FR2210396A1 - Blood coagulation complex - by extraction of plasma with sephadex - Google Patents
Blood coagulation complex - by extraction of plasma with sephadexInfo
- Publication number
- FR2210396A1 FR2210396A1 FR7245324A FR7245324A FR2210396A1 FR 2210396 A1 FR2210396 A1 FR 2210396A1 FR 7245324 A FR7245324 A FR 7245324A FR 7245324 A FR7245324 A FR 7245324A FR 2210396 A1 FR2210396 A1 FR 2210396A1
- Authority
- FR
- France
- Prior art keywords
- plasma
- sephadex
- extraction
- mixt
- blood coagulation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
- C12N9/647—Blood coagulation factors not provided for in a preceding group or according to more than one of the proceeding groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Abstract
A storage stable mixt. of coagulation Factors II, VII, IX and X in non-activated form, in the same proportions as in natural human plasma and free of thrombin activated Factor X, depressor activity and anti-complement activity, is prepared by selective absorption from Effluent I, prepared by Cohn method 6 from natural human plasma, onto an ion exchanger. This ion exchanger consists of cross-linked dextran substituted by diethylaminoethyl gps. The mixt of factors is then eluted with a soln of a volatile salt. The product is used for treating coagulation disorders, e.g. for haemophilia.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7245324A FR2210396A1 (en) | 1972-12-19 | 1972-12-19 | Blood coagulation complex - by extraction of plasma with sephadex |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7245324A FR2210396A1 (en) | 1972-12-19 | 1972-12-19 | Blood coagulation complex - by extraction of plasma with sephadex |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2210396A1 true FR2210396A1 (en) | 1974-07-12 |
FR2210396B1 FR2210396B1 (en) | 1978-03-24 |
Family
ID=9108977
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7245324A Granted FR2210396A1 (en) | 1972-12-19 | 1972-12-19 | Blood coagulation complex - by extraction of plasma with sephadex |
Country Status (1)
Country | Link |
---|---|
FR (1) | FR2210396A1 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0239565A2 (en) * | 1986-03-27 | 1987-09-30 | Thomas Prof. Dr. Vukovich | Method of separating proteins |
-
1972
- 1972-12-19 FR FR7245324A patent/FR2210396A1/en active Granted
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0239565A2 (en) * | 1986-03-27 | 1987-09-30 | Thomas Prof. Dr. Vukovich | Method of separating proteins |
EP0239565A3 (en) * | 1986-03-27 | 1989-07-26 | Thomas Prof. Dr. Vukovich | Method of and apparatus for separating proteins |
Also Published As
Publication number | Publication date |
---|---|
FR2210396B1 (en) | 1978-03-24 |
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