ES521692A0 - Un procedimiento para la preparacion de (-)-(r)-1-hidroxi-2--(r-1-metil-3-fenilpropril-aminoetil-salicilamida o una sal de adicion de acido respectiva. - Google Patents

Un procedimiento para la preparacion de (-)-(r)-1-hidroxi-2--(r-1-metil-3-fenilpropril-aminoetil-salicilamida o una sal de adicion de acido respectiva.

Info

Publication number
ES521692A0
ES521692A0 ES521692A ES521692A ES521692A0 ES 521692 A0 ES521692 A0 ES 521692A0 ES 521692 A ES521692 A ES 521692A ES 521692 A ES521692 A ES 521692A ES 521692 A0 ES521692 A0 ES 521692A0
Authority
ES
Spain
Prior art keywords
phenylpropril
salicilamide
hydroxy
methyl
procedure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES521692A
Other languages
English (en)
Other versions
ES8501736A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp and Dohme LLC
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of ES8501736A1 publication Critical patent/ES8501736A1/es
Publication of ES521692A0 publication Critical patent/ES521692A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
ES521692A 1982-04-26 1983-04-21 Un procedimiento para la preparacion de (-)-(r)-1-hidroxi-2--(r-1-metil-3-fenilpropril-aminoetil-salicilamida o una sal de adicion de acido respectiva. Granted ES521692A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/371,622 US4658060A (en) 1982-04-26 1982-04-26 Preparation of (-)-5-(beta)-1-hydroxy-2-((beta)-1-methyl-3-phenylpropyl)aminoethyl) salicylamide

Publications (2)

Publication Number Publication Date
ES8501736A1 ES8501736A1 (es) 1984-12-01
ES521692A0 true ES521692A0 (es) 1984-12-01

Family

ID=23464714

Family Applications (1)

Application Number Title Priority Date Filing Date
ES521692A Granted ES521692A0 (es) 1982-04-26 1983-04-21 Un procedimiento para la preparacion de (-)-(r)-1-hidroxi-2--(r-1-metil-3-fenilpropril-aminoetil-salicilamida o una sal de adicion de acido respectiva.

Country Status (12)

Country Link
US (1) US4658060A (es)
EP (1) EP0092787B1 (es)
JP (1) JPS58194847A (es)
CA (1) CA1248967A (es)
CY (1) CY1470A (es)
DE (1) DE3365572D1 (es)
DK (1) DK174383A (es)
ES (1) ES521692A0 (es)
HK (1) HK36289A (es)
HU (1) HU191520B (es)
IE (1) IE54861B1 (es)
SG (1) SG78288G (es)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4950783A (en) * 1978-09-20 1990-08-21 Schering Corporation Treatment of hypertension
GB2181330B (en) * 1985-09-26 1990-05-09 Toshiba Kk X-ray inspection apparatus
JPH066565B2 (ja) * 1986-07-21 1994-01-26 山之内製薬株式会社 光学活性なベンゼンスルホンアミド誘導体の製造法
US4996361A (en) * 1987-07-30 1991-02-26 The University Of British Columbia Process for the preparation of optically active secondary arylamines
US4788183A (en) * 1987-11-30 1988-11-29 Schering Corporation Method for treatment of dyslipidemia in humans
US4879233A (en) * 1989-02-10 1989-11-07 Schering Corporation Novel Aspergillus niveus microorganism used for the chiral reduction of carbonyl groups
JP2818958B2 (ja) * 1990-02-23 1998-10-30 塩野義製薬株式会社 ４―（４―アルコキシフェニル）―２―ブチルアミン誘導体およびその製造法
US6011068A (en) * 1991-08-23 2000-01-04 Nps Pharmaceuticals, Inc. Calcium receptor-active molecules
US5858684A (en) * 1991-08-23 1999-01-12 The Brigham And Women's Hospital, Inc. Method of screening calcium receptor-active molecules
US6031003A (en) * 1991-08-23 2000-02-29 Nps Pharmaceuticals, Inc. Calcium receptor-active molecules
US6313146B1 (en) 1991-08-23 2001-11-06 Nps Pharmaceuticals, Inc. Calcium receptor-active molecules
US6001884A (en) * 1991-08-23 1999-12-14 Nps Pharmaceuticals, Inc. Calcium receptor-active molecules
US5688938A (en) * 1991-08-23 1997-11-18 The Brigham & Women's Hospital, Inc. Calcium receptor-active molecules
US5763569A (en) * 1991-08-23 1998-06-09 The Brigham And Women's Hospital, Inc Calcium receptor-active molecules
US5962314A (en) * 1993-02-23 1999-10-05 Nps Pharmaceuticals, Inc. Calcium receptor-active molecules
US5468865A (en) * 1994-05-03 1995-11-21 Celgene Corporation Stereopreferential synthesis of 3-(1-phenylprop-2-yl)-5-phenyloxazolidinones
NZ297157A (en) 1994-10-21 1999-08-30 Nps Pharma Inc Amine derivatives with calcium ion receptor activity; medicaments containing such compounds
AU731146C (en) 1996-05-01 2005-02-03 Nps Pharmaceuticals, Inc. Inorganic ion receptor-active compounds
EP1770083B1 (en) * 1996-05-01 2009-04-29 Nps Pharmaceuticals, Inc. Inorganic ion receptor-active compounds
CN113698316B (zh) * 2021-09-03 2022-04-19 安徽美致诚药业有限公司 一种盐酸拉贝洛尔的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4101579A (en) * 1969-02-06 1978-07-18 Allen & Hanburys Limited Phenethanolamine ethers
US4012444A (en) * 1969-07-08 1977-03-15 Allen & Hanburys Limited 5-[1-Hydroxy-2-(1-methyl-3-phenylpropyl)aminoethyl] salicylamide and physiologically acceptable acid addition salts thereof
US4137328A (en) * 1970-07-18 1979-01-30 Pfizer Inc. Phenyl-alkanolamine, alkylamine and α-aminoalkyl ketone derivatives as heart stimulants
US4000197A (en) * 1973-07-23 1976-12-28 The University Of Iowa Research Foundation Asymmetric synthesis of phenylisopropylamines
LU74760A1 (es) * 1975-04-17 1977-02-04
US4173583A (en) * 1975-04-17 1979-11-06 Schering Corporation Diastereoisomers of 5-(1-hydroxy-2-(1-methyl-3-phenylpropylamino)ethyl)salicylamide
ZA794872B (en) * 1978-09-20 1980-11-26 Schering Corp A phenylalkylaminoethylsalicylamide,its preparation and pharmaceutical compositions containing it

Also Published As

Publication number Publication date
CA1248967A (en) 1989-01-17
HK36289A (en) 1989-05-12
JPS58194847A (ja) 1983-11-12
US4658060A (en) 1987-04-14
DK174383D0 (da) 1983-04-21
DE3365572D1 (en) 1986-10-02
EP0092787A1 (en) 1983-11-02
HU191520B (en) 1987-03-30
EP0092787B1 (en) 1986-08-27
IE54861B1 (en) 1990-02-28
ES8501736A1 (es) 1984-12-01
SG78288G (en) 1989-03-23
IE830920L (en) 1983-10-26
DK174383A (da) 1983-10-27
CY1470A (en) 1989-07-21

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