ES8205859A2 - Procedimiento para la obtencion de compuestos de acido 17-c-esteroide- -propionico - Google Patents
Procedimiento para la obtencion de compuestos de acido 17-c-esteroide- -propionicoInfo
- Publication number
- ES8205859A2 ES8205859A2 ES489318A ES48931880A ES8205859A2 ES 8205859 A2 ES8205859 A2 ES 8205859A2 ES 489318 A ES489318 A ES 489318A ES 48931880 A ES48931880 A ES 48931880A ES 8205859 A2 ES8205859 A2 ES 8205859A2
- Authority
- ES
- Spain
- Prior art keywords
- microorganism
- preparation
- mutants
- steroid
- side chains
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/01—Preparation of mutants without inserting foreign genetic material therein; Screening processes therefor
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
- C07J9/005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane containing a carboxylic function directly attached or attached by a chain containing only carbon atoms to the cyclopenta[a]hydrophenanthrene skeleton
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P33/00—Preparation of steroids
- C12P33/005—Degradation of the lateral chains at position 17
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Plant Pathology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Steroid Compounds (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DE ACIDO 17-C-ESTEROTIDE-PROPIONICO, DE SUSTRATOS DE ESTEROIDES DE CADENAS LATERALES 17-C,MEDIANTE DEGRADACION SELECTIVA DE CADENAS LATERALES, EN CONDICIONES AEROBIAS Y DE INHIBIDORES DE LA DEGRADACION Y O DEL CRECIMIENTO DEL ANILLO. CONSISTE EN AISLAR Y CULTIVAR AEROBICAMENTE UNA CEPA SALVAJE DE MICROORGANISMOS CAPACITADA PARA EL CRECIMIENTO SOBRE COMPUESTOS DE ETERINA COMO UNICA FUENTE DE CARBONO; SOMETERLA A UN TRATAMIENTO SOBRE COMPUESTOS DE ESTERINA COMO UNICA FUENTES DE CARBONO; SOMETERLA A UNA TRATAMIENTO DE MUTACION POR METODOS CONVENCIONALES, CULTIVAR LA POPULACION DE MUTANTES QUE PROPORCIONAN LAS COMPUESTOS DE ACIDO 17-C Y AISLAR LAS CEPAS DE MUTANTES CON PRODUCCION OPTIMA DE DICHOS COMPUESTOS. ESTOS COMPUESTOS TIENE APLICACIONES PARA LA OBTENCION DE ESTEROIDES DE LA SERIE PROGESTERONA.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AT0170979A AT386225B (de) | 1979-03-07 | 1979-03-07 | Verfahren zur hestellung von 17-c-steroid-alpha- propionsaeureverbindungen, insbesondere von 3-oxopregna-4-en-20-carbons|ure und/oder 3-oxo-pregna-1,4-dien-20-carbonsaeure |
Publications (2)
Publication Number | Publication Date |
---|---|
ES489318A0 ES489318A0 (es) | 1982-07-01 |
ES8205859A2 true ES8205859A2 (es) | 1982-07-01 |
Family
ID=3519283
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES489318A Expired ES8205859A2 (es) | 1979-03-07 | 1980-03-07 | Procedimiento para la obtencion de compuestos de acido 17-c-esteroide- -propionico |
Country Status (11)
Country | Link |
---|---|
US (1) | US4362815A (es) |
EP (1) | EP0015308B1 (es) |
JP (2) | JPS55127991A (es) |
AT (1) | AT386225B (es) |
AU (1) | AU538431B2 (es) |
BR (1) | BR8001330A (es) |
CA (1) | CA1141313A (es) |
DE (1) | DE2967658D1 (es) |
DK (1) | DK91680A (es) |
ES (1) | ES8205859A2 (es) |
NO (1) | NO800647L (es) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3112981A1 (de) * | 1981-04-01 | 1982-10-21 | Henkel KGaA, 4000 Düsseldorf | Verfahren zum gezielten mikrobiologischen abbau von gallensaeuren |
AU581183B2 (en) * | 1983-08-12 | 1989-02-16 | Commonwealth Scientific And Industrial Research Organisation | Process for the microbial preparation of steroid drug intermediates |
NL8803141A (nl) * | 1988-12-22 | 1990-07-16 | Tno | Werkwijze voor de microbiologische bereiding van steroiden; daarvoor bruikbare genetisch gemodificeerde micro-organismen. |
CA2099526C (fr) * | 1993-07-02 | 2005-06-21 | Hydro-Quebec | Additifs pour lubrifiants utilises dans le laminage de feuillards de lithium en films minces |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3759791A (en) * | 1970-12-10 | 1973-09-18 | Searle & Co | Selective microbiological preparation of androst-4-ene-3,17-dione |
US4032408A (en) * | 1975-04-30 | 1977-06-28 | G. D. Searle & Co. | Process of preparing 3-oxo-pregna-4,17(20)-dien-21-carboxylic acid and esters with mycobacterium |
US4029549A (en) * | 1976-03-26 | 1977-06-14 | The Upjohn Company | Process of producing 9α-hydroxy-3-ketobisnorchol-4-en-22-oic with mycobacterium fortuitum |
US4062729A (en) * | 1976-11-26 | 1977-12-13 | The Upjohn Company | Microbial transformation of steroids |
AT362086B (de) * | 1978-04-17 | 1981-04-27 | Henkel Kgaa | Verfahren zur herstellung von 17-c-steroid- -alpha-propionsaeureverbindungen durch mikro- biellen seitenkettenabbau an 17-c-seitenketten- -steroidsubstraten |
-
1979
- 1979-03-07 AT AT0170979A patent/AT386225B/de not_active IP Right Cessation
- 1979-10-29 EP EP79104165A patent/EP0015308B1/de not_active Expired
- 1979-10-29 DE DE7979104165T patent/DE2967658D1/de not_active Expired
-
1980
- 1980-03-04 DK DK91680A patent/DK91680A/da not_active Application Discontinuation
- 1980-03-04 AU AU56133/80A patent/AU538431B2/en not_active Ceased
- 1980-03-06 NO NO800647A patent/NO800647L/no unknown
- 1980-03-06 BR BR8001330A patent/BR8001330A/pt unknown
- 1980-03-07 ES ES489318A patent/ES8205859A2/es not_active Expired
- 1980-03-07 JP JP2972780A patent/JPS55127991A/ja active Pending
- 1980-03-07 US US06/128,223 patent/US4362815A/en not_active Expired - Lifetime
- 1980-03-07 CA CA000347206A patent/CA1141313A/en not_active Expired
-
1989
- 1989-08-07 JP JP1205546A patent/JPH02119795A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
AT386225B (de) | 1988-07-25 |
AU538431B2 (en) | 1984-08-16 |
EP0015308A1 (de) | 1980-09-17 |
EP0015308B1 (de) | 1987-04-29 |
ES489318A0 (es) | 1982-07-01 |
JPS55127991A (en) | 1980-10-03 |
BR8001330A (pt) | 1980-11-04 |
ATA170979A (de) | 1987-12-15 |
CA1141313A (en) | 1983-02-15 |
NO800647L (no) | 1980-09-08 |
DK91680A (da) | 1980-09-08 |
JPH02119795A (ja) | 1990-05-07 |
US4362815A (en) | 1982-12-07 |
DE2967658D1 (en) | 1987-06-04 |
AU5613380A (en) | 1980-09-11 |
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