ES8105699A1 - Un metodo para aislar un polipeptido espasmolitico pancreatico purificado. - Google Patents
Un metodo para aislar un polipeptido espasmolitico pancreatico purificado.Info
- Publication number
- ES8105699A1 ES8105699A1 ES494917A ES494917A ES8105699A1 ES 8105699 A1 ES8105699 A1 ES 8105699A1 ES 494917 A ES494917 A ES 494917A ES 494917 A ES494917 A ES 494917A ES 8105699 A1 ES8105699 A1 ES 8105699A1
- Authority
- ES
- Spain
- Prior art keywords
- polypeptide
- weight
- novel
- physiologically acceptable
- following composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Endocrinology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Reinforced Plastic Materials (AREA)
Abstract
METODO DE OBTENCION DE UN POLIPEPTIDO ESPASMOLITICO PANCREATICO. SE TRITURAN GLANDULAS DE PANCREAS DE PORCINO DESENGRASADAS, EN ESTADO CONGELADO. SE RECUPERA LA INSULINA CON UNA MEZCLA DE AGUA Y UN DISOLVENTE ORGANICO MISCIBLE CON AGUA, EN UN MEDIO ACIDO. SE SEPARA EL RESIDUO DE LAS GLANDULAS POR CENTRIFUGACION. SE NEUTRALIZA EL EXTRACTO HASTA UN PH DE 5 A 9. SE CLARIFICA POR CENTRIFUGACION Y SE ACIDIFICA HASTA UN PH DE 3 A 4. SE SEPARA EL DISOLVENTE ORGANICO POR EVAPORACION A PRESION REDUCIDA. EL EXTRACTO CONCENTRADO OBTENIDO SE SALA POR ADICION DE CLORURO SODICO. SE AISLA EL POLIPEPTICO USANDO METODOS CROMATOGRAFICOS Y PRECIPITACION. SE USA PARA TRATAMIENTO DE ESPASMOS DE LA MUSCULATURA LISA Y ESTADOS DE HIPERMOTILIDAD. A
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB7931518 | 1979-09-11 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES494917A0 ES494917A0 (es) | 1981-06-16 |
| ES8105699A1 true ES8105699A1 (es) | 1981-06-16 |
Family
ID=10507754
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES494917A Expired ES8105699A1 (es) | 1979-09-11 | 1980-09-10 | Un metodo para aislar un polipeptido espasmolitico pancreatico purificado. |
Country Status (15)
| Country | Link |
|---|---|
| JP (1) | JPS609760B2 (es) |
| AT (1) | AT373149B (es) |
| AU (1) | AU537523B2 (es) |
| BE (1) | BE885199A (es) |
| CA (1) | CA1160624A (es) |
| CH (1) | CH646414A5 (es) |
| DE (1) | DE3034198A1 (es) |
| DK (1) | DK380880A (es) |
| ES (1) | ES8105699A1 (es) |
| FI (1) | FI802828A (es) |
| FR (1) | FR2464942A1 (es) |
| IT (1) | IT1195032B (es) |
| NL (1) | NL8005084A (es) |
| NO (1) | NO802683L (es) |
| SE (1) | SE8006333L (es) |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB924815A (en) * | 1959-12-24 | 1963-05-01 | Maurice Roux | Improvements in methods of preparation of polypeptides of spasmolytic activity |
-
1980
- 1980-09-08 DK DK380880A patent/DK380880A/da not_active Application Discontinuation
- 1980-09-09 NL NL8005084A patent/NL8005084A/nl not_active Application Discontinuation
- 1980-09-10 NO NO802683A patent/NO802683L/no unknown
- 1980-09-10 FR FR8019545A patent/FR2464942A1/fr active Granted
- 1980-09-10 FI FI802828A patent/FI802828A/fi not_active Application Discontinuation
- 1980-09-10 CH CH681480A patent/CH646414A5/de not_active IP Right Cessation
- 1980-09-10 SE SE8006333A patent/SE8006333L/xx not_active Application Discontinuation
- 1980-09-10 AT AT0455180A patent/AT373149B/de not_active IP Right Cessation
- 1980-09-10 ES ES494917A patent/ES8105699A1/es not_active Expired
- 1980-09-11 CA CA000360561A patent/CA1160624A/en not_active Expired
- 1980-09-11 JP JP55125375A patent/JPS609760B2/ja not_active Expired
- 1980-09-11 BE BE6/47265A patent/BE885199A/fr not_active IP Right Cessation
- 1980-09-11 IT IT24588/80A patent/IT1195032B/it active
- 1980-09-11 AU AU62317/80A patent/AU537523B2/en not_active Ceased
- 1980-09-11 DE DE19803034198 patent/DE3034198A1/de not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| FI802828A (fi) | 1981-03-12 |
| BE885199A (fr) | 1981-03-11 |
| DK380880A (da) | 1981-05-12 |
| ATA455180A (de) | 1983-05-15 |
| SE8006333L (sv) | 1981-03-12 |
| NL8005084A (nl) | 1981-03-13 |
| IT8024588A0 (it) | 1980-09-11 |
| JPS56123996A (en) | 1981-09-29 |
| JPS609760B2 (ja) | 1985-03-12 |
| FR2464942B1 (es) | 1984-10-26 |
| NO802683L (no) | 1981-05-07 |
| AU6231780A (en) | 1981-03-19 |
| DE3034198A1 (de) | 1981-04-09 |
| CA1160624A (en) | 1984-01-17 |
| IT1195032B (it) | 1988-09-28 |
| AU537523B2 (en) | 1984-06-28 |
| CH646414A5 (en) | 1984-11-30 |
| FR2464942A1 (fr) | 1981-03-20 |
| AT373149B (de) | 1983-12-27 |
| ES494917A0 (es) | 1981-06-16 |
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