ES8207166A1 - Un procedimiento para la preparacion de nuevos derivados de aminoalquilbenzofurano. - Google Patents

Un procedimiento para la preparacion de nuevos derivados de aminoalquilbenzofurano.

Info

Publication number
ES8207166A1
ES8207166A1 ES507269A ES507269A ES8207166A1 ES 8207166 A1 ES8207166 A1 ES 8207166A1 ES 507269 A ES507269 A ES 507269A ES 507269 A ES507269 A ES 507269A ES 8207166 A1 ES8207166 A1 ES 8207166A1
Authority
ES
Spain
Prior art keywords
aminoalkyl
production
compositions containing
benzofuran derivatives
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES507269A
Other languages
English (en)
Other versions
ES507269A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of ES507269A0 publication Critical patent/ES507269A0/es
Publication of ES8207166A1 publication Critical patent/ES8207166A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/81—Radicals substituted by nitrogen atoms not forming part of a nitro radical

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Furan Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

PROCEDIMIENTO DE BTENCION DE DERIVADOS DE AMINOALQUILBENZOFURANO. CONSISTE EN HACER REACCIONAR EL COMPUESTO (I) CON R2N=C=S PARA OBTENER EL COMPUESTO DE FORMULA GENERAL (II) EN QUE R1 Y R2 ON ALQUILO INFERIOR DE 1 A 3 ATOMOS DE CARBONO. X ES AZUFRE O UN GRUPO METILENO; N ES 2,3 O 4; R3 ES HIDROGENO, CICLOALQUILO INFERIOR, ALQUILO INFERIOR SUSTITUIDO CON CICLOALQUILO INFERIOR, ALQUILENO INFERIOR, ALQUINILO INFERIOR O FENILALQUILO INFERIOR, HIDROXIALQUILO INFERIOR (ALCOXI INFERIOR)-(ALQUILO INFERIOSTOS TIENEN APLICACIONES FARMACOLOGICAS POR SUS PROPIEDADR) Y DI(ALQUIL INFERIOR) AMINOALQUILO-INFERIOR.
ES507269A 1979-10-31 1981-11-18 Un procedimiento para la preparacion de nuevos derivados de aminoalquilbenzofurano. Expired ES8207166A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/089,808 US4238487A (en) 1979-10-31 1979-10-31 Aminoalkyl benzofuran derivatives

Publications (2)

Publication Number Publication Date
ES507269A0 ES507269A0 (es) 1982-09-01
ES8207166A1 true ES8207166A1 (es) 1982-09-01

Family

ID=22219673

Family Applications (2)

Application Number Title Priority Date Filing Date
ES496423A Expired ES8203360A1 (es) 1979-10-31 1980-10-30 Un procedimiento para la preparacion de nuevos derivados de aminoalquilbenzofurano.
ES507269A Expired ES8207166A1 (es) 1979-10-31 1981-11-18 Un procedimiento para la preparacion de nuevos derivados de aminoalquilbenzofurano.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES496423A Expired ES8203360A1 (es) 1979-10-31 1980-10-30 Un procedimiento para la preparacion de nuevos derivados de aminoalquilbenzofurano.

Country Status (9)

Country Link
US (1) US4238487A (es)
EP (1) EP0029311B1 (es)
JP (1) JPS5675484A (es)
AT (1) ATE11413T1 (es)
DE (1) DE3070032D1 (es)
DK (1) DK460380A (es)
ES (2) ES8203360A1 (es)
GR (1) GR70726B (es)
PT (1) PT71965B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4404207A (en) * 1981-11-06 1983-09-13 Riker Laboratories, Inc. Antimicrobial 8-substituted benzo [IJ]quinolizines
US4612309A (en) * 1984-10-23 1986-09-16 William H. Rorer, Inc. Antisecretory bicyclic benzo-oxy heterocyclic ethers and thioethers
JPS63139180A (ja) * 1986-12-02 1988-06-10 Tanabe Seiyaku Co Ltd カルボン酸誘導体

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE663926A (es) * 1964-05-20
GB1338169A (en) * 1971-03-09 1973-11-21 Smith Kline French Lab Ureas thioureas and guanidines
GB1472959A (en) * 1974-09-26 1977-05-11 Roche Products Ltd Benzofuran derivatives and a process for the manufacture thereof
GB1565966A (en) * 1976-08-04 1980-04-23 Allen & Hanburys Ltd Aminoalkyl furan derivatives
IE46886B1 (en) * 1977-05-17 1983-10-19 Allen & Hanburys Ltd Aminoalkyl-benzene derivatives
DE2835695A1 (de) 1977-08-29 1979-03-15 Yamanouchi Pharma Co Ltd Neue heterocyclische verbindungen, verfahren zu ihrer herstellung und arzneimittel, die diese enthalten
EP0001699B1 (en) * 1977-10-11 1982-02-24 Glaxo Group Limited Derivatives of furyl compounds, their preparation and pharmaceutical compositions containing them
US4233302A (en) * 1977-12-23 1980-11-11 Glaxo Group Limited Amine derivatives and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
US4238487A (en) 1980-12-09
ES507269A0 (es) 1982-09-01
ES496423A0 (es) 1982-04-01
ATE11413T1 (de) 1985-02-15
PT71965B (en) 1982-03-31
EP0029311B1 (en) 1985-01-23
DE3070032D1 (en) 1985-03-07
JPS5675484A (en) 1981-06-22
DK460380A (da) 1981-05-01
GR70726B (es) 1983-01-24
EP0029311A1 (en) 1981-05-27
ES8203360A1 (es) 1982-04-01
PT71965A (en) 1980-11-01

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20000403