ES525441A0 - Procedimiento para preparar derivados de acidos isoquinolein-4-carboxilicos - Google Patents

Procedimiento para preparar derivados de acidos isoquinolein-4-carboxilicos

Info

Publication number
ES525441A0
ES525441A0 ES525441A ES525441A ES525441A0 ES 525441 A0 ES525441 A0 ES 525441A0 ES 525441 A ES525441 A ES 525441A ES 525441 A ES525441 A ES 525441A ES 525441 A0 ES525441 A0 ES 525441A0
Authority
ES
Spain
Prior art keywords
carboxylic acid
acid derivatives
isoquinolein
preparing
procedure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES525441A
Other languages
English (en)
Spanish (es)
Other versions
ES8404852A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Publication of ES8404852A1 publication Critical patent/ES8404852A1/es
Publication of ES525441A0 publication Critical patent/ES525441A0/es
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/26Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
ES525441A 1982-09-09 1983-09-07 Procedimiento para preparar derivados de acidos isoquinolein-4-carboxilicos Granted ES525441A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19823233424 DE3233424A1 (de) 1982-09-09 1982-09-09 Isochinolinderivate, verfahren zu ihrer herstellung, pharmazeutische praeparate auf basis dieser verbindungen und ihre verwendung

Publications (2)

Publication Number Publication Date
ES8404852A1 ES8404852A1 (es) 1984-05-16
ES525441A0 true ES525441A0 (es) 1984-05-16

Family

ID=6172780

Family Applications (1)

Application Number Title Priority Date Filing Date
ES525441A Granted ES525441A0 (es) 1982-09-09 1983-09-07 Procedimiento para preparar derivados de acidos isoquinolein-4-carboxilicos

Country Status (19)

Country Link
US (1) US4673682A (en, 2012)
EP (1) EP0105210B1 (en, 2012)
JP (1) JPS5967270A (en, 2012)
KR (1) KR840006206A (en, 2012)
AT (1) ATE25679T1 (en, 2012)
AU (1) AU1891683A (en, 2012)
CA (1) CA1211445A (en, 2012)
DE (2) DE3233424A1 (en, 2012)
DK (1) DK408083A (en, 2012)
ES (1) ES525441A0 (en, 2012)
FI (1) FI833200A7 (en, 2012)
GR (1) GR79382B (en, 2012)
HU (1) HU191094B (en, 2012)
IL (1) IL69683A0 (en, 2012)
NO (1) NO833217L (en, 2012)
NZ (1) NZ205513A (en, 2012)
PH (1) PH18186A (en, 2012)
PT (1) PT77309B (en, 2012)
ZA (1) ZA836663B (en, 2012)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4956371A (en) * 1989-09-19 1990-09-11 Euroceltique, S.A. Substituted isoquinolines and methods of using same
DK0590455T3 (da) * 1992-09-28 2001-01-22 Hoechst Ag Antiarrytmiske og cardioprotektive substiuerede 1(2H)-isoquinoliner, fremgangsmåde til deres fremstilling, lægemiddel indeh
US5552412A (en) * 1995-01-09 1996-09-03 Pfizer Inc 5-substitued-6-cyclic-5,6,7,8-tetrahydronaphthalen2-ol compounds which are useful for treating osteoporosis
AU2004245552B2 (en) 2003-06-06 2010-01-21 Fibrogen, Inc. Nitrogen-containing heteroaryl compounds and their use in increasing endogenous erythropoietin
RU2457204C2 (ru) 2006-01-27 2012-07-27 Файброджен, Инк. Цианоизохинолиновые соединения (варианты), фармацевтическая композиция на их основе, способ ингибирования активности гидроксилазы гипоксия-индуцибельного фактора (hif) и способ лечения и/или профилактики состояния, связанного с hif, и/или состояния, связанного с эритропоэтином, и/или анемии
MX2008012734A (es) * 2006-04-04 2009-01-29 Fibrogen Inc Compuestos pirrolo- y tiazolo-piridina como moduladores del factor inducible de hipoxia (hif).
JP5649584B2 (ja) 2008-11-14 2015-01-07 フィブロジェン インコーポレイテッド Hifヒドロキシラーゼ阻害剤としてのチオクロメン誘導体
CN104470899B (zh) 2012-03-09 2017-12-26 菲布罗根有限公司 作为hif羟化酶抑制剂的4‑羟基‑异喹啉化合物
US8883823B2 (en) 2012-07-16 2014-11-11 Fibrogen, Inc. Crystalline forms of a prolyl hydroxylase inhibitor
CN114409596A (zh) 2012-07-16 2022-04-29 菲布罗根有限公司 脯氨酰羟化酶抑制剂的晶体形态
MY171483A (en) 2012-07-16 2019-10-15 Fibrogen Inc Process for making isoquinoline compounds
SG11201505748UA (en) 2013-01-24 2015-08-28 Fibrogen Inc Crystalline forms of {[1-cyano-5-(4-chlorophenoxy)-4-hydroxy-isoquinoline-3-carbonyl]-amino}-acetic acid

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2054482B1 (en, 2012) * 1969-07-11 1973-06-08 Anvar
FR2424270A1 (fr) * 1978-04-24 1979-11-23 Rhone Poulenc Ind Nouveaux derives de l'isoquinoleine, leur preparation et les compositions qui les contiennent
DE2818423A1 (de) * 1978-04-27 1979-11-08 Hoechst Ag Neue isochinolinderivate und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
JPS5967270A (ja) 1984-04-16
FI833200A7 (fi) 1984-03-10
FI833200A0 (fi) 1983-09-07
KR840006206A (ko) 1984-11-22
EP0105210B1 (de) 1987-03-04
EP0105210A2 (de) 1984-04-11
US4673682A (en) 1987-06-16
IL69683A0 (en) 1983-12-30
ES8404852A1 (es) 1984-05-16
HU191094B (en) 1987-01-28
DK408083A (da) 1984-03-10
DE3233424A1 (de) 1984-03-15
DE3369983D1 (en) 1987-04-09
EP0105210A3 (en) 1984-10-10
GR79382B (en, 2012) 1984-10-22
NO833217L (no) 1984-03-12
DK408083D0 (da) 1983-09-08
ATE25679T1 (de) 1987-03-15
PH18186A (en) 1985-04-12
PT77309A (de) 1983-10-01
PT77309B (de) 1986-04-18
AU1891683A (en) 1984-03-15
CA1211445A (en) 1986-09-16
NZ205513A (en) 1986-05-09
ZA836663B (en) 1984-04-25

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