ES8106002A1 - Procedimiento para preparar un nuevo derivado de tiazol (3,2-c)benzoxazina-1,3 - Google Patents
Procedimiento para preparar un nuevo derivado de tiazol (3,2-c)benzoxazina-1,3Info
- Publication number
- ES8106002A1 ES8106002A1 ES495621A ES495621A ES8106002A1 ES 8106002 A1 ES8106002 A1 ES 8106002A1 ES 495621 A ES495621 A ES 495621A ES 495621 A ES495621 A ES 495621A ES 8106002 A1 ES8106002 A1 ES 8106002A1
- Authority
- ES
- Spain
- Prior art keywords
- preparation
- thiazolo
- pharmaceutical compositions
- compositions containing
- benzoxazine derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Pain & Pain Management (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Rheumatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DE TIAZOL-[3,2-C]-BENZOXACINA-1,3 DE FORMULA (I), Y EVENTUALMENTE DE SUS SALES METALICAS Y DE ADICION CON BASES ORGANICAS NITROGENADAS, EN LA QUE X ES UN ATOMO DE OXIGENO O DE AZUFRE, R3 ES UN HIDROGENO O UN RADICAL CARBOXI Y R1 Y R2 PUEDEN SER VARIOS TIPOS DE RADICALES. CONSISTE EN LA REACCION DE CONDENSACION CON CIERRE DE ANILLO ENTRE UN COMPUESTO DE FORMULA Y2C=X, EN LA QUE X TIENE EL MISMO SIGNIFICADO QUE EN LA FORMULA (I) E Y ES CLORO O DIVERSOS TIPOS DE RADICALES AZOLILO, Y UN COMPUESTO DE FORMULA (II), EN LA QUE R1, R2 Y R3 SON LOS MISMOS QUE EN LA FORMULA (I). LA REACCION SE LLEVA A CABO EN UN DISOLVENTE ORGANCIO AROMATICO A UNA TEMPERATURA ENTRE -20 GC Y LA DE REFLUJO DE LA MEZCLA. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS POR SU ACTIVIDAD ANALGESICA, ANTINFLAMATORIA Y ANTITERMICA. *FORMULA*
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7924833A FR2466470A1 (fr) | 1979-10-05 | 1979-10-05 | Nouveaux derives de la thiazolo(3,2-c) benzoxazine-1,3, leur preparation et les medicaments qui les contiennent |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8106002A1 true ES8106002A1 (es) | 1981-07-01 |
ES495621A0 ES495621A0 (es) | 1981-07-01 |
Family
ID=9230361
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES495621A Granted ES495621A0 (es) | 1979-10-05 | 1980-10-03 | Procedimiento para preparar un nuevo derivado de tiazol (3,2-c)benzoxazina-1,3 |
Country Status (23)
Country | Link |
---|---|
US (1) | US4291032A (es) |
EP (1) | EP0027085B1 (es) |
JP (1) | JPS5661389A (es) |
AR (1) | AR226075A1 (es) |
AT (1) | ATE5590T1 (es) |
AU (1) | AU6292880A (es) |
CA (1) | CA1140548A (es) |
CS (1) | CS219290B2 (es) |
DE (1) | DE3065904D1 (es) |
DK (1) | DK418080A (es) |
ES (1) | ES495621A0 (es) |
FI (1) | FI803142L (es) |
FR (1) | FR2466470A1 (es) |
GR (1) | GR69361B (es) |
HU (1) | HU178159B (es) |
IL (1) | IL61200A0 (es) |
NO (1) | NO802920L (es) |
NZ (1) | NZ195160A (es) |
OA (1) | OA06641A (es) |
PT (1) | PT71871B (es) |
SU (1) | SU1072810A3 (es) |
YU (1) | YU253280A (es) |
ZA (1) | ZA806144B (es) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN112159363B (zh) * | 2020-10-28 | 2023-05-02 | 兰州大学 | 一种制备1,3-苯并噁嗪三氟甲基化官能化衍生物的方法 |
-
1979
- 1979-10-05 FR FR7924833A patent/FR2466470A1/fr active Granted
-
1980
- 1980-10-02 US US06/192,988 patent/US4291032A/en not_active Expired - Lifetime
- 1980-10-02 NO NO802920A patent/NO802920L/no unknown
- 1980-10-03 FI FI803142A patent/FI803142L/fi not_active Application Discontinuation
- 1980-10-03 SU SU802993203A patent/SU1072810A3/ru active
- 1980-10-03 CA CA000361540A patent/CA1140548A/fr not_active Expired
- 1980-10-03 DE DE8080401411T patent/DE3065904D1/de not_active Expired
- 1980-10-03 YU YU02532/80A patent/YU253280A/xx unknown
- 1980-10-03 GR GR63043A patent/GR69361B/el unknown
- 1980-10-03 DK DK418080A patent/DK418080A/da unknown
- 1980-10-03 ES ES495621A patent/ES495621A0/es active Granted
- 1980-10-03 EP EP80401411A patent/EP0027085B1/fr not_active Expired
- 1980-10-03 ZA ZA00806144A patent/ZA806144B/xx unknown
- 1980-10-03 PT PT71871A patent/PT71871B/pt unknown
- 1980-10-03 AT AT80401411T patent/ATE5590T1/de active
- 1980-10-03 HU HU80802424A patent/HU178159B/hu unknown
- 1980-10-03 AU AU62928/80A patent/AU6292880A/en not_active Abandoned
- 1980-10-05 IL IL61200A patent/IL61200A0/xx unknown
- 1980-10-06 AR AR282790A patent/AR226075A1/es active
- 1980-10-06 NZ NZ195160A patent/NZ195160A/xx unknown
- 1980-10-06 CS CS806738A patent/CS219290B2/cs unknown
- 1980-10-06 JP JP13971580A patent/JPS5661389A/ja active Pending
- 1980-10-16 OA OA57238A patent/OA06641A/xx unknown
Also Published As
Publication number | Publication date |
---|---|
GR69361B (es) | 1982-05-20 |
PT71871B (fr) | 1981-09-03 |
EP0027085B1 (fr) | 1983-12-14 |
ZA806144B (en) | 1981-09-30 |
HU178159B (en) | 1982-03-28 |
ATE5590T1 (de) | 1983-12-15 |
FI803142L (fi) | 1981-04-06 |
NO802920L (no) | 1981-04-06 |
DK418080A (da) | 1981-04-06 |
CA1140548A (fr) | 1983-02-01 |
CS219290B2 (en) | 1983-03-25 |
FR2466470A1 (fr) | 1981-04-10 |
JPS5661389A (en) | 1981-05-26 |
FR2466470B1 (es) | 1982-10-01 |
AR226075A1 (es) | 1982-05-31 |
IL61200A0 (en) | 1980-12-31 |
NZ195160A (en) | 1982-03-30 |
OA06641A (fr) | 1981-08-31 |
AU6292880A (en) | 1981-04-16 |
DE3065904D1 (en) | 1984-01-19 |
EP0027085A1 (fr) | 1981-04-15 |
SU1072810A3 (ru) | 1984-02-07 |
YU253280A (en) | 1983-01-21 |
ES495621A0 (es) | 1981-07-01 |
PT71871A (fr) | 1980-11-01 |
US4291032A (en) | 1981-09-22 |
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