ES513388A0 - Procedimiento de obtencion de agentes de beta bloqueantes conteniendo grupos de ester con propiedades oftalmologicas. - Google Patents
Procedimiento de obtencion de agentes de beta bloqueantes conteniendo grupos de ester con propiedades oftalmologicas.Info
- Publication number
- ES513388A0 ES513388A0 ES513388A ES513388A ES513388A0 ES 513388 A0 ES513388 A0 ES 513388A0 ES 513388 A ES513388 A ES 513388A ES 513388 A ES513388 A ES 513388A ES 513388 A0 ES513388 A0 ES 513388A0
- Authority
- ES
- Spain
- Prior art keywords
- ophthalmological
- ester
- procedure
- properties
- containing groups
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/276,465 US4455317A (en) | 1981-06-23 | 1981-06-23 | Method for treating glaucoma by the topical administration of selectively metabolized beta-blocking agents |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8405358A1 ES8405358A1 (es) | 1984-06-01 |
ES513388A0 true ES513388A0 (es) | 1984-06-01 |
Family
ID=23056760
Family Applications (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES513388A Granted ES513388A0 (es) | 1981-06-23 | 1982-06-23 | Procedimiento de obtencion de agentes de beta bloqueantes conteniendo grupos de ester con propiedades oftalmologicas. |
ES530207A Granted ES530207A0 (es) | 1981-06-23 | 1984-03-01 | Procedimiento de obtencion de agentes beta-bloqueantes conteniendo grupos ester con propiedades oftalmologicas |
ES530209A Expired ES8507469A1 (es) | 1981-06-23 | 1984-03-01 | Procedimiento de obtencion de agentes de beta-bloqueantes conteniendo grupos ester con propiedades oftalmologicas |
ES530208A Expired ES8507468A1 (es) | 1981-06-23 | 1984-03-01 | Procedimiento de obtencion de agentes de beta-bloqueantes conteniendo grupos ester con propiedades oftalmologicas |
Family Applications After (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES530207A Granted ES530207A0 (es) | 1981-06-23 | 1984-03-01 | Procedimiento de obtencion de agentes beta-bloqueantes conteniendo grupos ester con propiedades oftalmologicas |
ES530209A Expired ES8507469A1 (es) | 1981-06-23 | 1984-03-01 | Procedimiento de obtencion de agentes de beta-bloqueantes conteniendo grupos ester con propiedades oftalmologicas |
ES530208A Expired ES8507468A1 (es) | 1981-06-23 | 1984-03-01 | Procedimiento de obtencion de agentes de beta-bloqueantes conteniendo grupos ester con propiedades oftalmologicas |
Country Status (18)
Country | Link |
---|---|
US (1) | US4455317A (es) |
EP (1) | EP0081581B1 (es) |
JP (1) | JPS58500995A (es) |
AU (1) | AU558475B2 (es) |
CA (1) | CA1176987A (es) |
CH (1) | CH655443B (es) |
DE (1) | DE3248837T1 (es) |
EG (1) | EG16713A (es) |
ES (4) | ES513388A0 (es) |
GB (1) | GB2112786B (es) |
GR (1) | GR76842B (es) |
IL (1) | IL66071A (es) |
IT (1) | IT1156373B (es) |
NL (1) | NL8220253A (es) |
NZ (1) | NZ200973A (es) |
PH (1) | PH18764A (es) |
WO (1) | WO1983000015A1 (es) |
ZA (1) | ZA824341B (es) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4609663A (en) * | 1984-09-11 | 1986-09-02 | Alcon Laboratories, Inc. | Aldose reductase inhibitors useful in glaucoma therapy |
CA1334168C (en) * | 1988-04-26 | 1995-01-31 | Louis M. De Santis | Antiglaucoma compositions containing combinations of .alpha.-2 agonists and .beta. blockers |
US4897417A (en) * | 1988-12-15 | 1990-01-30 | E. I. Du Pont De Nemours & Co. | Prodrugs of 3,4-hydroxy benzoyloxypropanolamines |
US4966914A (en) * | 1988-12-15 | 1990-10-30 | E. I. Du Pont De Nemours And Company | Oculoselective beta-blockers as antiglaucoma agents |
US5536749A (en) * | 1994-10-13 | 1996-07-16 | Sl Pharmaceuticals, Inc. | Method for attenuation of sympathetic nervous system activity or onset of migraine by selectively metabolized beta-blocking agents |
JP4241926B2 (ja) | 1995-10-10 | 2009-03-18 | ウィリアム ジョン ルイス | 3―アミノ―プロポキシフェニル誘導体(1) |
US6197817B1 (en) | 1999-01-22 | 2001-03-06 | Selectus Pharmaceuticals, Inc. | Phenylpropionic acids and esters: compounds and methods for inducing beta-blockade for the treatment of cardiac disorders |
WO2005115375A1 (en) * | 2004-05-25 | 2005-12-08 | Othera Pharmaceuticals, Inc. | Oculoselective drugs and prodrugs |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3868460A (en) * | 1967-02-06 | 1975-02-25 | Boehringer Sohn Ingelheim | Therapeutic compositions and method |
US3740444A (en) * | 1968-01-25 | 1973-06-19 | Boehringer Sohn Ingelheim | Therapeutic compositions and method |
GB1285038A (en) * | 1969-02-21 | 1972-08-09 | Ici Ltd | Alkanolamine derivatives |
DE1922003C3 (de) * | 1969-04-30 | 1979-10-11 | Boehringer Mannheim Gmbh, 6800 Mannheim | N-(3-Aryloxy-2-hydroxypropyl)-aminocarbonsäuren, deren Ester, Amide und Salze, Verfahren zur Herstellung dieser Verbindungen und deren Verwendung bei der Bekämpfung von Herzinsuffizienz |
JPS49247A (es) * | 1972-04-17 | 1974-01-05 | ||
US3839584A (en) * | 1972-08-31 | 1974-10-01 | Interx Research Corp | Pharmaceutical compositions containing a novel ester of ((methylamino)methyl)benzyl alcohol and methods of using same |
FR2208653A2 (en) * | 1972-12-06 | 1974-06-28 | Orsymonde | Cardiac antiarrhythmic phloroglucinol ethers - of hydroxy alkylaminoalkanoic acids |
AT330150B (de) * | 1973-02-28 | 1976-06-10 | Boehringer Sohn Ingelheim | Verfahren zur herstellung von neuen 1-phenoxy-2-hydroxy -3- propargylaminopropanen und von deren saureadditionssalzen |
US3825583A (en) * | 1973-04-26 | 1974-07-23 | Interx Research Corp | Ester of 3-hydroxy-alpha-((methylamino)methyl)benzyl alcohol |
US4195085A (en) * | 1975-09-26 | 1980-03-25 | Merck & Co., Inc. | Compositions and methods for treating glaucoma by the topical administration of t-butylamino-3-(4-morpholino-1,2,5-thiadiazol-3-yloxy-2-phopanol hydrogen maleate |
US4146638A (en) * | 1976-02-17 | 1979-03-27 | Boehringer Ingelheim Gmbh | N-(3-phenoxy-2-hydroxy-propyl)-n-(2-phenyl-2-hydroxy-ethyl)-amines |
US4191765A (en) * | 1976-05-25 | 1980-03-04 | Hoechst Aktiengesellschaft | 1-Aryloxy-2-hydroxy-3-aminopropanes |
US4080471A (en) * | 1976-06-25 | 1978-03-21 | Aktiebolaget Hassle | Use of substituted isopropylaminopropanols for inducing inotropic effects of the human heart |
DE2752659A1 (de) * | 1976-12-07 | 1978-06-08 | Sandoz Ag | Neue tetralinderivate, ihre herstellung und verwendung |
US4127674A (en) * | 1977-03-21 | 1978-11-28 | Allergan Pharmaceuticals, Inc. | Method of treatment for glaucoma |
EP0003664B1 (en) * | 1978-02-08 | 1982-02-17 | Imperial Chemical Industries Plc | Alkanolamine derivatives, process for their preparation and pharmaceutical compositions containing them |
SE8004087L (sv) * | 1980-06-02 | 1981-12-03 | Haessle Ab | Nya parasubstituerade 3-fenoxi-1-alkylaminopropanol-2-er med betareceptorblockerande egenskaper, samt forfarande for deras framstellning, farmaceutiska beredningar innehallande desamma, och metod att behandla akut ... |
SE8004088L (sv) * | 1980-06-02 | 1981-12-03 | Haessle Ab | Nya substituerade 3-fenoxi-l-alkoxikarbonylalkylamino-propanol-2-er med beta-receptorblockerande egenskaper samt forfarande for deras framstellning, farmaceutiska beredningar innehallande desamma och metod att ... |
EP0053434B1 (en) * | 1980-11-28 | 1986-08-27 | American Hospital Supply Corporation | Compounds and method for treatment or prophylaxis of cardiac disorders |
-
1981
- 1981-06-23 US US06/276,465 patent/US4455317A/en not_active Expired - Fee Related
-
1982
- 1982-06-14 PH PH27418A patent/PH18764A/en unknown
- 1982-06-14 CA CA000405126A patent/CA1176987A/en not_active Expired
- 1982-06-15 NZ NZ200973A patent/NZ200973A/en unknown
- 1982-06-16 IL IL66071A patent/IL66071A/xx unknown
- 1982-06-18 ZA ZA824341A patent/ZA824341B/xx unknown
- 1982-06-18 GR GR68483A patent/GR76842B/el unknown
- 1982-06-22 IT IT67794/82A patent/IT1156373B/it active
- 1982-06-23 GB GB08303062A patent/GB2112786B/en not_active Expired
- 1982-06-23 WO PCT/US1982/000850 patent/WO1983000015A1/en active IP Right Grant
- 1982-06-23 NL NL8220253A patent/NL8220253A/nl not_active Application Discontinuation
- 1982-06-23 EP EP82902334A patent/EP0081581B1/en not_active Expired
- 1982-06-23 CH CH110383A patent/CH655443B/de unknown
- 1982-06-23 EG EG369/82A patent/EG16713A/xx active
- 1982-06-23 ES ES513388A patent/ES513388A0/es active Granted
- 1982-06-23 JP JP57502281A patent/JPS58500995A/ja active Pending
- 1982-06-23 DE DE823248837T patent/DE3248837T1/de not_active Withdrawn
- 1982-06-23 AU AU87370/82A patent/AU558475B2/en not_active Ceased
-
1984
- 1984-03-01 ES ES530207A patent/ES530207A0/es active Granted
- 1984-03-01 ES ES530209A patent/ES8507469A1/es not_active Expired
- 1984-03-01 ES ES530208A patent/ES8507468A1/es not_active Expired
Also Published As
Publication number | Publication date |
---|---|
NZ200973A (en) | 1986-04-11 |
GB8303062D0 (en) | 1983-03-09 |
EP0081581A1 (en) | 1983-06-22 |
IL66071A (en) | 1986-09-30 |
GB2112786B (en) | 1986-02-19 |
EG16713A (en) | 1990-10-30 |
IT1156373B (it) | 1987-02-04 |
WO1983000015A1 (en) | 1983-01-06 |
AU8737082A (en) | 1983-01-18 |
CH655443B (es) | 1986-04-30 |
ES8405358A1 (es) | 1984-06-01 |
DE3248837T1 (de) | 1983-12-01 |
ES8507467A1 (es) | 1985-09-01 |
GR76842B (es) | 1984-09-04 |
AU558475B2 (en) | 1987-01-29 |
ZA824341B (en) | 1983-04-27 |
NL8220253A (nl) | 1983-05-02 |
ES530207A0 (es) | 1985-09-01 |
PH18764A (en) | 1985-09-20 |
ES530209A0 (es) | 1985-09-01 |
ES8507469A1 (es) | 1985-09-01 |
EP0081581B1 (en) | 1986-12-30 |
ES530208A0 (es) | 1985-09-01 |
ES8507468A1 (es) | 1985-09-01 |
IT8267794A0 (it) | 1982-06-22 |
CA1176987A (en) | 1984-10-30 |
IL66071A0 (en) | 1982-09-30 |
US4455317A (en) | 1984-06-19 |
GB2112786A (en) | 1983-07-27 |
EP0081581A4 (en) | 1983-11-21 |
JPS58500995A (ja) | 1983-06-23 |
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