MX156026A - Procedimiento para la produccion de la 2,4-diamino-(3,5-dimetoxi 4-metoxietoxi benzil) pirimidina - Google Patents

Procedimiento para la produccion de la 2,4-diamino-(3,5-dimetoxi 4-metoxietoxi benzil) pirimidina

Info

Publication number
MX156026A
MX156026A MX193971A MX19397182A MX156026A MX 156026 A MX156026 A MX 156026A MX 193971 A MX193971 A MX 193971A MX 19397182 A MX19397182 A MX 19397182A MX 156026 A MX156026 A MX 156026A
Authority
MX
Mexico
Prior art keywords
metoxietoxi
pirimidina
dimetoxi
benzil
diamino
Prior art date
Application number
MX193971A
Other languages
English (en)
Inventor
Leone Dall Asta
Original Assignee
Proter Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=11207307&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX156026(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Proter Spa filed Critical Proter Spa
Publication of MX156026A publication Critical patent/MX156026A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48Two nitrogen atoms
    • C07D239/49Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
MX193971A 1981-08-11 1982-08-10 Procedimiento para la produccion de la 2,4-diamino-(3,5-dimetoxi 4-metoxietoxi benzil) pirimidina MX156026A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT23462/81A IT1138146B (it) 1981-08-11 1981-08-11 Processo per la produzione della 2,4-diammino-(3,5-dimetossi-4-metos sietossi-benzil)-pirimidina

Publications (1)

Publication Number Publication Date
MX156026A true MX156026A (es) 1988-06-16

Family

ID=11207307

Family Applications (1)

Application Number Title Priority Date Filing Date
MX193971A MX156026A (es) 1981-08-11 1982-08-10 Procedimiento para la produccion de la 2,4-diamino-(3,5-dimetoxi 4-metoxietoxi benzil) pirimidina

Country Status (10)

Country Link
US (1) US4485248A (es)
EP (1) EP0071741B1 (es)
AR (1) AR230272A1 (es)
AT (1) ATE16800T1 (es)
CA (1) CA1182819A (es)
DE (1) DE3267778D1 (es)
ES (1) ES514224A0 (es)
IT (1) IT1138146B (es)
MX (1) MX156026A (es)
YU (1) YU161382A (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100822530B1 (ko) 2004-03-05 2008-04-16 에프. 호프만-라 로슈 아게 P2x3 및 p2x2/3 길항물질로서의 다이아미노피리미딘
JP4850913B2 (ja) * 2005-09-01 2012-01-11 エフ.ホフマン−ラ ロシュ アーゲー P2x3及びp2x2/3調節因子としてのジアミノピリジン
CN101253159B (zh) * 2005-09-01 2011-12-07 弗·哈夫曼-拉罗切有限公司 作为p2x3和p2x2/3调节剂的二氨基嘧啶类化合物
EP1924564B1 (en) * 2005-09-01 2016-11-09 F.Hoffmann-La Roche Ag Diaminopyrimidines as p2x3 and p2x2/3 modulators

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3485840A (en) * 1964-11-12 1969-12-23 Hoffmann La Roche 2,4-diamino - 5 - (2',4',5'-substituted benzyl) pyrimidines,intermediates and processes
DE2165362A1 (de) * 1970-12-29 1972-07-27 Nisshin Flour Milling Co. Ltd., Tokio .-Verfahren zur Herstellung von Pyrimidinderivaten
BE789904A (fr) * 1971-10-12 1973-04-10 Wellcome Found Procedes de synthese organique
YU34880B (en) * 1972-05-08 1980-04-30 Pliva Pharm & Chem Works Process for preparing 2,4-diamino-5-(3,4,5-trimethoxybenzyl)-pyrimidine
US4143227A (en) * 1973-02-26 1979-03-06 Hoffmann-La Roche Inc. Process for substituted 5-benzyl-2,4-diamino-pyrimidines
US4255574A (en) * 1973-02-26 1981-03-10 Hoffmann-La Roche Inc. Process for preparing 2,4-diamino-pyrimidines
CA1084498A (en) * 1977-05-05 1980-08-26 Alexander E. Wick Benzylpyrimidines and process for the preparation thereof
GR71725B (es) * 1977-11-10 1983-06-22 Hoffmann La Roche
US4258045A (en) * 1979-11-30 1981-03-24 Merck & Co., Inc. Inhibitor of dihydrofolate reductase

Also Published As

Publication number Publication date
AR230272A1 (es) 1984-03-01
EP0071741B1 (en) 1985-12-04
IT8123462A0 (it) 1981-08-11
YU161382A (en) 1985-03-20
US4485248A (en) 1984-11-27
EP0071741A1 (en) 1983-02-16
DE3267778D1 (en) 1986-01-16
ES8304950A1 (es) 1983-04-01
ES514224A0 (es) 1983-04-01
ATE16800T1 (de) 1985-12-15
IT1138146B (it) 1986-09-17
CA1182819A (en) 1985-02-19

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