ES551996A0 - Procedimiento para la obtencion de conjugados de muramilpeptidos y correspondientes estereoisomeros que se derivan de lad-manosa o d-galactosa. - Google Patents

Procedimiento para la obtencion de conjugados de muramilpeptidos y correspondientes estereoisomeros que se derivan de lad-manosa o d-galactosa.

Info

Publication number
ES551996A0
ES551996A0 ES551996A ES551996A ES551996A0 ES 551996 A0 ES551996 A0 ES 551996A0 ES 551996 A ES551996 A ES 551996A ES 551996 A ES551996 A ES 551996A ES 551996 A0 ES551996 A0 ES 551996A0
Authority
ES
Spain
Prior art keywords
muramilpeptides
galactosa
manosa
lad
conjugates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES551996A
Other languages
English (en)
Other versions
ES8801309A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of ES551996A0 publication Critical patent/ES551996A0/es
Publication of ES8801309A1 publication Critical patent/ES8801309A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/001—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure
    • C07K9/005—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure containing within the molecule the substructure with m, n > 0 and m+n > 0, A, B, D, E being heteroatoms; X being a bond or a chain, e.g. muramylpeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Steroid Compounds (AREA)
ES551996A 1984-05-29 1986-02-14 Procedimiento para la obtencion de conjugados de muramilpeptidos y correspondientes estereoisomeros que se derivan de lad-manosa o d-galactosa. Expired ES8801309A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH263584 1984-05-29

Publications (2)

Publication Number Publication Date
ES551996A0 true ES551996A0 (es) 1987-12-16
ES8801309A1 ES8801309A1 (es) 1987-12-16

Family

ID=4238188

Family Applications (5)

Application Number Title Priority Date Filing Date
ES543519A Expired ES8609353A1 (es) 1984-05-29 1985-05-27 Procedimiento para la obtencion de un derivado del azucar
ES551994A Expired ES8800693A1 (es) 1984-05-29 1986-02-14 Procedimiento para la obtencion de conjugados de muramilpeptidos y correspondientes estereoisomeros que se derivan de la d-manosa o d-galactosa.
ES551996A Expired ES8801309A1 (es) 1984-05-29 1986-02-14 Procedimiento para la obtencion de conjugados de muramilpeptidos y correspondientes estereoisomeros que se derivan de lad-manosa o d-galactosa.
ES551993A Expired ES8800692A1 (es) 1984-05-29 1986-02-14 Procedimiento para la obtencion de conjugados de muramilpeptidos y correspondientes esteroisomeros que se derivan de la d-manosa o d-galactosa.
ES551995A Expired ES8800694A1 (es) 1984-05-29 1986-02-14 Procedimiento para la obtencion de conjugados de muramilpeptidos y correspondientes estereoisomeros que se derivan de la d-manosa o d-galactosa.

Family Applications Before (2)

Application Number Title Priority Date Filing Date
ES543519A Expired ES8609353A1 (es) 1984-05-29 1985-05-27 Procedimiento para la obtencion de un derivado del azucar
ES551994A Expired ES8800693A1 (es) 1984-05-29 1986-02-14 Procedimiento para la obtencion de conjugados de muramilpeptidos y correspondientes estereoisomeros que se derivan de la d-manosa o d-galactosa.

Family Applications After (2)

Application Number Title Priority Date Filing Date
ES551993A Expired ES8800692A1 (es) 1984-05-29 1986-02-14 Procedimiento para la obtencion de conjugados de muramilpeptidos y correspondientes esteroisomeros que se derivan de la d-manosa o d-galactosa.
ES551995A Expired ES8800694A1 (es) 1984-05-29 1986-02-14 Procedimiento para la obtencion de conjugados de muramilpeptidos y correspondientes estereoisomeros que se derivan de la d-manosa o d-galactosa.

Country Status (16)

Country Link
US (1) US4711879A (es)
EP (1) EP0163286A3 (es)
JP (1) JPS6198A (es)
AU (1) AU585230B2 (es)
CA (1) CA1262015A (es)
DD (1) DD232921A5 (es)
DK (1) DK236585A (es)
ES (5) ES8609353A1 (es)
FI (1) FI852105A7 (es)
GR (1) GR851293B (es)
HU (1) HUT38368A (es)
IL (1) IL75329A (es)
NO (1) NO852119L (es)
NZ (1) NZ212228A (es)
PT (1) PT80531B (es)
ZA (1) ZA853989B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5100807A (en) * 1987-10-19 1992-03-31 Abbott Laboratories Phenylacetylglutamine (pag) analytical test
US4833230A (en) * 1988-06-21 1989-05-23 Research Corporation Technologies, Inc. Polyhydroxypolyamides and process for making same
US5466680A (en) * 1992-03-26 1995-11-14 Cytologics, Inc. Method and compositions for enhancing white blood cell functioning on a mucosal or cutaneous surface
CA3021645A1 (en) 2016-04-29 2017-11-02 Icahn School Of Medicine At Mount Sinai Targeting the innate immune system to induce long-term tolerance and to resolve macrophage accumulation in atherosclerosis
CN109678751A (zh) * 2019-01-07 2019-04-26 广州同隽医药科技有限公司 一种含有二苯甲烷结构的化合物
AU2022239614A1 (en) 2021-03-19 2023-10-12 Icahn School Of Medicine At Mount Sinai Compounds for regulating trained immunity, and their methods of use

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4082736A (en) * 1976-04-26 1978-04-04 Syntex (U.S.A.) Inc. Novel immunological adjuvant compounds and methods of preparation thereof
US4082735A (en) * 1976-04-26 1978-04-04 Syntex (U.S.A.) Inc. Novel immunological adjuvant compounds and methods of preparation thereof
FR2442241A2 (fr) * 1978-03-20 1980-06-20 Anvar Nouveaux composes esters de muramyl-peptide, leur preparation et les compositions pharmaceutiques les contenant, notamment sous forme de liposomes
US4256735A (en) * 1979-01-29 1981-03-17 Merck & Co., Inc. Immunologically active dipeptidyl saccharides and methods of preparation
JPS55111499A (en) * 1979-02-21 1980-08-28 Takeda Chem Ind Ltd Glucosamine derivative and its preparation
CA1185237A (en) * 1979-02-28 1985-04-09 Yuichi Yamamura 6-deoxyglucosamine-peptide derivatives, their production and use
US4406889A (en) * 1980-02-15 1983-09-27 Ciba-Geigy Corporation Derivatives of aldohexoses, intermediates, processes for their manufacture, preparations containing such compounds, and their use
US4368190A (en) * 1980-04-17 1983-01-11 Merck & Co., Inc. Immunologically active dipeptidyl 4-O-,6-O-acyl-2-amino-2-deoxy-D-glucose derivatives and methods for their preparation
US4315913A (en) * 1980-06-09 1982-02-16 Merck & Co. Inc. Immunologically active dipeptidyl 2-amino-1,2-dideoxy-D-glucose derivatives and methods of preparation
FI79330C (fi) * 1982-07-23 1989-12-11 Ciba Geigy Ag Foerfarande foer framstaellning av farmakologiskt verkande muramylpeptid-n-(2-fosfatidyloxietyl)-amider.
US4640911A (en) * 1985-05-29 1987-02-03 Ciba-Geigy Corporation Acylated sugar derivatives, processes for their manufacture, and their use

Also Published As

Publication number Publication date
NO852119L (no) 1985-12-02
ES8800692A1 (es) 1987-11-16
IL75329A (en) 1990-04-29
ES551994A0 (es) 1987-11-16
FI852105L (fi) 1985-11-30
ES8800694A1 (es) 1987-11-16
ES543519A0 (es) 1986-09-01
NZ212228A (en) 1988-10-28
FI852105A0 (fi) 1985-05-27
AU585230B2 (en) 1989-06-15
DK236585D0 (da) 1985-05-28
HUT38368A (en) 1986-05-28
PT80531A (de) 1985-06-01
ES551993A0 (es) 1987-11-16
ES8800693A1 (es) 1987-11-16
ES8609353A1 (es) 1986-09-01
ES551995A0 (es) 1987-11-16
CA1262015A (en) 1989-09-26
DK236585A (da) 1985-11-30
ZA853989B (en) 1986-01-29
EP0163286A3 (de) 1987-12-09
ES8801309A1 (es) 1987-12-16
AU4312785A (en) 1985-12-05
DD232921A5 (de) 1986-02-12
IL75329A0 (en) 1985-09-29
US4711879A (en) 1987-12-08
PT80531B (de) 1987-04-06
FI852105A7 (fi) 1985-11-30
GR851293B (es) 1985-11-25
JPS6198A (ja) 1986-01-06
EP0163286A2 (de) 1985-12-04

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Legal Events

Date Code Title Description
MM4A Patent lapsed

Effective date: 19960506