ES509535A0 - "un metodo de preparar una 4-ariloxi-1,2,3,4-tetrahidroisoquinoleina". - Google Patents

"un metodo de preparar una 4-ariloxi-1,2,3,4-tetrahidroisoquinoleina".

Info

Publication number
ES509535A0
ES509535A0 ES509535A ES509535A ES509535A0 ES 509535 A0 ES509535 A0 ES 509535A0 ES 509535 A ES509535 A ES 509535A ES 509535 A ES509535 A ES 509535A ES 509535 A0 ES509535 A0 ES 509535A0
Authority
ES
Spain
Prior art keywords
sub
alkyl
hydrogen
aryloxy
tetrahydroisokinolein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES509535A
Other languages
English (en)
Other versions
ES8305336A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharmaceuticals Inc
Original Assignee
Hoechst Roussel Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharmaceuticals Inc filed Critical Hoechst Roussel Pharmaceuticals Inc
Publication of ES8305336A1 publication Critical patent/ES8305336A1/es
Publication of ES509535A0 publication Critical patent/ES509535A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/24—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ES509535A 1981-02-19 1982-02-12 "un metodo de preparar una 4-ariloxi-1,2,3,4-tetrahidroisoquinoleina". Granted ES509535A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/235,801 US4375471A (en) 1981-02-19 1981-02-19 4-Aryloxy-1,2,3,4-tetrahydroisoquinolines

Publications (2)

Publication Number Publication Date
ES8305336A1 ES8305336A1 (es) 1983-04-01
ES509535A0 true ES509535A0 (es) 1983-04-01

Family

ID=22886966

Family Applications (1)

Application Number Title Priority Date Filing Date
ES509535A Granted ES509535A0 (es) 1981-02-19 1982-02-12 "un metodo de preparar una 4-ariloxi-1,2,3,4-tetrahidroisoquinoleina".

Country Status (7)

Country Link
US (1) US4375471A (es)
EP (1) EP0058932B1 (es)
JP (1) JPS57163368A (es)
AT (1) ATE14308T1 (es)
CA (1) CA1173833A (es)
DE (1) DE3264708D1 (es)
ES (1) ES509535A0 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2564461B1 (fr) * 1984-05-15 1986-09-19 Synthelabo Derives d'isoquinoleine, leur preparation et leurs applications
DE3640641A1 (de) * 1986-11-28 1988-07-14 Thomae Gmbh Dr K Neue heteroaromatische aminderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
ES2116601T3 (es) * 1993-06-22 1998-07-16 Knoll Ag Derivados de isoquinolina como agentes terapeuticos.
CA2424292A1 (en) 2000-10-10 2002-04-18 Calyx Therapeutics, Inc. Tricyclic compounds and uses thereof
WO2004050629A2 (en) * 2002-12-02 2004-06-17 Pharmacia & Upjohn Company Llc The use of 4-phenyl substituted tetrahydroisoquinolines in the treatment of pain, migraine and urinary incontinence
CA2505783A1 (en) * 2002-12-02 2004-06-17 Pharmacia & Upjohn Company Llc The use of 4-phenyl-substituted tetrahydroisoquinolines in the treatment of pain, migraine headaches and urinary incontinence
AU2003283646A1 (en) * 2002-12-02 2004-06-23 Pharmacia & Upjohn Company Llc The use of aryl- and heteroaryl-substituted tetrahydroisoquinolines in the treatment of chronic and neuropathic pain, migraine headaches, and urge, stress and mixed urinary incontinence

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1035777A (en) * 1963-08-20 1966-07-13 Bellon Labor Sa Roger Isoquinoline derivatives
NL6504208A (es) * 1964-04-03 1965-10-04
DE1670694B2 (de) * 1966-05-05 1976-07-22 Hoechst Ag, 6000 Frankfurt Verfahren zur herstellung von tetrahydroisochinolinen
US3629265A (en) * 1969-10-30 1971-12-21 Hoffmann La Roche 7-halo-4-isoquinolones
US4059586A (en) * 1974-03-28 1977-11-22 Marion Laboratories, Inc. 5-Alkoxy-2-alkyl-1,2,3,4-tetrahydroisoquinolene-8-carboxaldehyde and derivatives
GB1504424A (en) * 1975-08-09 1978-03-22 Beecham Group Ltd Isoquinoline-derived aminoethers
JPS54138572A (en) * 1978-04-17 1979-10-27 Kyowa Hakko Kogyo Co Ltd Novel isoquinoline derivative

Also Published As

Publication number Publication date
EP0058932A3 (en) 1982-10-27
ES8305336A1 (es) 1983-04-01
US4375471A (en) 1983-03-01
CA1173833A (en) 1984-09-04
EP0058932B1 (en) 1985-07-17
ATE14308T1 (de) 1985-08-15
EP0058932A2 (en) 1982-09-01
DE3264708D1 (en) 1985-08-22
JPS57163368A (en) 1982-10-07

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