevo derivado de lavincamina - Google Patents

Procedimiento para la preparacion de un nuevo derivado de lavincamina

Info

Publication number
ES8207531A1
ES8207531A1 ES506552A ES506552A ES8207531A1 ES 8207531 A1 ES8207531 A1 ES 8207531A1 ES 506552 A ES506552 A ES 506552A ES 506552 A ES506552 A ES 506552A ES 8207531 A1 ES8207531 A1 ES 8207531A1
Authority
ES
Spain
Prior art keywords
preparation
pharmaceutical compositions
compositions containing
new
vincamine derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES506552A
Other languages
English (en)
Other versions
ES506552A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medea Research SRL
Original Assignee
Medea Research SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medea Research SRL filed Critical Medea Research SRL
Publication of ES8207531A1 publication Critical patent/ES8207531A1/es
Publication of ES506552A0 publication Critical patent/ES506552A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D461/00—Heterocyclic compounds containing indolo [3,2,1-d,e] pyrido [3,2,1,j] [1,5]-naphthyridine ring systems, e.g. vincamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications

Abstract

PRODECIMIENTO PARA LA OBTENCION DEL 13A-ETIL-2,3,5,6,13A,13B-HEXAHIDRO-1H-INDOLO (3,2,1-DE)PIRIDO (3,2,1-IJ)-(1,5) NAFTIRIDINA-12-CARBOXILATO DE MATOXIMETILO,QUE TIENE APLICACIONES FARMACOLOGICAS POR SU ACTIVIDAD VASODILATADORA Y MICRORRELAJANTE. CONSISTE EN LA REACCION DE APOVINCAMINA EN FORMA DE SAL POTASICA CON BROMOMETILMETILETER. LA REACCION SE LLEVA A CABO EN CONDICIONES EQUIMOLECULARES, EN METILETILECETONA COMO DISOLVENTE, A UNA TEMPERATURA COMPRENDIDA ENTRE -5 Y 5C. CON AGUA, SE SECA, SE EVAPORA EL DISOLVENTE A PRESION REDUCIDA Y EL RESIDUO SE PURIFICA MEDIANTE CROMATOGRAFIA EN COLUMNA.
ES506552A 1980-11-14 1981-10-26 Procedimiento para la preparacion de un nuevo derivado de lavincamina Granted ES506552A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT25982/80A IT1148733B (it) 1980-11-14 1980-11-14 Derivati della vincamina,metodo per la sua preparazione e composizione farmaceutiche che lo contengono

Publications (2)

Publication Number Publication Date
ES8207531A1 true ES8207531A1 (es) 1982-10-01
ES506552A0 ES506552A0 (es) 1982-10-01

Family

ID=11218326

Family Applications (1)

Application Number Title Priority Date Filing Date
ES506552A Granted ES506552A0 (es) 1980-11-14 1981-10-26 Procedimiento para la preparacion de un nuevo derivado de lavincamina

Country Status (7)

Country Link
EP (1) EP0052238B1 (es)
JP (1) JPS605597B2 (es)
AR (1) AR229880A1 (es)
AT (1) ATE7392T1 (es)
DE (1) DE3163525D1 (es)
ES (1) ES506552A0 (es)
IT (1) IT1148733B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU187733B (en) * 1982-06-30 1986-02-28 Richter Gedeon Vegyeszeti Gyar Rt,Hu Process for preparing apovincaminic acid derivatives
JPH02167279A (ja) * 1988-09-30 1990-06-27 Taisho Pharmaceut Co Ltd アポビンカミン酸誘導体

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE790837A (fr) * 1971-11-03 1973-02-15 Richter Gedeon Vegeon Vegyesze Nouveaux esters alcaloides utiles comme vasodilatateurs cerebraux et leur procede de preparation
FR2259612B1 (es) * 1974-01-31 1977-09-09 Synthelabo
FR2275209A1 (fr) * 1974-06-21 1976-01-16 Synthelabo Nouveaux esters cetoniques, leurs sels, leur preparation et les medicaments qui les renferment

Also Published As

Publication number Publication date
JPS57112393A (en) 1982-07-13
JPS605597B2 (ja) 1985-02-12
ATE7392T1 (de) 1984-05-15
ES506552A0 (es) 1982-10-01
AR229880A1 (es) 1983-12-30
EP0052238B1 (en) 1984-05-09
DE3163525D1 (en) 1984-06-14
IT8025982A0 (it) 1980-11-14
EP0052238A1 (en) 1982-05-26
IT1148733B (it) 1986-12-03

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