ES8104273A1 - Un procedimiento para la preparacion de una ftalazina - Google Patents
Un procedimiento para la preparacion de una ftalazinaInfo
- Publication number
- ES8104273A1 ES8104273A1 ES489947A ES489947A ES8104273A1 ES 8104273 A1 ES8104273 A1 ES 8104273A1 ES 489947 A ES489947 A ES 489947A ES 489947 A ES489947 A ES 489947A ES 8104273 A1 ES8104273 A1 ES 8104273A1
- Authority
- ES
- Spain
- Prior art keywords
- phthalazine
- preparing
- processes
- pharmaceutical compositions
- compositions containing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/30—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
- C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
- C07D211/28—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms to which a second hetero atom is attached
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/40—Acylated substituent nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/42—Radicals substituted by singly-bound nitrogen atoms having hetero atoms attached to the substituent nitrogen atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
PROCEDIMIENTO PARA LA PREPARACION DE FTALAZINA, DE FORMULA GENERAL (I), O UNA SAL DE ADICION DE ACIDO FARMACEUTICAMENTE ACEPTABLE, DONDE R'' ES UN GRUPO ALQUILO; Y ES UN GRUPO DE FORMULA -(CH2)M-Z; SIENDO Z DISTINTOS TIPOS DE RADICALES; M ES 1 O 2. CONSISTE EN HACER REACCIONAR UNA FTALAZINA DE FORMULA (III), CON UNA AMINA DE FORMULA (IV), SEGUIDO OPCIONALMENTE DE REACCION DEL PRODUCTO ASI OBTENIDO CON UN ACIDO NO TOXICO PARA FORMAR UNA SAL DE ADICION DE ACIDO FARMACEUTICAMENTE ACEPTABLE. Q'' ES UN GRUPO CLORO, BROMO, YODO, ALCOXI INFERIOR O TIO. ESTE COMPUESTO TIENE APLICACION EN EL TRATAMIENTO DEL RITMO CARDIACO. *FORMULA*
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB7910843 | 1979-03-28 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES489947A0 ES489947A0 (es) | 1981-04-16 |
ES8104273A1 true ES8104273A1 (es) | 1981-04-16 |
Family
ID=10504188
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES489947A Expired ES8104273A1 (es) | 1979-03-28 | 1980-03-26 | Un procedimiento para la preparacion de una ftalazina |
ES497172A Expired ES8200103A1 (es) | 1979-03-28 | 1980-11-26 | Un procedimiento para la preparacion de una ftalazina |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES497172A Expired ES8200103A1 (es) | 1979-03-28 | 1980-11-26 | Un procedimiento para la preparacion de una ftalazina |
Country Status (13)
Country | Link |
---|---|
EP (1) | EP0017411B1 (es) |
JP (1) | JPS55130973A (es) |
AR (2) | AR224518A1 (es) |
AT (1) | ATE800T1 (es) |
AU (1) | AU518701B2 (es) |
DE (1) | DE3060253D1 (es) |
DK (1) | DK129380A (es) |
ES (2) | ES8104273A1 (es) |
FI (1) | FI800938A (es) |
GR (1) | GR67739B (es) |
IL (1) | IL59619A0 (es) |
PH (1) | PH15981A (es) |
PT (1) | PT71025A (es) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2744451B1 (fr) * | 1996-02-01 | 1998-04-24 | Pf Medicament | Nouvelles imidazolidinones, pyrimidinones, et 1,3-diazepin-2 -ones, leur preparation et leurs applications en therapeutique |
US6518423B1 (en) | 1996-08-09 | 2003-02-11 | Eisai Co., Ltd. | Benzopiperidine derivatives |
WO2012006276A1 (en) * | 2010-07-06 | 2012-01-12 | North Carolina State University | Inhibition of bacterial biofilms with aryl carbamates |
US9125408B2 (en) | 2010-09-01 | 2015-09-08 | North Carolina State University | Use of aryl carbamates in agriculture and other plant-related areas |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IN148482B (es) * | 1977-06-03 | 1981-03-07 | Pfizer | |
GB2007654B (en) * | 1977-11-03 | 1982-06-16 | Pfizer Ltd | Therapeutic agents |
GB2008104B (en) * | 1977-11-03 | 1982-03-10 | Pfizer Ltd | Therapeutic agents |
-
1980
- 1980-03-14 IL IL59619A patent/IL59619A0/xx unknown
- 1980-03-22 GR GR61520A patent/GR67739B/el unknown
- 1980-03-24 DE DE8080300909T patent/DE3060253D1/de not_active Expired
- 1980-03-24 EP EP80300909A patent/EP0017411B1/en not_active Expired
- 1980-03-24 AT AT80300909T patent/ATE800T1/de not_active IP Right Cessation
- 1980-03-25 PH PH23810A patent/PH15981A/en unknown
- 1980-03-26 DK DK129380A patent/DK129380A/da not_active IP Right Cessation
- 1980-03-26 FI FI800938A patent/FI800938A/fi not_active Application Discontinuation
- 1980-03-26 ES ES489947A patent/ES8104273A1/es not_active Expired
- 1980-03-27 PT PT71025A patent/PT71025A/pt unknown
- 1980-03-27 JP JP3963480A patent/JPS55130973A/ja active Granted
- 1980-03-27 AU AU56917/80A patent/AU518701B2/en not_active Ceased
- 1980-03-28 AR AR280444A patent/AR224518A1/es active
- 1980-11-26 ES ES497172A patent/ES8200103A1/es not_active Expired
-
1981
- 1981-06-02 AR AR285555A patent/AR223434A1/es active
Also Published As
Publication number | Publication date |
---|---|
DK129380A (da) | 1980-09-29 |
AR223434A1 (es) | 1981-08-14 |
EP0017411B1 (en) | 1982-03-31 |
FI800938A (fi) | 1980-09-29 |
AU518701B2 (en) | 1981-10-15 |
PH15981A (en) | 1983-05-16 |
ES497172A0 (es) | 1981-10-16 |
GR67739B (es) | 1981-09-16 |
IL59619A0 (en) | 1980-06-30 |
PT71025A (en) | 1980-04-01 |
ES8200103A1 (es) | 1981-10-16 |
AR224518A1 (es) | 1981-12-15 |
ATE800T1 (de) | 1982-04-15 |
ES489947A0 (es) | 1981-04-16 |
DE3060253D1 (en) | 1982-05-06 |
AU5691780A (en) | 1980-10-02 |
JPS5716111B2 (es) | 1982-04-02 |
EP0017411A1 (en) | 1980-10-15 |
JPS55130973A (en) | 1980-10-11 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES8203883A1 (es) | Un procedimiento para la preparacion de derivados de imida- zol | |
ES483767A1 (es) | Procedimiento para producir n-arilsulfonil-l-argininamidas | |
DE3271269D1 (en) | Benzimidazole derivatives, process for the preparation thereof and pharmaceutical composition containing the same | |
ES503768A0 (es) | Procedimiento de preparacion de derivados de 1-fenil-1-hi- droxi-etilamina | |
IE820200L (en) | Dichloroamino acid germicides and fungicides | |
NO167737C (no) | Analogifremgangsmaate for fremstilling av terapeutisk aktive tetrahydroimidazo(1,4)benzodiazepin-2-oner. | |
ES8200103A1 (es) | Un procedimiento para la preparacion de una ftalazina | |
DK379281A (da) | Azolylalkyl-derivater fremgangsmaade til deres fremstilling og deres anvendelse som fungicider | |
JPS5283396A (en) | Novel compound physiologically acceptable salts thereof process for preparing same and medical composition containing same | |
ES2005504A6 (es) | Un procedimiento para preparar nuevos derivados de tetrahidrofurano. | |
IL70797A0 (en) | Triazole derivatives,their preparation and pharmaceutical and agricultural compositions containing them | |
ES8103068A1 (es) | Procedimiento para la preparacion de derivados de tiazolina | |
IE40395B1 (en) | 2,3-dihydrobenzofuranyl-7-n-methylcarbamates, their preparation and their use as insecticides | |
ES8300095A1 (es) | "un procedimiento para preparar derivados de halofenil-piridil-alilamina". | |
ES8100249A1 (es) | Un metodo para la preparacion de un compuesto de acido hi- droxamico | |
ATE123487T1 (de) | Derivate der kaffeinsäure und sie enthaltende pharmazeutische zusammensetzungen. | |
SE7412163L (es) | ||
ES8304920A1 (es) | Un procedimiento para preparar derivados de n-acil-n-hidroxi-a minoacidos. | |
IE790163L (en) | Thieno-pyridines | |
SE8903313L (sv) | Nya 2-metoxikarbonyl-substituerade n,n'-di-(trimetoxibensoyl)-piperaziner, foerfarande foer framstaellning daerav och terapeutiska foereningar innehaallande dem | |
GB2007654A (en) | 6,7-Dialkoxy-4-(4-substituted piperidino)quinazolines | |
ES482083A1 (es) | Un procedimiento para la preparacion de un derivado de teta-hidro-2h-benzo-c-pirrol. | |
DE2960160D1 (en) | Thiol-phosphoric-acid-s-4-nitro-2-trichloromethylphenyl esters, their preparation and their application | |
IE33893L (en) | Insecticidal agents; substituted benzene derivatives | |
ES467316A1 (es) | Procedimiento para la obtencion de derivados de acidos metil-2 fenoxi-2 propionicos. |