ES8204414A1 - Procedimiento para preparar derivados amidicos de acido p- isobutil-fenil-propionico - Google Patents
Procedimiento para preparar derivados amidicos de acido p- isobutil-fenil-propionicoInfo
- Publication number
- ES8204414A1 ES8204414A1 ES504156A ES504156A ES8204414A1 ES 8204414 A1 ES8204414 A1 ES 8204414A1 ES 504156 A ES504156 A ES 504156A ES 504156 A ES504156 A ES 504156A ES 8204414 A1 ES8204414 A1 ES 8204414A1
- Authority
- ES
- Spain
- Prior art keywords
- isobutyl
- phenyl
- propionic acid
- amides
- substituted amine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- HEFNNWSXXWATRW-UHFFFAOYSA-N Ibuprofen Chemical compound CC(C)CC1=CC=C(C(C)C(O)=O)C=C1 HEFNNWSXXWATRW-UHFFFAOYSA-N 0.000 title abstract 2
- 150000001408 amides Chemical class 0.000 title 1
- 150000001412 amines Chemical class 0.000 abstract 2
- WHUUTDBJXJRKMK-UHFFFAOYSA-N Glutamic acid Natural products OC(=O)C(N)CCC(O)=O WHUUTDBJXJRKMK-UHFFFAOYSA-N 0.000 abstract 1
- CKLJMWTZIZZHCS-REOHCLBHSA-N L-aspartic acid Chemical compound OC(=O)[C@@H](N)CC(O)=O CKLJMWTZIZZHCS-REOHCLBHSA-N 0.000 abstract 1
- WHUUTDBJXJRKMK-VKHMYHEASA-N L-glutamic acid Chemical compound OC(=O)[C@@H](N)CCC(O)=O WHUUTDBJXJRKMK-VKHMYHEASA-N 0.000 abstract 1
- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 abstract 1
- 239000004472 Lysine Substances 0.000 abstract 1
- -1 amide derivatives of p-isobutyl-phenyl-propionic acid Chemical class 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 235000003704 aspartic acid Nutrition 0.000 abstract 1
- OQFSQFPPLPISGP-UHFFFAOYSA-N beta-carboxyaspartic acid Natural products OC(=O)C(N)C(C(O)=O)C(O)=O OQFSQFPPLPISGP-UHFFFAOYSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000002349 favourable effect Effects 0.000 abstract 1
- 235000013922 glutamic acid Nutrition 0.000 abstract 1
- 239000004220 glutamic acid Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/02—Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/12—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pain & Pain Management (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Rheumatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT23601/80A IT1193955B (it) | 1980-07-22 | 1980-07-22 | Derivati ammidici dell'acido p-isobutilfenilpropionico, procedimento per la loro preparazione e relative composizioni farmaceutici |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES504156A0 ES504156A0 (es) | 1982-05-16 |
| ES8204414A1 true ES8204414A1 (es) | 1982-05-16 |
Family
ID=11208465
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES504156A Expired ES8204414A1 (es) | 1980-07-22 | 1981-07-21 | Procedimiento para preparar derivados amidicos de acido p- isobutil-fenil-propionico |
Country Status (16)
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4536346A (en) * | 1983-05-06 | 1985-08-20 | American Cyanamid Company | Aralkanamidophenyl compounds |
| HU198446B (en) * | 1987-09-25 | 1989-10-30 | Richter Gedeon Vegyeszet | Process for production of new amids of buten acid and medical compositions containing such active substances |
| IT1317826B1 (it) * | 2000-02-11 | 2003-07-15 | Dompe Spa | Ammidi, utili nell'inibizione della chemiotassi dei neutrofiliindotta da il-8. |
| IT1318466B1 (it) * | 2000-04-14 | 2003-08-25 | Dompe Spa | Ammidi di acidi r-2-(amminoaril)-propionici, utili nella prevenzionedell'attivazione leucocitaria. |
| ITMI20010395A1 (it) * | 2001-02-27 | 2002-08-27 | Dompe Spa | Omega-amminoalchilammidi di acidi r-2-aril-propionici come inibitori della chemiotassi di cellule polimorfonucleate e mononucleate |
| EP1457485A1 (en) | 2003-03-14 | 2004-09-15 | Dompé S.P.A. | Sulfonic acids, their derivatives and pharmaceutical compositions containing them |
-
1980
- 1980-07-22 IT IT23601/80A patent/IT1193955B/it active
-
1981
- 1981-07-14 GB GB8121623A patent/GB2080797B/en not_active Expired
- 1981-07-17 CA CA000381957A patent/CA1181419A/en not_active Expired
- 1981-07-20 IN IN809/CAL/81A patent/IN153746B/en unknown
- 1981-07-20 DE DE3128676A patent/DE3128676C2/de not_active Expired
- 1981-07-20 PT PT73400A patent/PT73400B/pt unknown
- 1981-07-20 LU LU83497A patent/LU83497A1/de unknown
- 1981-07-21 KR KR1019810002639A patent/KR840001072B1/ko not_active Expired
- 1981-07-21 MX MX819564U patent/MX7038E/es unknown
- 1981-07-21 AR AR286159A patent/AR226734A1/es active
- 1981-07-21 CH CH4755/81A patent/CH648292A5/it not_active IP Right Cessation
- 1981-07-21 JP JP56113098A patent/JPS5742663A/ja active Pending
- 1981-07-21 ES ES504156A patent/ES8204414A1/es not_active Expired
- 1981-07-22 FR FR8114252A patent/FR2491456B1/fr not_active Expired
- 1981-07-22 BE BE0/205465A patent/BE889699A/fr not_active IP Right Cessation
- 1981-07-22 BR BR8104728A patent/BR8104728A/pt unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BE889699A (fr) | 1981-11-16 |
| PT73400B (en) | 1982-10-01 |
| DE3128676A1 (de) | 1982-04-22 |
| CA1181419A (en) | 1985-01-22 |
| DE3128676C2 (de) | 1983-12-01 |
| KR830006185A (ko) | 1983-09-20 |
| AR226734A1 (es) | 1982-08-13 |
| IT1193955B (it) | 1988-08-31 |
| GB2080797B (en) | 1984-01-18 |
| BR8104728A (pt) | 1982-04-13 |
| PT73400A (en) | 1981-08-01 |
| KR840001072B1 (ko) | 1984-07-31 |
| MX7038E (es) | 1987-03-18 |
| ES504156A0 (es) | 1982-05-16 |
| CH648292A5 (it) | 1985-03-15 |
| FR2491456B1 (enrdf_load_stackoverflow) | 1985-11-15 |
| IT8023601A0 (it) | 1980-07-22 |
| JPS5742663A (en) | 1982-03-10 |
| GB2080797A (en) | 1982-02-10 |
| LU83497A1 (de) | 1981-10-29 |
| FR2491456A1 (enrdf_load_stackoverflow) | 1982-04-09 |
| IN153746B (enrdf_load_stackoverflow) | 1984-08-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19991007 |