ES514224A0 - "procedimiento para la preparacion de 2,4-diamino-(3,5-dimetoxi-4-metoxietoxibenzil)-pirimidina". - Google Patents

"procedimiento para la preparacion de 2,4-diamino-(3,5-dimetoxi-4-metoxietoxibenzil)-pirimidina".

Info

Publication number
ES514224A0
ES514224A0 ES514224A ES514224A ES514224A0 ES 514224 A0 ES514224 A0 ES 514224A0 ES 514224 A ES514224 A ES 514224A ES 514224 A ES514224 A ES 514224A ES 514224 A0 ES514224 A0 ES 514224A0
Authority
ES
Spain
Prior art keywords
metoxietoxibenzil
pirimidina
dimetoxi
diamino
procedure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES514224A
Other languages
English (en)
Other versions
ES8304950A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Proter SpA
Original Assignee
Proter SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=11207307&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES514224(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Proter SpA filed Critical Proter SpA
Publication of ES8304950A1 publication Critical patent/ES8304950A1/es
Publication of ES514224A0 publication Critical patent/ES514224A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48—Two nitrogen atoms
    • C07D239/49—Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim
ES514224A 1981-08-11 1982-07-22 "procedimiento para la preparacion de 2,4-diamino-(3,5-dimetoxi-4-metoxietoxibenzil)-pirimidina". Granted ES514224A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT23462/81A IT1138146B (it) 1981-08-11 1981-08-11 Processo per la produzione della 2,4-diammino-(3,5-dimetossi-4-metos sietossi-benzil)-pirimidina

Publications (2)

Publication Number Publication Date
ES8304950A1 ES8304950A1 (es) 1983-04-01
ES514224A0 true ES514224A0 (es) 1983-04-01

Family

ID=11207307

Family Applications (1)

Application Number Title Priority Date Filing Date
ES514224A Granted ES514224A0 (es) 1981-08-11 1982-07-22 "procedimiento para la preparacion de 2,4-diamino-(3,5-dimetoxi-4-metoxietoxibenzil)-pirimidina".

Country Status (10)

Country Link
US (1) US4485248A (es)
EP (1) EP0071741B1 (es)
AR (1) AR230272A1 (es)
AT (1) ATE16800T1 (es)
CA (1) CA1182819A (es)
DE (1) DE3267778D1 (es)
ES (1) ES514224A0 (es)
IT (1) IT1138146B (es)
MX (1) MX156026A (es)
YU (1) YU161382A (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2343282B1 (en) 2004-03-05 2015-07-22 F. Hoffmann-La Roche AG Diaminopyrimidines as P2X3 and P2X2/3 antagonists
ES2562056T3 (es) * 2005-09-01 2016-03-02 F. Hoffmann-La Roche Ag Diaminopirimidinas como moduladores P2X3 y P2X2/3
EP1924565B1 (en) * 2005-09-01 2016-09-14 F.Hoffmann-La Roche Ag Diaminopyrimidines as p2x3 and p3x2/3 modulators
WO2007025899A1 (en) * 2005-09-01 2007-03-08 F. Hoffmann-La Roche Ag Diaminopyrimidines as p2x3 and p2x2/3 modulators

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3485840A (en) * 1964-11-12 1969-12-23 Hoffmann La Roche 2,4-diamino - 5 - (2',4',5'-substituted benzyl) pyrimidines,intermediates and processes
DE2165362A1 (de) * 1970-12-29 1972-07-27 Nisshin Flour Milling Co. Ltd., Tokio .-Verfahren zur Herstellung von Pyrimidinderivaten
BE789904A (fr) * 1971-10-12 1973-04-10 Wellcome Found Procedes de synthese organique
YU34880B (en) * 1972-05-08 1980-04-30 Pliva Pharm & Chem Works Process for preparing 2,4-diamino-5-(3,4,5-trimethoxybenzyl)-pyrimidine
US4143227A (en) * 1973-02-26 1979-03-06 Hoffmann-La Roche Inc. Process for substituted 5-benzyl-2,4-diamino-pyrimidines
US4255574A (en) * 1973-02-26 1981-03-10 Hoffmann-La Roche Inc. Process for preparing 2,4-diamino-pyrimidines
CA1084498A (en) * 1977-05-05 1980-08-26 Alexander E. Wick Benzylpyrimidines and process for the preparation thereof
GR71725B (es) * 1977-11-10 1983-06-22 Hoffmann La Roche
US4258045A (en) * 1979-11-30 1981-03-24 Merck & Co., Inc. Inhibitor of dihydrofolate reductase

Also Published As

Publication number Publication date
AR230272A1 (es) 1984-03-01
ES8304950A1 (es) 1983-04-01
CA1182819A (en) 1985-02-19
EP0071741A1 (en) 1983-02-16
IT1138146B (it) 1986-09-17
MX156026A (es) 1988-06-16
YU161382A (en) 1985-03-20
US4485248A (en) 1984-11-27
ATE16800T1 (de) 1985-12-15
DE3267778D1 (en) 1986-01-16
IT8123462A0 (it) 1981-08-11
EP0071741B1 (en) 1985-12-04

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19991102