ES494634A0 - Procedimiento para la preparacion de compuestos de cefem y cefam - Google Patents
Procedimiento para la preparacion de compuestos de cefem y cefamInfo
- Publication number
- ES494634A0 ES494634A0 ES494634A ES494634A ES494634A0 ES 494634 A0 ES494634 A0 ES 494634A0 ES 494634 A ES494634 A ES 494634A ES 494634 A ES494634 A ES 494634A ES 494634 A0 ES494634 A0 ES 494634A0
- Authority
- ES
- Spain
- Prior art keywords
- cefam
- cefem
- compounds
- procedure
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
- C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C17/00—Preparation of halogenated hydrocarbons
- C07C17/26—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton
- C07C17/263—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton by condensation reactions
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D249/12—Oxygen or sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
- C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D257/04—Five-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/01—Five-membered rings
- C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
- C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
- C07D285/08—1,2,4-Thiadiazoles; Hydrogenated 1,2,4-thiadiazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
- C07D295/21—Radicals derived from sulfur analogues of carbonic acid
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cephalosporin Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB7850334 | 1978-12-29 | ||
GB7935538 | 1979-10-12 | ||
AU23283/84A AU2328384A (en) | 1978-12-29 | 1984-01-13 | 1,2,4-thiadiazole derivatives |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8107231A1 ES8107231A1 (es) | 1981-08-16 |
ES494634A0 true ES494634A0 (es) | 1981-08-16 |
Family
ID=32965859
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES487358A Granted ES487358A0 (es) | 1978-12-29 | 1979-12-28 | Un procedimiento para la preparacion de compuestos de cefem y cefam |
ES494635A Expired ES8107207A1 (es) | 1978-12-29 | 1980-08-29 | Procedimiento de preparacion de derivados de tiadiazol |
ES494634A Granted ES494634A0 (es) | 1978-12-29 | 1980-08-29 | Procedimiento para la preparacion de compuestos de cefem y cefam |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES487358A Granted ES487358A0 (es) | 1978-12-29 | 1979-12-28 | Un procedimiento para la preparacion de compuestos de cefem y cefam |
ES494635A Expired ES8107207A1 (es) | 1978-12-29 | 1980-08-29 | Procedimiento de preparacion de derivados de tiadiazol |
Country Status (8)
Country | Link |
---|---|
US (1) | US4331665A (es) |
EP (2) | EP0013762B1 (es) |
JP (1) | JPH02223572A (es) |
AU (2) | AU536842B2 (es) |
DE (1) | DE2967410D1 (es) |
DK (1) | DK554279A (es) |
ES (3) | ES487358A0 (es) |
MX (1) | MX5973E (es) |
Families Citing this family (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1592149A (en) * | 1976-10-08 | 1981-07-01 | Fujisawa Pharmaceutical Co | 3 7-disubstituted-3-cephem-4-carboxylic acid compounds and processes for preparation thereof |
US4390534A (en) * | 1978-12-29 | 1983-06-28 | Fujisawa Pharmaceutical Co., Ltd. | Cephem and cepham compounds |
FI802107A (fi) * | 1979-07-05 | 1981-01-06 | Ciba Geigy Ag | Aminotiadiazolylfoereningar foerfarande foer deras framstaellning farmaceutiska preparat som innehaoller saodana foereningar och anvaendning av de sistnaemda |
EP0025017A1 (de) * | 1979-08-28 | 1981-03-11 | Ciba-Geigy Ag | Polyazathiaverbindungen, Verfahren zu ihrer Herstellung, pharmazeutische Präparate enthaltend solche Verbindungen und Verwendung von letzteren |
GR75644B (es) * | 1980-06-18 | 1984-08-02 | Fujisawa Pharmaceutical Co | |
GR78245B (es) * | 1980-09-12 | 1984-09-26 | Ciba Geigy Ag | |
US4338452A (en) * | 1980-09-17 | 1982-07-06 | Eli Lilly And Company | 1-and 2-(1-Alkyl-1H-tetrazol-5-yl-methyl)-1H-tetrazol-5-thiols and 1-cyanomethyl tetrazole-5-thiol |
US4431642A (en) * | 1980-12-01 | 1984-02-14 | Fujisawa Pharmaceutical Co., Ltd. | Cephem compounds |
US4521413A (en) * | 1981-09-14 | 1985-06-04 | Fujisawa Pharmaceutical Co., Ltd. | Cephem compounds |
US4563449A (en) * | 1982-07-19 | 1986-01-07 | Fujisawa Pharmaceutical Co., Ltd. | Cephem compounds |
DE3247613A1 (de) * | 1982-12-23 | 1984-07-05 | Hoechst Ag, 6230 Frankfurt | Cephalosporinderivate und verfahren zu ihrer herstellung |
DE3300593A1 (de) * | 1983-01-11 | 1984-07-12 | Bayer Ag, 5090 Leverkusen | Neue cephalosporine und verfahren zu ihrer herstellung |
US4529490A (en) * | 1983-05-23 | 1985-07-16 | General Electric Company | Photopolymerizable organic compositions and diaryliodonium ketone salts used therein |
US4690921A (en) * | 1983-10-11 | 1987-09-01 | Yamanouchi Pharmaceutical Co., Ltd. | Cephalosporin compounds and salts thereof |
EP0150609A3 (en) * | 1983-12-30 | 1986-04-23 | Glaxo Group Limited | Cephalosporin antibiotics |
IE61679B1 (en) * | 1987-08-10 | 1994-11-16 | Fujisawa Pharmaceutical Co | Water-soluble antibiotic composition and water-soluble salts of new cephem compounds |
GB9104238D0 (en) * | 1990-03-16 | 1991-04-17 | Ici Pharma | 3-tetrazolylthiomethyl cephalosporin antibiotics |
JPH11101520A (ja) | 1997-09-29 | 1999-04-13 | Sharp Corp | エアサイクル式空気調和装置 |
US7186855B2 (en) | 2001-06-11 | 2007-03-06 | Xenoport, Inc. | Prodrugs of GABA analogs, compositions and uses thereof |
US8048917B2 (en) | 2005-04-06 | 2011-11-01 | Xenoport, Inc. | Prodrugs of GABA analogs, compositions and uses thereof |
WO2009073620A2 (en) * | 2007-11-30 | 2009-06-11 | Newlink Genetics | Ido inhibitors |
EP3616695A1 (en) | 2011-09-09 | 2020-03-04 | Merck Sharp & Dohme Corp. | Methods for treating intrapulmonary infections |
US8809314B1 (en) | 2012-09-07 | 2014-08-19 | Cubist Pharmacueticals, Inc. | Cephalosporin compound |
US8476425B1 (en) | 2012-09-27 | 2013-07-02 | Cubist Pharmaceuticals, Inc. | Tazobactam arginine compositions |
US20140274996A1 (en) | 2013-03-15 | 2014-09-18 | Cubist Pharmaceuticals, Inc. | Tazobactam and ceftolozane antibiotic compositions |
US9872906B2 (en) | 2013-03-15 | 2018-01-23 | Merck Sharp & Dohme Corp. | Ceftolozane antibiotic compositions |
US20140274989A1 (en) | 2013-03-15 | 2014-09-18 | Cubist Pharmaceuticals, Inc. | Manufacturing beta-lactam combination products |
ES2800603T3 (es) | 2013-09-09 | 2021-01-04 | Merck Sharp & Dohme | Tratamiento de infecciones con ceftolozano/tazobactam en sujetos con insuficiencia renal |
US8906898B1 (en) | 2013-09-27 | 2014-12-09 | Calixa Therapeutics, Inc. | Solid forms of ceftolozane |
JP2015174837A (ja) * | 2014-03-14 | 2015-10-05 | 国立大学法人 千葉大学 | ベンゾフラン誘導体の製造方法 |
EP3202763B1 (en) * | 2014-10-02 | 2017-12-13 | Fujifilm Corporation | Method for producing 5-amino-3 substituted-1,2,4-thiadiazole |
US10059680B2 (en) | 2014-12-18 | 2018-08-28 | Merck Sharp & Dohme Corp. | Thiadiazolyl-oximinoacetic acid derivative compounds |
US10214543B2 (en) | 2014-12-30 | 2019-02-26 | Merck Sharp & Dohme Corp. | Synthesis of cephalosporin compounds |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4093803A (en) * | 1971-05-14 | 1978-06-06 | Glaxo Laboratories Limited | 7β-[2-Etherified oximino-2-(thienyl-, furyl- or pyridylacetamido)] cephalosporins |
DK154939C (da) * | 1974-12-19 | 1989-06-12 | Takeda Chemical Industries Ltd | Analogifremgangsmaade til fremstilling af thiazolylacetamido-cephemforbindelser eller farmaceutisk acceptable salte eller estere deraf |
GB1592149A (en) | 1976-10-08 | 1981-07-01 | Fujisawa Pharmaceutical Co | 3 7-disubstituted-3-cephem-4-carboxylic acid compounds and processes for preparation thereof |
PH17188A (en) * | 1977-03-14 | 1984-06-14 | Fujisawa Pharmaceutical Co | New cephem and cepham compounds and their pharmaceutical compositions and method of use |
FR2387235A1 (fr) * | 1978-01-23 | 1978-11-10 | Fujisawa Pharmaceutical Co | Procede de preparation de composes d'acide 3,7-disubstitue-3-cephem-4-carboxylique et nouveaux produits ainsi obtenus, ayant une forte activite antibacterienne |
US4268509A (en) * | 1978-07-10 | 1981-05-19 | Fujisawa Pharmaceutical Co., Ltd. | New cephem compounds and processes for preparation thereof |
-
1979
- 1979-12-20 AU AU54083/79A patent/AU536842B2/en not_active Ceased
- 1979-12-21 DK DK554279A patent/DK554279A/da not_active Application Discontinuation
- 1979-12-28 ES ES487358A patent/ES487358A0/es active Granted
- 1979-12-28 EP EP79105399A patent/EP0013762B1/en not_active Expired
- 1979-12-28 DE DE7979105399T patent/DE2967410D1/de not_active Expired
- 1979-12-28 EP EP82100599A patent/EP0064582B1/en not_active Expired
-
1980
- 1980-01-02 MX MX808564U patent/MX5973E/es unknown
- 1980-03-07 US US06/128,260 patent/US4331665A/en not_active Expired - Lifetime
- 1980-08-29 ES ES494635A patent/ES8107207A1/es not_active Expired
- 1980-08-29 ES ES494634A patent/ES494634A0/es active Granted
-
1984
- 1984-01-13 AU AU23283/84A patent/AU2328384A/en not_active Abandoned
-
1990
- 1990-01-12 JP JP2005450A patent/JPH02223572A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
EP0064582A1 (en) | 1982-11-17 |
ES8107231A1 (es) | 1981-08-16 |
ES8102140A1 (es) | 1980-12-16 |
ES494635A0 (es) | 1981-08-16 |
EP0013762A2 (en) | 1980-08-06 |
AU5408379A (en) | 1980-07-03 |
AU2328384A (en) | 1984-05-10 |
AU536842B2 (en) | 1984-05-24 |
EP0013762B1 (en) | 1985-03-13 |
JPH02223572A (ja) | 1990-09-05 |
ES487358A0 (es) | 1980-12-16 |
EP0064582B1 (en) | 1985-12-11 |
DK554279A (da) | 1980-06-30 |
EP0013762A3 (en) | 1980-10-01 |
DE2967410D1 (en) | 1985-04-18 |
US4331665A (en) | 1982-05-25 |
ES8107207A1 (es) | 1981-08-16 |
MX5973E (es) | 1984-09-11 |
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