ES553232A0 - Un metodo para preparar una formulacion liofilizada y estabilizada de gamma interferon - Google Patents

Un metodo para preparar una formulacion liofilizada y estabilizada de gamma interferon

Info

Publication number
ES553232A0
ES553232A0 ES553232A ES553232A ES553232A0 ES 553232 A0 ES553232 A0 ES 553232A0 ES 553232 A ES553232 A ES 553232A ES 553232 A ES553232 A ES 553232A ES 553232 A0 ES553232 A0 ES 553232A0
Authority
ES
Spain
Prior art keywords
freeze
preparing
gamma interferon
stabilized formulation
stabilized
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES553232A
Other languages
English (en)
Other versions
ES8705761A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp and Dohme Corp
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of ES553232A0 publication Critical patent/ES553232A0/es
Publication of ES8705761A1 publication Critical patent/ES8705761A1/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A61K38/217—IFN-gamma
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ES553232A 1985-03-25 1986-03-21 Un metodo para preparar una formulacion liofilizada y estabilizada de gamma interferon Expired ES8705761A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US71585185A 1985-03-25 1985-03-25
US74093285A 1985-06-03 1985-06-03

Publications (2)

Publication Number Publication Date
ES553232A0 true ES553232A0 (es) 1987-05-16
ES8705761A1 ES8705761A1 (es) 1987-05-16

Family

ID=27109430

Family Applications (1)

Application Number Title Priority Date Filing Date
ES553232A Expired ES8705761A1 (es) 1985-03-25 1986-03-21 Un metodo para preparar una formulacion liofilizada y estabilizada de gamma interferon

Country Status (17)

Country Link
EP (1) EP0196203A3 (es)
KR (1) KR900004799B1 (es)
CN (1) CN86101878A (es)
AU (1) AU592552B2 (es)
DK (1) DK131986A (es)
ES (1) ES8705761A1 (es)
FI (1) FI861193A (es)
GR (1) GR860758B (es)
HU (1) HU200278B (es)
IL (1) IL78231A (es)
MA (1) MA20647A1 (es)
MY (1) MY101973A (es)
NO (1) NO861139L (es)
NZ (1) NZ215563A (es)
OA (1) OA08269A (es)
PT (1) PT82249B (es)
TN (1) TNSN86042A1 (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5183746A (en) * 1986-10-27 1993-02-02 Schering Aktiengesellschaft Formulation processes for pharmaceutical compositions of recombinant β-
US5037644A (en) * 1986-10-27 1991-08-06 Cetus Corporation Pharmaceutical compositions of recombinant interleukin-2 and formulation processes
EP0284249A1 (en) * 1987-03-13 1988-09-28 Interferon Sciences, Inc. Lyophilized lymphokine composition
US5151265A (en) * 1987-11-03 1992-09-29 Genentech, Inc. Gamma interferon formulation
US5004605A (en) * 1987-12-10 1991-04-02 Cetus Corporation Low pH pharmaceutical compositions of recombinant β-interferon
CA2024046A1 (en) * 1989-09-28 1991-03-29 Alberto Ferro Stabilized leukocyte-interferons
FR2690340B1 (fr) * 1992-04-24 1995-02-24 Scr Newmed Nouveau procédé de stabilisation des préparations pharmaceutiques liquides et les compositions pharmaceutiques ainsi stabilisées en résultant.
TW249202B (es) * 1993-08-13 1995-06-11 Ciba Gerigy Corp
US20030147850A1 (en) * 2001-09-27 2003-08-07 Pomytkin Igor Anatolievich Composition and methods for potentiating therapeutic effects of interferons
CU23432B6 (es) * 2005-11-02 2009-10-16 Ct Ingenieria Genetica Biotech Formulaciones estabilizadas que contienen a los interferones gamma y alfa en proporciones potenciadoras
CN109819650A (zh) * 2017-09-25 2019-05-28 春布里泽·格奥尔基·格奥尔基耶维奇 具有抗病毒和抗细菌活性的热稳定组合物及其用途

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4480032A (en) * 1980-11-13 1984-10-30 Yabrov Alexander A Natural mixture of Type I and Type II interferons
EP0080879B1 (en) * 1981-11-28 1986-10-01 Sunstar Kabushiki Kaisha Pharmaceutical composition containing interferon in stable state
ZA83768B (en) * 1982-03-01 1983-10-26 Hoffmann La Roche Homogeneous human immune interferon and process therefor
DE3484374D1 (de) * 1983-08-04 1991-05-08 Green Cross Corp Gamma-interferonzusammensetzung.
EP0168008A3 (en) * 1984-07-10 1986-12-30 Takeda Chemical Industries, Ltd. Stable composition of gamma-interferon

Also Published As

Publication number Publication date
EP0196203A2 (en) 1986-10-01
OA08269A (fr) 1987-10-30
HUT40577A (en) 1987-01-28
IL78231A (en) 1990-07-26
NO861139L (no) 1986-09-26
CN86101878A (zh) 1986-10-29
FI861193A (fi) 1986-09-26
FI861193A0 (fi) 1986-03-21
DK131986A (da) 1986-09-26
AU592552B2 (en) 1990-01-18
NZ215563A (en) 1989-06-28
ES8705761A1 (es) 1987-05-16
PT82249A (en) 1986-04-01
KR860006982A (ko) 1986-10-06
IL78231A0 (en) 1986-07-31
DK131986D0 (da) 1986-03-21
EP0196203A3 (en) 1987-09-30
MY101973A (en) 1992-02-29
PT82249B (en) 1988-01-07
TNSN86042A1 (fr) 1990-01-01
MA20647A1 (fr) 1986-10-01
AU5502886A (en) 1986-10-02
HU200278B (en) 1990-05-28
GR860758B (en) 1986-07-21
KR900004799B1 (ko) 1990-07-06

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