ES8103757A1 - Un procedimiento para la preparacion de antibioticos de ce- falosporina - Google Patents

Un procedimiento para la preparacion de antibioticos de ce- falosporina

Info

Publication number
ES8103757A1
ES8103757A1 ES489782A ES489782A ES8103757A1 ES 8103757 A1 ES8103757 A1 ES 8103757A1 ES 489782 A ES489782 A ES 489782A ES 489782 A ES489782 A ES 489782A ES 8103757 A1 ES8103757 A1 ES 8103757A1
Authority
ES
Spain
Prior art keywords
carbamoylmethylpyridinium
compounds
formula
ceph
aminothiazol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES489782A
Other languages
English (en)
Other versions
ES489782A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of ES489782A0 publication Critical patent/ES489782A0/es
Publication of ES8103757A1 publication Critical patent/ES8103757A1/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/06Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom
    • C07D213/16Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom containing only one pyridine ring
    • C07D213/20Quaternary compounds thereof

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE ANTIBIOTICOS DE CEFALOSPORINA DE FORMULA GENERAL (I), DONDE R ELEVADO A A Y R ELEVADO A B PUEDEN SER DISTINTOS TIPOS DE RADICALES, Y ELEVADO A + REPRESENTA UN GRUPO N-CARBOMOILMETILPIRIDINIO. CONSISTE EN HACER REACCIONAR UN COMPUESTO DE FORMULA (II), CON UN NUCLEOTICO DE AZUFRE QUE SIRVE PARA FORMAR EL GRUPO -CH2SY ELEVADO A +; R ELEVADO A 2 Y R ELEVADO A 2A PUEDEN REPRESENTAR INDEPENDIENTEMENTE HIDROGENO O UN GRUPO BLOQUEANTE DEL CARBOXILO; R ELEVADO A 3 ES UN GRUPO AMINO O AMINO. ESTOS ANTIBIOTICOS PRESENTAN ACTIVIDAD ANTIBACTERIANA. *FORMULA*
ES489782A 1979-03-22 1980-03-21 Un procedimiento para la preparacion de antibioticos de ce- falosporina Expired ES8103757A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB7910088 1979-03-22
GB7932982 1979-09-24

Publications (2)

Publication Number Publication Date
ES489782A0 ES489782A0 (es) 1981-03-16
ES8103757A1 true ES8103757A1 (es) 1981-03-16

Family

ID=26270985

Family Applications (3)

Application Number Title Priority Date Filing Date
ES489781A Granted ES489781A0 (es) 1979-03-22 1980-03-21 Un procedimiento para la preparacion de antibioticos de ce- falosporina
ES489782A Expired ES8103757A1 (es) 1979-03-22 1980-03-21 Un procedimiento para la preparacion de antibioticos de ce- falosporina
ES489783A Granted ES489783A0 (es) 1979-03-22 1980-03-21 Un procedimiento para la preparacion de antibioticos de ce- falosporina

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES489781A Granted ES489781A0 (es) 1979-03-22 1980-03-21 Un procedimiento para la preparacion de antibioticos de ce- falosporina

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES489783A Granted ES489783A0 (es) 1979-03-22 1980-03-21 Un procedimiento para la preparacion de antibioticos de ce- falosporina

Country Status (18)

Country Link
US (1) US4315005A (es)
CA (1) CA1144920A (es)
CH (1) CH651574A5 (es)
DE (1) DE3011038A1 (es)
DK (1) DK123480A (es)
ES (3) ES489781A0 (es)
FI (1) FI800889A (es)
FR (1) FR2451921A1 (es)
IE (1) IE49569B1 (es)
IL (1) IL59680A (es)
IT (1) IT1143081B (es)
LU (1) LU82285A1 (es)
NL (1) NL8001673A (es)
NO (1) NO800828L (es)
NZ (1) NZ193212A (es)
PH (1) PH15777A (es)
PT (3) PT70996B (es)
SE (1) SE8002217L (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR231986A1 (es) * 1978-05-26 1985-04-30 Glaxo Group Ltd Procedimiento para preparar antibioticos de cefalosporina
ES486026A1 (es) * 1978-11-17 1980-09-01 Glaxo Group Ltd Un procedimiento para la preparacion de antibioticos de ce- falosporina
US4443444A (en) * 1980-08-11 1984-04-17 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds
GR75487B (es) * 1981-06-22 1984-07-23 Fujisawa Pharmaceutical Co
FR2516515A1 (fr) * 1981-11-16 1983-05-20 Sanofi Sa Nouveaux derives de pyridinium thiomethyl cephalosporines, procede pour leur preparation et compositions pharmaceutiques les contenant
FR2517309A1 (fr) * 1981-12-01 1983-06-03 Sanofi Sa Nouveaux derives de cephalosporines substitues en position 3 par un groupe heterocycle thiomethyl; procede de preparation desdits composes et compositions pharmaceutiques en contenant
US4616081A (en) * 1982-07-07 1986-10-07 Asahi Kasei Kogyo Kabushiki Kaisha Cephalosporin compounds
US5734047A (en) * 1995-12-20 1998-03-31 Bristol-Myers Squibb Company Cephalosporin derivatives

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4033950A (en) * 1971-05-14 1977-07-05 Glaxo Laboratories Limited 3-Hydroxymethyl-7β-(2-alkoxy-or benzyloxyimino-2-arylacetamido)ceph-3-em-4-carboxylic acids and salts thereof
US4144392A (en) * 1973-12-21 1979-03-13 Glaxo Laboratories Limited Cephalosporins having at position-7 a carboxy substituted α-etherified hydroxyimino-arylacetamido group and at position-3 the residue of a sulphur nucleophile
US4144393A (en) * 1973-12-21 1979-03-13 Glaxo Laboratories Limited 3-Acetoxymethyl cephalosporins having at position-7 a carboxy substituted α-etherified hydroxyiminoarylacetamido group
DK154939C (da) * 1974-12-19 1989-06-12 Takeda Chemical Industries Ltd Analogifremgangsmaade til fremstilling af thiazolylacetamido-cephemforbindelser eller farmaceutisk acceptable salte eller estere deraf
DE2760123C2 (de) * 1976-01-23 1986-04-30 Roussel-Uclaf, Paris 7-Aminothiazolyl-syn-oxyiminoacetamidocephalosporansäuren, ihre Herstellung und sie enthaltende pharmazeutische Zusammensetzungen
US4166115A (en) * 1976-04-12 1979-08-28 Fujisawa Pharmaceutical Co., Ltd. Syn 7-oxoimino substituted derivatives of cephalosporanic acid
DE2714880A1 (de) * 1977-04-02 1978-10-26 Hoechst Ag Cephemderivate und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
US4315005A (en) 1982-02-09
ES8103105A1 (es) 1981-02-16
IL59680A0 (en) 1980-06-30
DE3011038A1 (de) 1980-11-27
IE800593L (en) 1980-09-22
IT8048230A0 (it) 1980-03-21
IT1143081B (it) 1986-10-22
LU82285A1 (fr) 1980-10-08
CH651574A5 (de) 1985-09-30
NL8001673A (nl) 1980-09-24
FR2451921B1 (es) 1984-04-27
PT70996B (en) 1981-06-25
ES8103101A1 (es) 1981-02-16
PT70994A (en) 1980-04-01
NO800828L (no) 1980-09-23
PT70994B (en) 1982-11-22
CA1144920A (en) 1983-04-19
NZ193212A (en) 1982-12-07
ES489782A0 (es) 1981-03-16
ES489783A0 (es) 1981-02-16
PT70995B (en) 1981-06-25
IL59680A (en) 1983-07-31
DK123480A (da) 1980-09-23
FR2451921A1 (fr) 1980-10-17
IE49569B1 (en) 1985-10-30
PH15777A (en) 1983-03-24
ES489781A0 (es) 1981-02-16
PT70996A (en) 1980-04-01
FI800889A (fi) 1980-09-23
PT70995A (en) 1980-04-01
SE8002217L (sv) 1980-10-31

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19971201