NZ210420A
(en)
*
|
1983-12-06 |
1988-04-29 |
Merrell Dow Pharma |
D-amino acid oxidase substrates and pharmaceutical compositions
|
US4595656A
(en)
*
|
1984-01-06 |
1986-06-17 |
Becton Dickinson & Company |
Coupling agents and products produced therefrom
|
US4670406A
(en)
*
|
1984-01-06 |
1987-06-02 |
Becton Dickinson And Company |
Tracers for use in assays
|
US4530786A
(en)
*
|
1984-09-04 |
1985-07-23 |
Colorado State University Research Foundation |
Antibody for the detection and quantification of atrazine
|
DE3628795A1
(de)
*
|
1986-08-25 |
1988-03-03 |
Hoechst Ag |
Neue thyroninderivate
|
ATE154364T1
(de)
|
1988-09-02 |
1997-06-15 |
Univ Rockefeller |
Makrophagenabgeleiteter entzündungsmediator(mip- 2)
|
US5767227A
(en)
*
|
1989-11-03 |
1998-06-16 |
Lotus Biochemical Corp. |
Iodothyronine polymers
|
US5567594A
(en)
*
|
1991-04-26 |
1996-10-22 |
Enteron, L.P. |
Methods and compositions for the detection and treatment of diseases associated with antigens of microorganisms
|
US6190864B1
(en)
*
|
1991-05-08 |
2001-02-20 |
Chiron Corporation |
HCV genomic sequences for diagnostics and therapeutics
|
US5527709A
(en)
*
|
1992-06-26 |
1996-06-18 |
Johnson & Johnson Clinical Diagnostics, Inc. |
Immunoassays with labeled thyronine hapten analogues
|
US5273885A
(en)
*
|
1992-07-31 |
1993-12-28 |
Syntex (U.S.A.) Inc. |
Conjugates of monophenyl thyroid analogs useful in assays
|
DE69433160T2
(de)
|
1993-05-12 |
2004-07-08 |
Chiron Corp. (N.D.Ges.D. Staates Delaware), Emeryville |
Konserviertes Motiv der Hepatitis C Virus E2/NS1 Region
|
KR100361933B1
(ko)
*
|
1993-09-08 |
2003-02-14 |
라 졸라 파마슈티칼 컴파니 |
화학적으로정의된비중합성결합가플랫폼분자및그것의콘주게이트
|
US6001968A
(en)
*
|
1994-08-17 |
1999-12-14 |
The Rockefeller University |
OB polypeptides, modified forms and compositions
|
US6048837A
(en)
*
|
1994-08-17 |
2000-04-11 |
The Rockefeller University |
OB polypeptides as modulators of body weight
|
US6124439A
(en)
*
|
1994-08-17 |
2000-09-26 |
The Rockefeller University |
OB polypeptide antibodies and method of making
|
US6309853B1
(en)
|
1994-08-17 |
2001-10-30 |
The Rockfeller University |
Modulators of body weight, corresponding nucleic acids and proteins, and diagnostic and therapeutic uses thereof
|
US6124448A
(en)
*
|
1994-08-17 |
2000-09-26 |
The Rockfeller University |
Nucleic acid primers and probes for the mammalian OB gene
|
US6471956B1
(en)
|
1994-08-17 |
2002-10-29 |
The Rockefeller University |
Ob polypeptides, modified forms and compositions thereto
|
US6350730B1
(en)
|
1994-08-17 |
2002-02-26 |
The Rockefeller University |
OB polypeptides and modified forms as modulators of body weight
|
US7541151B2
(en)
|
1997-06-05 |
2009-06-02 |
Duke University |
Single-cell biosensor for the measurement of GPCR ligands in a test sample
|
US5891646A
(en)
*
|
1997-06-05 |
1999-04-06 |
Duke University |
Methods of assaying receptor activity and constructs useful in such methods
|
US6528271B1
(en)
*
|
1997-06-05 |
2003-03-04 |
Duke University |
Inhibition of βarrestin mediated effects prolongs and potentiates opioid receptor-mediated analgesia
|
ES2289796T3
(es)
|
1997-12-11 |
2008-02-01 |
University Of Saskatchewan |
Virus del sindrome del desmedro post-destete procedente de cerdos.
|
EP1816200B1
(en)
|
1997-12-11 |
2016-03-09 |
Merial |
Postweaning multisystemic wasting syndrome virus for pigs
|
US6087128A
(en)
|
1998-02-12 |
2000-07-11 |
Ndsu Research Foundation |
DNA encoding an avian E. coli iss
|
US6369201B1
(en)
|
1998-02-19 |
2002-04-09 |
Metamorphix International, Inc. |
Myostatin multimers
|
US6773911B1
(en)
|
1998-11-23 |
2004-08-10 |
Amgen Canada Inc. |
Apoptosis-inducing factor
|
EP1154793B1
(en)
|
1999-02-26 |
2010-09-15 |
Novartis Vaccines and Diagnostics, Inc. |
Use of bioadhesives and adjuvants for the mucosal delivery of antigens
|
US7018654B2
(en)
*
|
1999-03-05 |
2006-03-28 |
New River Pharmaceuticals Inc. |
Pharmaceutical composition containing an active agent in an amino acid copolymer structure
|
US6716452B1
(en)
|
2000-08-22 |
2004-04-06 |
New River Pharmaceuticals Inc. |
Active agent delivery systems and methods for protecting and administering active agents
|
US7060708B2
(en)
*
|
1999-03-10 |
2006-06-13 |
New River Pharmaceuticals Inc. |
Active agent delivery systems and methods for protecting and administering active agents
|
US6399759B1
(en)
|
1999-05-27 |
2002-06-04 |
University Of Georgia Research Foundation, Inc. |
Ant proteases and methods of inhibition
|
EP1903107A1
(en)
|
1999-09-24 |
2008-03-26 |
Cybios LLC |
Pluripotent embryonic-like stem cells, compositions, methods and uses thereof
|
US6627660B1
(en)
|
1999-11-16 |
2003-09-30 |
New River Pharmaceuticals Inc. |
Stabilized thyroxine compounds
|
DE19957065B4
(de)
|
1999-11-26 |
2005-01-05 |
Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. |
Screening-Verfahren für Arzneistoffe
|
ES2283343T3
(es)
*
|
1999-12-23 |
2007-11-01 |
Kirin Beer Kabushiki Kaisha |
Metodos y materiales relacionados con polipeptidos y polinucleotidos similares al factor de crecimiento de celulas madre.
|
US20020064861A1
(en)
*
|
2000-01-11 |
2002-05-30 |
Barletta Raul G. |
Identification of virulence determinants
|
AU2001227385A1
(en)
|
2000-01-21 |
2001-07-31 |
Hyseq, Inc. |
Methods and materials relating to stem cell growth factor-like poypeptides and polynucleotides
|
ES2609494T3
(es)
|
2000-05-10 |
2017-04-20 |
Mayo Foundation For Medical Education And Research |
Anticuerpos IgM humanos con la capacidad de inducir remielinización y usos diagnósticos y terapéuticos de los mismos, particularmente en el sistema nervioso central
|
EP1734050A3
(en)
|
2000-06-12 |
2012-12-05 |
University Of Saskatchewan |
Immunization of dairy cattle with GapC protein against streptococcus infection
|
US20020099013A1
(en)
*
|
2000-11-14 |
2002-07-25 |
Thomas Piccariello |
Active agent delivery systems and methods for protecting and administering active agents
|
US7163918B2
(en)
|
2000-08-22 |
2007-01-16 |
New River Pharmaceuticals Inc. |
Iodothyronine compositions
|
US7163800B2
(en)
*
|
2000-11-03 |
2007-01-16 |
Molecular Devices Corporation |
Methods of screening compositions for G protein-coupled receptor desensitization inhibitory activity
|
US20050136431A1
(en)
*
|
2000-11-03 |
2005-06-23 |
Oakley Robert H. |
Methods of screening compositions for G protein-coupled receptor desensitization inhibitory activity
|
US7018812B2
(en)
|
2000-11-03 |
2006-03-28 |
Duke University |
Modified G-protein coupled receptors
|
US8394813B2
(en)
*
|
2000-11-14 |
2013-03-12 |
Shire Llc |
Active agent delivery systems and methods for protecting and administering active agents
|
WO2002051868A2
(en)
*
|
2000-12-23 |
2002-07-04 |
Kirin Beer Kabushiki Kaisha |
Methods and materials relating to stem cell growth factor-like polypeptides and polynucleotides
|
US6673904B2
(en)
|
2000-12-23 |
2004-01-06 |
Kirin Beer Kabushiki Kaisha |
Stem cell growth factor-like polypeptides
|
US20100056762A1
(en)
|
2001-05-11 |
2010-03-04 |
Old Lloyd J |
Specific binding proteins and uses thereof
|
US20110313230A1
(en)
|
2001-05-11 |
2011-12-22 |
Terrance Grant Johns |
Specific binding proteins and uses thereof
|
WO2002092771A2
(en)
|
2001-05-11 |
2002-11-21 |
Ludwig Institute For Cancer Research |
Specific binding proteins and uses thereof
|
US20090324612A1
(en)
*
|
2001-06-05 |
2009-12-31 |
Kaufman Daniel L |
Modulating neuronal outgrowth via the major histocompatibility complex class i (mhc i) molecule
|
WO2002099069A2
(en)
*
|
2001-06-05 |
2002-12-12 |
The Regents Of The University Of California |
Modulating neuronal outgrowth via the major histocompatibility complex class i (mhc i) molecule
|
US7338939B2
(en)
*
|
2003-09-30 |
2008-03-04 |
New River Pharmaceuticals Inc. |
Abuse-resistant hydrocodone compounds
|
US7169752B2
(en)
|
2003-09-30 |
2007-01-30 |
New River Pharmaceuticals Inc. |
Compounds and compositions for prevention of overdose of oxycodone
|
US7375082B2
(en)
*
|
2002-02-22 |
2008-05-20 |
Shire Llc |
Abuse-resistant hydrocodone compounds
|
US20060014697A1
(en)
|
2001-08-22 |
2006-01-19 |
Travis Mickle |
Pharmaceutical compositions for prevention of overdose or abuse
|
US20070066537A1
(en)
*
|
2002-02-22 |
2007-03-22 |
New River Pharmaceuticals Inc. |
Compounds and compositions for prevention of overdose of oxycodone
|
AU2003201159A1
(en)
|
2002-01-08 |
2003-07-24 |
Bayer Healthcare Ag |
Single nucleotide polymorphisms predicting cardiovascular disease and medication efficacy
|
US7700561B2
(en)
|
2002-02-22 |
2010-04-20 |
Shire Llc |
Abuse-resistant amphetamine prodrugs
|
US7659253B2
(en)
*
|
2002-02-22 |
2010-02-09 |
Shire Llc |
Abuse-resistant amphetamine prodrugs
|
EP2319540A1
(en)
*
|
2002-02-22 |
2011-05-11 |
Shire LLC |
Sustained release pharmaceutical compounds to prevent abuse of controlled substances
|
US7105486B2
(en)
*
|
2002-02-22 |
2006-09-12 |
New River Pharmaceuticals Inc. |
Abuse-resistant amphetamine compounds
|
US20030182669A1
(en)
*
|
2002-03-19 |
2003-09-25 |
Rockman Howard A. |
Phosphoinositide 3-kinase mediated inhibition of GPCRs
|
US7290215B2
(en)
*
|
2002-06-03 |
2007-10-30 |
Microsoft Corporation |
Dynamic wizard interface system and method
|
EP2371955A1
(en)
|
2002-09-26 |
2011-10-05 |
K.U. Leuven Research & Development |
Integrase cofactor
|
AU2002953431A0
(en)
*
|
2002-12-19 |
2003-01-09 |
Murdoch University |
BmpB Novel Nucleotide and Amino Acid Sequences and Diagnostic and Therapeutic Uses Thereof
|
US7615610B2
(en)
*
|
2003-01-24 |
2009-11-10 |
Duke University |
Modified trafficking patterns for arrestin and G-protein-coupled receptors via arrestin-ubiquitin chimera
|
ES2380622T5
(es)
*
|
2003-05-29 |
2018-05-30 |
Shire Llc |
Compuestos de anfetamina resistentes al abuso
|
US20060035242A1
(en)
|
2004-08-13 |
2006-02-16 |
Michelitsch Melissa D |
Prion-specific peptide reagents
|
CA2540678C
(en)
*
|
2003-09-30 |
2011-02-22 |
New River Pharmaceuticals Inc. |
Pharmaceutical compositions for prevention of overdose or abuse
|
US7767792B2
(en)
|
2004-02-20 |
2010-08-03 |
Ludwig Institute For Cancer Research Ltd. |
Antibodies to EGF receptor epitope peptides
|
AR053385A1
(es)
|
2005-05-12 |
2007-05-02 |
Novartis Ag |
Genes y proteinas novedosos de brachyspira hyodysenteriae y uso de los mismos para diagnostico y terapia
|
US7780969B2
(en)
*
|
2005-07-15 |
2010-08-24 |
University Of Georgia Research Foundation, Inc. |
Trypanosoma cruzi proteome compositions and methods
|
US7455844B2
(en)
|
2006-03-29 |
2008-11-25 |
Merial Limited |
Vaccine against streptococci
|
WO2007121522A1
(en)
|
2006-04-21 |
2007-11-01 |
Minister for Primary Industries For And On Behalf Of The State Of New South Wales |
Pestivirus species
|
WO2008017636A2
(en)
|
2006-08-09 |
2008-02-14 |
Spirogene Pty Ltd |
Genes and proteins of brachyspira hyodysenteriae and uses thereof
|
EP2363407A1
(en)
|
2008-02-28 |
2011-09-07 |
Murdoch University |
Novel sequences of Brachyspira, immunogenic compositions, methods for preparation and use thereof
|
AU2009227986C1
(en)
|
2008-03-27 |
2014-06-19 |
Murdoch University |
Novel sequences of Brachyspira, immunogenic compositions, methods for preparation and use thereof
|
EP2419121B1
(en)
|
2009-04-17 |
2018-07-18 |
New York University |
Peptides targeting tnf family receptors and antagonizing tnf action, compositions, methods and uses thereof
|
US20110076232A1
(en)
|
2009-09-29 |
2011-03-31 |
Ludwig Institute For Cancer Research |
Specific binding proteins and uses thereof
|
WO2011084882A2
(en)
|
2010-01-05 |
2011-07-14 |
Contrafect Corporation |
Methods and compositions for enhanced immunological therapy and targeting of gram-positive bacteria
|
WO2011113118A1
(en)
|
2010-03-19 |
2011-09-22 |
Katholieke Universiteit Leuven |
Drug tolerance/persistence of fungal biofilms
|
EP2808344A1
(en)
|
2010-06-01 |
2014-12-03 |
Monash University |
Antibodies directed to the receptor tyrosine kinase c-Met
|
WO2012064286A1
(en)
|
2010-11-11 |
2012-05-18 |
Agency For Science, Technology And Research |
Targeting metabolic enzymes in human cancer
|
GB201107467D0
(en)
|
2011-05-05 |
2011-06-15 |
Univ Leuven Kath |
Novel treatment of pain
|
EP3210627B1
(en)
|
2012-07-12 |
2022-12-21 |
Hangzhou Dac Biotech Co., Ltd |
Conjugates of cell binding molecules with cytotoxic agents
|
CA2891280C
(en)
|
2012-11-24 |
2018-03-20 |
Hangzhou Dac Biotech Co., Ltd. |
Hydrophilic linkers and their uses for conjugation of drugs to cell binding molecules
|
EP3013857B1
(en)
|
2013-06-28 |
2021-06-23 |
Singapore Health Services Pte Ltd |
Trpm4 channel inhibitors for stroke treatment
|
JP6332773B2
(ja)
|
2013-09-02 |
2018-05-30 |
ハンジョウ ディーエーシー バイオテック シーオー.,エルティディ.Hangzhou Dac Biotech Co.,Ltd. |
薬物と細胞結合分子との共役のための新規細胞毒性分子
|
EP3122757B1
(en)
|
2014-02-28 |
2023-09-06 |
Hangzhou Dac Biotech Co., Ltd |
Charged linkers and their uses for conjugation
|
CN113350518A
(zh)
|
2015-07-12 |
2021-09-07 |
杭州多禧生物科技有限公司 |
与细胞结合分子的共轭偶联的桥连接体
|
US9839687B2
(en)
|
2015-07-15 |
2017-12-12 |
Suzhou M-Conj Biotech Co., Ltd. |
Acetylenedicarboxyl linkers and their uses in specific conjugation of a cell-binding molecule
|
JP7138350B2
(ja)
|
2016-11-14 |
2022-09-16 |
ハンジョウ ディーエーシー バイオテック シーオー.,エルティディ. |
共役連結体、該連結体を含有する細胞結合分子-薬物共役体、並びに該共役体及び連結体の使用及び製造方法
|
US20230025327A1
(en)
|
2019-06-29 |
2023-01-26 |
Hangzhou Dac Biotech Co., Ltd. |
Conjugates of tubulysin derivatives and cell binding molecules and methods of making
|
CA3108168A1
(en)
|
2020-02-05 |
2021-08-05 |
Yue Zhang |
Conjugates of cell-binding molecules with cytotoxic agents
|
EP4100435A1
(en)
|
2020-02-05 |
2022-12-14 |
Larimar Therapeutics, Inc. |
Tat peptide binding proteins and uses thereof
|