ES8203609A1 - Procedimiento de obtencion de preparados promotores de la coagulacion sanguinea - Google Patents
Procedimiento de obtencion de preparados promotores de la coagulacion sanguineaInfo
- Publication number
- ES8203609A1 ES8203609A1 ES502497A ES502497A ES8203609A1 ES 8203609 A1 ES8203609 A1 ES 8203609A1 ES 502497 A ES502497 A ES 502497A ES 502497 A ES502497 A ES 502497A ES 8203609 A1 ES8203609 A1 ES 8203609A1
- Authority
- ES
- Spain
- Prior art keywords
- coagulation
- blood
- preparing
- methods
- promoting products
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
- C12N9/647—Blood coagulation factors not provided for in a preceding group or according to more than one of the proceeding groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/827—Proteins from mammals or birds
- Y10S530/829—Blood
- Y10S530/83—Plasma; serum
- Y10S530/831—Cohn fractions
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Hematology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE PREPARADOS PROMOTORES DE LA COAGULACION SANGUINEA, LIBRES DE TROMBINA DE PLASMA SANGUINEO HUMANO. CONSISTE EN PASAR, A TRAVES DE UN INTERCAMBIADOR DE ANIONES, UNA FRACCION DE PLASMA SANGUINEO HUMANO QUE CONTIENE FACTORES DE COAGULACION II, VII, IX Y X; ELUDIR LOS FACTORES DE COAGULACION ABSORBIDOS CON UNA DISOLUCION ACUOSA DE BICARBONATO AMONICO DE PH 7-9; TRATAR EL ELUATO CON IONES CALCIO EN UNA CONCENTRACION DE 0,0005 A 0,000, MOLAR PARA GENERAR UNA SUSTANCIA DE ACTIVIDAD DESVIANTE DEL FACTOR VIII.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/153,341 US4364861A (en) | 1980-05-27 | 1980-05-27 | Blood-coagulation-promoting products and methods of preparing them |
Publications (2)
Publication Number | Publication Date |
---|---|
ES502497A0 ES502497A0 (es) | 1982-04-01 |
ES8203609A1 true ES8203609A1 (es) | 1982-04-01 |
Family
ID=22546793
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES502497A Expired ES8203609A1 (es) | 1980-05-27 | 1981-05-26 | Procedimiento de obtencion de preparados promotores de la coagulacion sanguinea |
Country Status (6)
Country | Link |
---|---|
US (1) | US4364861A (es) |
EP (1) | EP0041173B2 (es) |
AT (1) | ATE9354T1 (es) |
CA (1) | CA1170182A (es) |
DE (1) | DE3165965D1 (es) |
ES (1) | ES8203609A1 (es) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4404132A (en) * | 1980-05-27 | 1983-09-13 | Cutter Laboratories, Inc. | Blood coagulation promoting product |
AT368883B (de) * | 1980-07-22 | 1982-11-25 | Immuno Ag | Verfahren zur herstellung einer neuen blutgerinnungsfoerdernden praeparation auf basis von humanproteinen |
USRE32011E (en) * | 1981-12-14 | 1985-10-22 | Scripps Clinic And Research Foundation | Ultrapurification of factor VIII using monoclonal antibodies |
US4495175A (en) * | 1982-08-05 | 1985-01-22 | University Of Rochester | Preparation of highly purified human antihemophilic factor |
DE3336631A1 (de) * | 1983-10-08 | 1985-04-18 | Behringwerke Ag, 3550 Marburg | Verfahren zur pasteurisierung von plasma oder von konzentraten der blutgerinnungsfaktoren ii, vii, ix und x |
US5149787A (en) * | 1984-05-22 | 1992-09-22 | The Blood Center Research Foundation | Method for maintaining intact, non-degraded factor VIII/von-Willebrand factor during blood processing |
US4710381A (en) * | 1984-05-22 | 1987-12-01 | The Blood Center Of Southeastern Wisconsin | Method for maintaining intact, non-degraded factor VIII/von-Willebrand factor during blood processing |
GB2178533B (en) * | 1985-07-22 | 1989-07-19 | Asahi Chemical Ind | Analytical method of enzyme precursors and device therefor |
DE3625090A1 (de) * | 1986-07-24 | 1988-01-28 | Behringwerke Ag | Mittel zur therapie faktor viii-resistenter haemophilie a und verfahren zu seiner herstellung |
US4725673A (en) * | 1986-08-29 | 1988-02-16 | Alpha Therapeutic Corporation | Plasma fraction purification using silica resin bound to a ligand |
DE3843126C3 (de) * | 1988-12-22 | 1994-10-06 | Octapharma Ag | Verfahren zur Herstellung eines hochreinen Thrombinkonzentrates |
AT398079B (de) * | 1991-11-04 | 1994-09-26 | Immuno Ag | Präparation mit thrombinaktivität sowie verfahren zu ihrer herstellung |
DE19531637A1 (de) * | 1995-08-28 | 1997-03-06 | Immuno Ag | Pharmazeutische Zusammensetzung zur Behandlung von Blutgerinnungsstörugnen, Verfahren zur Herstellung derselben und deren Verwendung |
PT3225233T (pt) | 2005-11-01 | 2019-10-24 | Wyeth Llc | Solução de cloreto de sódio para reconstituição de fármacos. |
RU2559576C1 (ru) * | 2014-06-09 | 2015-08-10 | Федеральное государственное бюджетное учреждение Гематологический научный центр Министерства здравоохранения РФ | Способ получения вирусбезопасного полного протромбинового комплекса |
FR3026644B1 (fr) * | 2014-10-07 | 2018-01-05 | Laboratoire Francais Du Fractionnement Et Des Biotechnologies | Colle biologique et son utilisation comme medicament |
CN105440127B (zh) * | 2015-12-30 | 2018-10-16 | 上海莱士血液制品股份有限公司 | 一种以人血浆Cohn组分III为原料的FEIBA的制备方法 |
RU2648517C1 (ru) * | 2017-06-23 | 2018-03-26 | Федеральное государственное бюджетное учреждение Гематологический научный центр Министерства здравоохранения Российской Федерации (ФГБУ ГНЦ Минздрава России) | Способ получения лиофилизированного препарата активированного протромбинового комплекса, обладающего фактор viii-шунтирующей активностью |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3717708A (en) * | 1968-10-24 | 1973-02-20 | Cutter Lab | Blood coagulation complex |
US3560475A (en) * | 1969-06-19 | 1971-02-02 | Baxter Laboratories Inc | Prothrombin complex prepared by precipitation with polyethylene glycol |
US3682881A (en) * | 1970-10-02 | 1972-08-08 | Baxter Laboratories Inc | Fractionation of plasma using glycine and polyethylene glycol |
DE2459291C3 (de) * | 1974-12-14 | 1981-06-04 | Biotest-Serum-Institut Gmbh, 6000 Frankfurt | Verfahren zur Herstellung eines antihämophiles Globulin A enthaltenden Konzentrats neben einem Prothrombin- Komplex und einer Lösung von lagerstabilen Serumproteinen |
US4170590A (en) * | 1974-12-14 | 1979-10-09 | Biotest-Serum-Institut Gmbh | Ion exchanger treatment of citrate-stabilized plasma |
US4056222A (en) * | 1975-08-25 | 1977-11-01 | Focke & Pfuhl | Compartmentalized structure with pivotable separating webs |
SE405549B (sv) * | 1975-10-09 | 1978-12-18 | Pharmacia Fine Chemicals Ab | Forfarande for isolering av albumin ur plasmaprodukter genom kromatografisk fraktionering |
AT350726B (de) * | 1976-08-30 | 1979-06-11 | Immuno Ag | Verfahren zur herstellung einer blut- gerinnungsfoerdernden praeperation aus menschlichem blutplasma |
DE2902158A1 (de) * | 1979-01-20 | 1980-07-31 | Biotest Serum Institut Gmbh | Verfahren zur herstellung von fibrinogen, einem die gerinnungsfaktoren ii, vii, ix und x enthaltenden prothrombinkomplex, antithrombin iii und einer loesung von lagerstabilen serumproteinen |
-
1980
- 1980-05-27 US US06/153,341 patent/US4364861A/en not_active Expired - Lifetime
-
1981
- 1981-05-18 EP EP81103791A patent/EP0041173B2/en not_active Expired - Lifetime
- 1981-05-18 DE DE8181103791T patent/DE3165965D1/de not_active Expired
- 1981-05-18 AT AT81103791T patent/ATE9354T1/de not_active IP Right Cessation
- 1981-05-26 CA CA000378329A patent/CA1170182A/en not_active Expired
- 1981-05-26 ES ES502497A patent/ES8203609A1/es not_active Expired
Also Published As
Publication number | Publication date |
---|---|
EP0041173B1 (en) | 1984-09-12 |
EP0041173A1 (en) | 1981-12-09 |
US4364861A (en) | 1982-12-21 |
DE3165965D1 (en) | 1984-10-18 |
ES502497A0 (es) | 1982-04-01 |
EP0041173B2 (en) | 1992-11-11 |
ATE9354T1 (de) | 1984-09-15 |
CA1170182A (en) | 1984-07-03 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 20020206 |