ES8100077A1 - Procedimiento para preparar pastillas de glucosidos cardioactivos - Google Patents

Procedimiento para preparar pastillas de glucosidos cardioactivos

Info

Publication number
ES8100077A1
ES8100077A1 ES485399A ES485399A ES8100077A1 ES 8100077 A1 ES8100077 A1 ES 8100077A1 ES 485399 A ES485399 A ES 485399A ES 485399 A ES485399 A ES 485399A ES 8100077 A1 ES8100077 A1 ES 8100077A1
Authority
ES
Spain
Prior art keywords
tablet composition
pharmaceutical tablet
disclosed
amorphous
warm
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES485399A
Other languages
English (en)
Other versions
ES485399A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beiersdorf AG
Original Assignee
Beiersdorf AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beiersdorf AG filed Critical Beiersdorf AG
Publication of ES8100077A1 publication Critical patent/ES8100077A1/es
Publication of ES485399A0 publication Critical patent/ES485399A0/es
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/143—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)

Abstract

PROCEDIMIENTO DE OBTENCION DE PASTILLAS DE GLUCOSIDOS CARDIOACTIVOS. CONSTA DE LAS SIGUIENTES OPERACIONES: 1. DISOLUCION DE LA MATERIA ACTIVA Y EL AGENTE AGLOMERANTE CON UN DISOLVENTE ORGANICO VOLATIL MISCIBLE EN AGUA. 2. ADICION A LA DISOLUCION DE ACIDO SILICICO POROSO AMORFO, MICRODISPERSO, MANTENIENDO LA MASA EN AGITACION HASTA QUE ADQUIERA UNA ESTRUCTURA GELOSA HOMOGENEA SIN GRUMOS PRECIPITANDOSE Y FIJANDOSE LA MATERIA ACTIVA EN EL ACIDO SILICICO. 3. MEZCLA DE LA MASA CON UN MATERIAL DE RELLENO Y SOMETIMIENTO A UN ESTADO DE GRANULACION. 4. SECADO Y TAMIZADO, ADICION DE DISGREGANTES Y DESLIZANTES Y COMPRESION HASTA UNIDADES DE DOSIFICACION EN TABLETAS. R
ES485399A 1978-10-18 1979-10-17 Procedimiento para preparar pastillas de glucosidos cardioactivos Granted ES485399A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2845326A DE2845326C2 (de) 1978-10-18 1978-10-18 Verwendung einer spezifischen mikrodispersen, amorphen, porösen Kieselsäure zur Herstellung von Digoxin enthaltenden Tabletten mit stark beschleunigter Wirkstoff-Freisetzung

Publications (2)

Publication Number Publication Date
ES8100077A1 true ES8100077A1 (es) 1980-11-01
ES485399A0 ES485399A0 (es) 1980-11-01

Family

ID=6052475

Family Applications (1)

Application Number Title Priority Date Filing Date
ES485399A Granted ES485399A0 (es) 1978-10-18 1979-10-17 Procedimiento para preparar pastillas de glucosidos cardioactivos

Country Status (14)

Country Link
US (1) US4254099A (es)
JP (1) JPS5555113A (es)
AT (1) AT371712B (es)
AU (1) AU523794B2 (es)
BE (1) BE879487A (es)
CA (1) CA1125656A (es)
CH (1) CH640738A5 (es)
DE (1) DE2845326C2 (es)
ES (1) ES485399A0 (es)
FR (1) FR2439018A1 (es)
GB (1) GB2033225B (es)
NL (1) NL7907244A (es)
SE (1) SE445295B (es)
ZA (1) ZA795530B (es)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1146866A (en) * 1979-07-05 1983-05-24 Yamanouchi Pharmaceutical Co. Ltd. Process for the production of sustained release pharmaceutical composition of solid medical material
JPS56152416A (en) * 1980-04-25 1981-11-26 Tsumura Juntendo Inc Preparation of chinese herbal remedy tablet
DE3263932D1 (en) * 1981-11-28 1985-07-04 Boehringer Mannheim Gmbh Guar gum preparation forms for oral administration
US4581232A (en) * 1983-07-20 1986-04-08 Warner-Lambert Company Magnesium trisilicate suitable for preparation of medicament adsorbates
GB8413191D0 (en) * 1984-05-23 1984-06-27 Beecham Group Plc Pharmaceutical composition
US4617294A (en) * 1985-04-22 1986-10-14 Ppg Industries, Inc. Animal feed supplement
US5310572A (en) * 1987-02-03 1994-05-10 Dow Corning Corporation Process for forming a coated active agent-containing article
IT1216570B (it) * 1988-04-08 1990-03-08 Vectorpharma Int Composizione farmaceutiche a rilascio controllato e procedimento per la loro preparazione.
US5039699A (en) * 1989-03-27 1991-08-13 Lederle (Japan), Ltd. Anti-peptic ulcer agent
JPH03109332A (ja) * 1989-09-21 1991-05-09 Shiseido Co Ltd 薬剤組成物
GB9025251D0 (en) * 1990-11-20 1991-01-02 Solomon Montague C Nifedipine dosage forms
MY110880A (en) * 1991-01-30 1999-06-30 The Wellcome Foundation Ltd Water-dispersible tablets
US5629016A (en) * 1991-01-30 1997-05-13 Glaxo Wellcome Inc. Water-dispersible tablets
US5698226A (en) * 1993-07-13 1997-12-16 Glaxo Wellcome Inc. Water-dispersible tablets
JP4064476B2 (ja) * 1996-03-29 2008-03-19 エラワン ファーマスーティカル リサーチ アンドラボラトリー カンパニー リミテッド 二酸化珪素を有する球状凝集した澱粉
GB9720061D0 (en) 1997-09-19 1997-11-19 Crosfield Joseph & Sons Metal compounds as phosphate binders
CA2311734C (en) * 2000-04-12 2011-03-08 Bristol-Myers Squibb Company Flash-melt oral dosage formulation
DE60221238T2 (de) * 2001-05-01 2007-10-31 Pfizer Products Inc., Groton Herstellungsverfahren für niedrig dosierte pharmazeutische zusammensetzung
TWI324074B (en) * 2001-10-09 2010-05-01 Bristol Myers Squibb Co Flashmelt oral dosage formulation
MY142989A (en) * 2004-03-10 2011-02-14 Bayer Schering Pharma Ag Stabilised supersaturated solids of lipophilic drugs
BRPI0613611A2 (pt) * 2005-07-22 2011-01-18 Myriad Genetics Inc formulações de alta concentração de fármaco e formas de dosagens
MY157620A (en) 2006-01-31 2016-06-30 Cytochroma Dev Inc A granular material of a solid water-soluble mixed metal compound capable of binding phosphate
SG183059A1 (en) 2007-02-23 2012-08-30 Gilead Sciences Inc Modulators of pharmacokinetic properties of therapeutics
GB0714670D0 (en) * 2007-07-27 2007-09-05 Ineos Healthcare Ltd Use
GB0720220D0 (en) * 2007-10-16 2007-11-28 Ineos Healthcare Ltd Compound
PL2296633T3 (pl) * 2008-05-02 2016-03-31 Gilead Sciences Inc Zastosowanie cząsteczek stałych nośników dla udoskonalenia przetwarzalności środka farmaceutycznego
GB0913525D0 (en) 2009-08-03 2009-09-16 Ineos Healthcare Ltd Method
GB201001779D0 (en) 2010-02-04 2010-03-24 Ineos Healthcare Ltd Composition
HUE051406T2 (hu) * 2012-11-14 2021-03-01 Grace W R & Co Biológiailag aktív anyagot és rendezetlen szervetlen oxidot tartalmazó kompozíciók

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR541197A (fr) * 1920-01-08 1922-07-24 Lilly Co Eli Procédé d'enrobage de remèdes et en particulier d'alcaloîdes d'ipéca de manière à ce qu'ils puissent être administrés par la bouche et absorbés par l'intestin
US2038694A (en) * 1930-10-15 1936-04-28 Davision Chemical Corp Medicament
US2698822A (en) * 1951-04-28 1955-01-04 Fougera & Co Inc E Cardiac glycoside buccal composition
US2820741A (en) * 1954-04-29 1958-01-21 Abbott Lab Aluminum aspirin granulation and method for making
US2857313A (en) * 1956-03-27 1958-10-21 Ciba Pharm Prod Inc Self-lubricating granulation
US3034911A (en) * 1959-03-25 1962-05-15 Nat Starch Chem Corp Tablet disintegrants
BE610298A (es) * 1960-11-17
US3148124A (en) * 1962-06-12 1964-09-08 William E Gaunt Method of preparing sustained release pharmaceutical tablets
DE1228029C2 (de) * 1964-05-09 1973-05-17 Merck Ag E Verfahren zur Herstellung von Tabletten durch Pressen von Pulvergemischen ohne vorhergehende Granulation
US3400197A (en) * 1965-01-26 1968-09-03 Robins Co Inc A H Compressible sustained release pharmaceutical tablet lipid-colloidal silica gel matrix fragment granules
DE1492034A1 (de) * 1965-05-18 1969-02-20 Merck Ag E Verfahren zur Herstellung fester haltbarer Zubereitungen von empfindlichen,in Wasser schwer loeslichen Wirkstoffen,vorzugsweise Arzneimitteln
NL6906980A (es) * 1968-05-22 1969-11-25
US3696091A (en) * 1970-06-03 1972-10-03 Boehringer Sohn Ingelheim Novel cardiac-active principles of the cardenolide glycoside class
US3632778A (en) * 1970-06-10 1972-01-04 Hoffmann La Roche Tablets containing l-dopa
US3725556A (en) * 1970-11-12 1973-04-03 D Hanssen Method of manufacturing rapidly disintegrating pharmaceutical tablets
US3908003A (en) * 1971-07-02 1975-09-23 American Home Prod Enrobed solid hydrophobic tableting lubricants and compositions
US3923969A (en) * 1973-06-12 1975-12-02 Battelle Institut E V Carrier system for a drug with sustained release
US3929996A (en) * 1973-06-29 1975-12-30 Interx Research Corp Pharmaceutical compositions containing a digoxin complex
US3884905A (en) * 1974-05-02 1975-05-20 Interx Research Corp Pro-drug forms of digoxin
US3946110A (en) * 1974-05-30 1976-03-23 Peter, Strong Research And Development Company, Inc. Medicinal compositions and methods of preparing the same
US4151273A (en) * 1974-10-31 1979-04-24 The Regents Of The University Of California Increasing the absorption rate of insoluble drugs
US4013785A (en) * 1975-03-21 1977-03-22 Bristol-Myers Company Apap tablet containing fumed silica and process for manufacturing same
US4143129A (en) * 1975-10-11 1979-03-06 Lilly Industries Limited Cephalexin tablets
US4021546A (en) * 1976-03-08 1977-05-03 Interx Research Corporation Pro-drug forms of digoxin and method of preparing and using same
US4202888A (en) * 1976-07-12 1980-05-13 Kali-Chemie Pharma Gmbh. Readily enterally absorbable pharmaceutical compositions of cardiac glycosides and preparation thereof
US4147768A (en) * 1976-09-13 1979-04-03 Interx Research Corporation Enteric coated digoxin and therapeutic use thereof

Also Published As

Publication number Publication date
SE7907527L (sv) 1980-04-19
FR2439018B1 (es) 1983-03-04
AU523794B2 (en) 1982-08-12
GB2033225A (en) 1980-05-21
CH640738A5 (de) 1984-01-31
SE445295B (sv) 1986-06-16
NL7907244A (nl) 1980-04-22
DE2845326A1 (de) 1980-04-24
US4254099A (en) 1981-03-03
DE2845326C2 (de) 1985-05-23
JPS5555113A (en) 1980-04-22
AU5178979A (en) 1980-04-24
ATA675979A (de) 1982-12-15
AT371712B (de) 1983-07-25
GB2033225B (en) 1983-06-15
ZA795530B (en) 1980-09-24
FR2439018A1 (fr) 1980-05-16
ES485399A0 (es) 1980-11-01
CA1125656A (en) 1982-06-15
BE879487A (fr) 1980-02-15

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