ES490645A0 - Un procedimiento para la produccion de un derivado 4-amino- 3-carboxi o ciano-1,2-dihidro-2-oxo-1,8-naftiridina - Google Patents

Un procedimiento para la produccion de un derivado 4-amino- 3-carboxi o ciano-1,2-dihidro-2-oxo-1,8-naftiridina

Info

Publication number
ES490645A0
ES490645A0 ES490645A ES490645A ES490645A0 ES 490645 A0 ES490645 A0 ES 490645A0 ES 490645 A ES490645 A ES 490645A ES 490645 A ES490645 A ES 490645A ES 490645 A0 ES490645 A0 ES 490645A0
Authority
ES
Spain
Prior art keywords
naftiridine
carboxi
cyan
dihydro
oxo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES490645A
Other languages
English (en)
Spanish (es)
Other versions
ES8104286A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth LLC
Original Assignee
American Home Products Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Home Products Corp filed Critical American Home Products Corp
Publication of ES8104286A1 publication Critical patent/ES8104286A1/es
Publication of ES490645A0 publication Critical patent/ES490645A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/80—Acids; Esters in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ES490645A 1979-04-18 1980-04-17 Un procedimiento para la produccion de un derivado 4-amino- 3-carboxi o ciano-1,2-dihidro-2-oxo-1,8-naftiridina Granted ES490645A0 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3125579A 1979-04-18 1979-04-18
US06/125,600 US4324893A (en) 1979-04-18 1980-02-28 4-Amino-3-carboxy or cyano-1,2-dihydro-2-oxo-1,8-naphthyridine derivatives

Publications (2)

Publication Number Publication Date
ES8104286A1 ES8104286A1 (es) 1981-04-16
ES490645A0 true ES490645A0 (es) 1981-04-16

Family

ID=26707004

Family Applications (1)

Application Number Title Priority Date Filing Date
ES490645A Granted ES490645A0 (es) 1979-04-18 1980-04-17 Un procedimiento para la produccion de un derivado 4-amino- 3-carboxi o ciano-1,2-dihidro-2-oxo-1,8-naftiridina

Country Status (22)

Country Link
US (1) US4324893A (cg-RX-API-DMAC7.html)
EP (2) EP0018735B1 (cg-RX-API-DMAC7.html)
JP (1) JPS56500373A (cg-RX-API-DMAC7.html)
KR (1) KR840000076B1 (cg-RX-API-DMAC7.html)
AR (2) AR225437A1 (cg-RX-API-DMAC7.html)
AU (1) AU531348B2 (cg-RX-API-DMAC7.html)
CA (1) CA1115272A (cg-RX-API-DMAC7.html)
DK (1) DK537780A (cg-RX-API-DMAC7.html)
ES (1) ES490645A0 (cg-RX-API-DMAC7.html)
FI (1) FI801229A7 (cg-RX-API-DMAC7.html)
GB (1) GB2053198B (cg-RX-API-DMAC7.html)
GR (1) GR67253B (cg-RX-API-DMAC7.html)
HU (1) HU183125B (cg-RX-API-DMAC7.html)
IE (1) IE49696B1 (cg-RX-API-DMAC7.html)
IL (1) IL59667A (cg-RX-API-DMAC7.html)
IN (1) IN150969B (cg-RX-API-DMAC7.html)
NZ (1) NZ193445A (cg-RX-API-DMAC7.html)
PH (1) PH16524A (cg-RX-API-DMAC7.html)
PT (1) PT71081A (cg-RX-API-DMAC7.html)
SU (1) SU1131469A3 (cg-RX-API-DMAC7.html)
WO (1) WO1980002287A1 (cg-RX-API-DMAC7.html)
YU (1) YU105680A (cg-RX-API-DMAC7.html)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4420615A (en) * 1981-08-24 1983-12-13 Merck & Co., Inc. Substituted pyridopyrimidines as gastric secretion inhibitors
FR2567520B1 (fr) * 1984-07-11 1987-01-02 Carpibem Nouvelles phenyl-naphthyridines, leur procede de preparation, medicaments les contenant, notamment anti-ulceres
NZ218773A (en) * 1986-01-06 1990-05-28 Carpibem 3-methyl-2-oxo-1-(substituted phenyl)-naphthyridines and pharmaceutical compositions
FR2592650B1 (fr) * 1986-01-06 1988-04-29 Carpibem Nouvelles phenyl-naphtyridines fonctionnalisees en position-3, leur procede de preparation, medicaments les contenant, notamment anti-ulceres.
FR2592651B1 (fr) * 1986-01-06 1988-05-13 Carpibem Nouvelles phenyl naphtyridines comportant un substituant methyle en position 3, et les medicaments qui en contiennent.
FR2592652B1 (fr) * 1986-01-06 1988-04-29 Carpibem Nouvelles phenyl-naphtyridines, leur procede de preparation et les medicaments en contenant.
FR2592649B1 (fr) * 1986-01-06 1988-04-29 Carpibem Cyano et amido phenyl-naphtyridines, leur procede de preparation, medicaments les contenant, notamment anti-ulceres.
NZ218774A (en) * 1986-01-06 1990-06-26 Carpibem 3-substituted phenylnaphthyridines and pharmaceutical compositions
US4916131A (en) * 1986-10-15 1990-04-10 Schering Corporation Naphthyridine derivatives and method for treating allergic reactions
EP0267691A3 (en) * 1986-10-15 1989-08-23 Schering Corporation Use of 1-substituted naphthyridine and pyridopyrazine derivatives for the preparation of medicaments with immunosuppressor activity.
US5037826A (en) * 1986-10-15 1991-08-06 Schering Corporation 1-substituted naphthyridine and pyridopyrazine derivatives
DK273689A (da) * 1988-06-06 1989-12-07 Sanofi Sa 4-amino-3-carboxyquinoliner og -naphthyridiner, fremgangsmaade til deres fremstilling og anvendelse deraf i laegemidler
FR2632861B1 (fr) * 1988-06-15 1990-11-09 Sanofi Sa Derives d'amino-4 carboxy-3 quinoleines et naphtyridines, leur procede de preparation et leur application comme medicaments
FR2632639B1 (fr) * 1988-06-09 1990-10-05 Sanofi Sa Derives d'amino-4 carboxy-3 naphtyridines, leur preparation et compositions pharmaceutiques qui les contiennent
FR2637890B1 (fr) * 1988-09-14 1991-02-01 Europ Propulsion Materiau composite a matrice zircone
GB9318931D0 (en) * 1993-09-14 1993-10-27 Boots Co Plc Therapeutic agents
GB9420168D0 (en) * 1994-10-06 1994-11-23 Boots Co Plc Therapeutic agents
AR029185A1 (es) 1999-10-25 2003-06-18 Yamanouchi Pharma Co Ltd Derivado de naftiridina
MY140679A (en) 2001-05-24 2010-01-15 Avanir Pharmaceuticals Inhibitors of macrohage migration inhibitory factor and methods for identifying the same
KR20020092756A (ko) * 2001-06-05 2002-12-12 이종완 젓갈과 그 제조 방법
TW200418829A (en) 2003-02-14 2004-10-01 Avanir Pharmaceutics Inhibitors of macrophage migration inhibitory factor and methods for identifying the same
WO2004091627A2 (en) * 2003-04-07 2004-10-28 Cylene Pharmaceuticals, Inc. Heterocyclic substituted 1,4-dihydro-4-oxo-1,8-naphthpyridine analogs
MXJL06000006A (es) * 2003-08-22 2006-05-04 Avanir Pharmaceuticals Derivados de naftiridina sustituidos como inhibidores del factor inhibidor de la migracion de macrofagos y su uso en el tratamiento de enfermedades en el hombre.
JP2008534502A (ja) 2005-03-24 2008-08-28 アバニール・ファーマシューティカルズ マクロファージ遊走阻止因子の阻害剤としてのチエノピリジノン誘導体
GB0605689D0 (en) * 2006-03-21 2006-05-03 Novartis Ag Organic compounds
CN113956252A (zh) 2017-09-28 2022-01-21 药捷安康(南京)科技股份有限公司 Pde9抑制剂及其用途
EA202190137A1 (ru) 2018-06-27 2021-05-17 Бристол-Маерс Сквибб Компани Нафтиридиноновые соединения для применения в качестве активаторов t-клеток
CN112654621B (zh) 2018-06-27 2024-05-14 百时美施贵宝公司 可作为t细胞活化剂的经取代萘啶酮化合物
AR119821A1 (es) 2019-08-28 2022-01-12 Bristol Myers Squibb Co Compuestos de piridopirimidinonilo sustituidos útiles como activadores de células t
AR120823A1 (es) 2019-12-23 2022-03-23 Bristol Myers Squibb Co Compuestos bicíclicos sustituidos útiles como activadores de células t
KR20220120624A (ko) 2019-12-23 2022-08-30 브리스톨-마이어스 스큅 컴퍼니 T 세포 활성화제로서 유용한 치환된 피페라진 유도체
AU2020415377A1 (en) 2019-12-23 2022-08-18 Bristol-Myers Squibb Company Substituted quinazolinyl compounds useful as T cell activators

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA947301A (en) * 1970-01-28 1974-05-14 Sumitomo Chemical Company Process for the preparation of compound having antibacterial action
CA988522A (en) * 1972-05-05 1976-05-04 Haydn W.R. Williams 1,8-naphthyridine compounds
US3993656A (en) * 1974-11-19 1976-11-23 Merck & Co., Inc. 1,8-Naphthyridine compounds
US4103257A (en) * 1976-05-25 1978-07-25 The United States Of America As Represented By The United States Department Of Energy Azaquinolone dye lasers
US4133885A (en) * 1977-07-18 1979-01-09 Merck & Co., Inc. Substituted naphthyridinones

Also Published As

Publication number Publication date
ES8104286A1 (es) 1981-04-16
AR227427A1 (es) 1982-10-29
AU5751980A (en) 1980-10-23
DK537780A (da) 1980-12-17
US4324893A (en) 1982-04-13
EP0018735B1 (en) 1983-07-27
NZ193445A (en) 1982-09-07
KR840000076B1 (ko) 1984-02-08
EP0018735A1 (en) 1980-11-12
IE800761L (en) 1980-10-18
HU183125B (en) 1984-04-28
SU1131469A3 (ru) 1984-12-23
IL59667A (en) 1983-11-30
EP0060012B1 (en) 1984-08-29
EP0060012A1 (en) 1982-09-15
YU105680A (en) 1983-09-30
AU531348B2 (en) 1983-08-18
JPS56500373A (cg-RX-API-DMAC7.html) 1981-03-26
FI801229A7 (fi) 1981-01-01
CA1115272A (en) 1981-12-29
AR225437A1 (es) 1982-03-31
IE49696B1 (en) 1985-11-27
WO1980002287A1 (en) 1980-10-30
KR830002759A (ko) 1983-05-30
GR67253B (cg-RX-API-DMAC7.html) 1981-06-26
PH16524A (en) 1983-11-10
PT71081A (en) 1980-05-01
GB2053198B (en) 1983-04-07
IN150969B (cg-RX-API-DMAC7.html) 1983-02-05
GB2053198A (en) 1981-02-04

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