AR227427A1 - Procedimiento para la produccion de derivados 4-sustituidos de amino-3-carboxi o ciano-1,2-dihidro-2-oxo-1,8-naftiridina - Google Patents
Procedimiento para la produccion de derivados 4-sustituidos de amino-3-carboxi o ciano-1,2-dihidro-2-oxo-1,8-naftiridinaInfo
- Publication number
- AR227427A1 AR227427A1 AR285719A AR28571981A AR227427A1 AR 227427 A1 AR227427 A1 AR 227427A1 AR 285719 A AR285719 A AR 285719A AR 28571981 A AR28571981 A AR 28571981A AR 227427 A1 AR227427 A1 AR 227427A1
- Authority
- AR
- Argentina
- Prior art keywords
- naphtiridine
- carboxi
- cyan
- dihydro
- oxo
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
- C07D213/80—Acids; Esters in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3125579A | 1979-04-18 | 1979-04-18 | |
| US06/125,600 US4324893A (en) | 1979-04-18 | 1980-02-28 | 4-Amino-3-carboxy or cyano-1,2-dihydro-2-oxo-1,8-naphthyridine derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR227427A1 true AR227427A1 (es) | 1982-10-29 |
Family
ID=26707004
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AR280667A AR225437A1 (es) | 1979-04-18 | 1980-04-14 | Procedimiento para la produccion de derivados de 4-amino-1,2-dihidro-2-oxo-1,8-naftiridian |
| AR285719A AR227427A1 (es) | 1979-04-18 | 1981-06-16 | Procedimiento para la produccion de derivados 4-sustituidos de amino-3-carboxi o ciano-1,2-dihidro-2-oxo-1,8-naftiridina |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AR280667A AR225437A1 (es) | 1979-04-18 | 1980-04-14 | Procedimiento para la produccion de derivados de 4-amino-1,2-dihidro-2-oxo-1,8-naftiridian |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US4324893A (es) |
| EP (2) | EP0018735B1 (es) |
| JP (1) | JPS56500373A (es) |
| KR (1) | KR840000076B1 (es) |
| AR (2) | AR225437A1 (es) |
| AU (1) | AU531348B2 (es) |
| CA (1) | CA1115272A (es) |
| DK (1) | DK537780A (es) |
| ES (1) | ES490645A0 (es) |
| FI (1) | FI801229A (es) |
| GB (1) | GB2053198B (es) |
| GR (1) | GR67253B (es) |
| HU (1) | HU183125B (es) |
| IE (1) | IE49696B1 (es) |
| IL (1) | IL59667A (es) |
| IN (1) | IN150969B (es) |
| NZ (1) | NZ193445A (es) |
| PH (1) | PH16524A (es) |
| PT (1) | PT71081A (es) |
| SU (1) | SU1131469A3 (es) |
| WO (1) | WO1980002287A1 (es) |
| YU (1) | YU105680A (es) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4420615A (en) * | 1981-08-24 | 1983-12-13 | Merck & Co., Inc. | Substituted pyridopyrimidines as gastric secretion inhibitors |
| FR2567520B1 (fr) * | 1984-07-11 | 1987-01-02 | Carpibem | Nouvelles phenyl-naphthyridines, leur procede de preparation, medicaments les contenant, notamment anti-ulceres |
| FR2592651B1 (fr) * | 1986-01-06 | 1988-05-13 | Carpibem | Nouvelles phenyl naphtyridines comportant un substituant methyle en position 3, et les medicaments qui en contiennent. |
| FR2592650B1 (fr) * | 1986-01-06 | 1988-04-29 | Carpibem | Nouvelles phenyl-naphtyridines fonctionnalisees en position-3, leur procede de preparation, medicaments les contenant, notamment anti-ulceres. |
| NZ218774A (en) * | 1986-01-06 | 1990-06-26 | Carpibem | 3-substituted phenylnaphthyridines and pharmaceutical compositions |
| FR2592652B1 (fr) * | 1986-01-06 | 1988-04-29 | Carpibem | Nouvelles phenyl-naphtyridines, leur procede de preparation et les medicaments en contenant. |
| NZ218773A (en) * | 1986-01-06 | 1990-05-28 | Carpibem | 3-methyl-2-oxo-1-(substituted phenyl)-naphthyridines and pharmaceutical compositions |
| FR2592649B1 (fr) * | 1986-01-06 | 1988-04-29 | Carpibem | Cyano et amido phenyl-naphtyridines, leur procede de preparation, medicaments les contenant, notamment anti-ulceres. |
| US5037826A (en) * | 1986-10-15 | 1991-08-06 | Schering Corporation | 1-substituted naphthyridine and pyridopyrazine derivatives |
| US4916131A (en) * | 1986-10-15 | 1990-04-10 | Schering Corporation | Naphthyridine derivatives and method for treating allergic reactions |
| EP0267691A3 (en) * | 1986-10-15 | 1989-08-23 | Schering Corporation | Use of 1-substituted naphthyridine and pyridopyrazine derivatives for the preparation of medicaments with immunosuppressor activity. |
| FR2632861B1 (fr) * | 1988-06-15 | 1990-11-09 | Sanofi Sa | Derives d'amino-4 carboxy-3 quinoleines et naphtyridines, leur procede de preparation et leur application comme medicaments |
| DK273689A (da) * | 1988-06-06 | 1989-12-07 | Sanofi Sa | 4-amino-3-carboxyquinoliner og -naphthyridiner, fremgangsmaade til deres fremstilling og anvendelse deraf i laegemidler |
| FR2632639B1 (fr) * | 1988-06-09 | 1990-10-05 | Sanofi Sa | Derives d'amino-4 carboxy-3 naphtyridines, leur preparation et compositions pharmaceutiques qui les contiennent |
| FR2637890B1 (fr) * | 1988-09-14 | 1991-02-01 | Europ Propulsion | Materiau composite a matrice zircone |
| GB9318931D0 (en) * | 1993-09-14 | 1993-10-27 | Boots Co Plc | Therapeutic agents |
| GB9420168D0 (en) * | 1994-10-06 | 1994-11-23 | Boots Co Plc | Therapeutic agents |
| AR029185A1 (es) | 1999-10-25 | 2003-06-18 | Yamanouchi Pharma Co Ltd | Derivado de naftiridina |
| UY27304A1 (es) | 2001-05-24 | 2002-12-31 | Avanir Pharmaceuticals | Inhibidores del factor inhibidor de la migración de los macrófagos y métodos para su identificación |
| KR20020092756A (ko) * | 2001-06-05 | 2002-12-12 | 이종완 | 젓갈과 그 제조 방법 |
| TW200418829A (en) | 2003-02-14 | 2004-10-01 | Avanir Pharmaceutics | Inhibitors of macrophage migration inhibitory factor and methods for identifying the same |
| WO2004091627A2 (en) * | 2003-04-07 | 2004-10-28 | Cylene Pharmaceuticals, Inc. | Heterocyclic substituted 1,4-dihydro-4-oxo-1,8-naphthpyridine analogs |
| CA2531506A1 (en) * | 2003-08-22 | 2005-03-10 | Avanir Pharmaceuticals | Substituted naphthyridine derivatives as inhibitors of macrophage migration inhibitory factor and their use in the treatment of human diseases |
| US20060229314A1 (en) | 2005-03-24 | 2006-10-12 | Jagadish Sircar | Thienopyridinone derivatives as macrophage migration inhibitory factor inhibitors |
| GB0605689D0 (en) * | 2006-03-21 | 2006-05-03 | Novartis Ag | Organic compounds |
| AU2018340475B2 (en) | 2017-09-28 | 2023-01-19 | Transthera Sciences (Nanjing), Inc. | PDE9 inhibitor and use thereof |
| KR20210024586A (ko) | 2018-06-27 | 2021-03-05 | 브리스톨-마이어스 스큅 컴퍼니 | T 세포 활성화제로서 유용한 치환된 나프티리디논 화합물 |
| PT3814347T (pt) | 2018-06-27 | 2023-07-18 | Bristol Myers Squibb Co | Compostos de naftiridinona úteis como ativadores de células t |
| AR119821A1 (es) | 2019-08-28 | 2022-01-12 | Bristol Myers Squibb Co | Compuestos de piridopirimidinonilo sustituidos útiles como activadores de células t |
| AR120823A1 (es) | 2019-12-23 | 2022-03-23 | Bristol Myers Squibb Co | Compuestos bicíclicos sustituidos útiles como activadores de células t |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2103805C3 (de) * | 1970-01-28 | 1980-03-20 | Sumitomo Chemical Co., Ltd., Osaka (Japan) | Verfahren zur Herstellung von N-substituierten 6,7-Methylendioxy-4chinolonen |
| CA988522A (en) * | 1972-05-05 | 1976-05-04 | Haydn W.R. Williams | 1,8-naphthyridine compounds |
| US3993656A (en) * | 1974-11-19 | 1976-11-23 | Merck & Co., Inc. | 1,8-Naphthyridine compounds |
| US4103257A (en) * | 1976-05-25 | 1978-07-25 | The United States Of America As Represented By The United States Department Of Energy | Azaquinolone dye lasers |
| US4133885A (en) * | 1977-07-18 | 1979-01-09 | Merck & Co., Inc. | Substituted naphthyridinones |
-
1980
- 1980-02-28 US US06/125,600 patent/US4324893A/en not_active Expired - Lifetime
- 1980-03-19 IL IL59667A patent/IL59667A/xx unknown
- 1980-03-22 GR GR61509A patent/GR67253B/el unknown
- 1980-03-24 WO PCT/US1980/000319 patent/WO1980002287A1/en unknown
- 1980-03-24 JP JP50102580A patent/JPS56500373A/ja active Pending
- 1980-04-10 GB GB8011911A patent/GB2053198B/en not_active Expired
- 1980-04-10 EP EP80301157A patent/EP0018735B1/en not_active Expired
- 1980-04-10 EP EP82200534A patent/EP0060012B1/en not_active Expired
- 1980-04-10 PT PT71081A patent/PT71081A/pt unknown
- 1980-04-11 CA CA349,623A patent/CA1115272A/en not_active Expired
- 1980-04-14 AR AR280667A patent/AR225437A1/es active
- 1980-04-15 IE IE761/80A patent/IE49696B1/en unknown
- 1980-04-15 NZ NZ193445A patent/NZ193445A/xx unknown
- 1980-04-16 AU AU57519/80A patent/AU531348B2/en not_active Ceased
- 1980-04-17 ES ES490645A patent/ES490645A0/es active Granted
- 1980-04-17 FI FI801229A patent/FI801229A/fi not_active Application Discontinuation
- 1980-04-17 YU YU01056/80A patent/YU105680A/xx unknown
- 1980-04-17 KR KR1019800001587A patent/KR840000076B1/ko active
- 1980-04-17 PH PH23914A patent/PH16524A/en unknown
- 1980-04-17 HU HU80935A patent/HU183125B/hu unknown
- 1980-12-10 IN IN1366/CAL/80A patent/IN150969B/en unknown
- 1980-12-17 DK DK537780A patent/DK537780A/da not_active Application Discontinuation
- 1980-12-17 SU SU803220198A patent/SU1131469A3/ru active
-
1981
- 1981-06-16 AR AR285719A patent/AR227427A1/es active
Also Published As
| Publication number | Publication date |
|---|---|
| ES8104286A1 (es) | 1981-04-16 |
| KR830002759A (ko) | 1983-05-30 |
| US4324893A (en) | 1982-04-13 |
| EP0060012B1 (en) | 1984-08-29 |
| GR67253B (es) | 1981-06-26 |
| IE49696B1 (en) | 1985-11-27 |
| AR225437A1 (es) | 1982-03-31 |
| GB2053198B (en) | 1983-04-07 |
| EP0060012A1 (en) | 1982-09-15 |
| IN150969B (es) | 1983-02-05 |
| WO1980002287A1 (en) | 1980-10-30 |
| KR840000076B1 (ko) | 1984-02-08 |
| FI801229A (fi) | 1980-10-19 |
| EP0018735B1 (en) | 1983-07-27 |
| EP0018735A1 (en) | 1980-11-12 |
| AU531348B2 (en) | 1983-08-18 |
| PT71081A (en) | 1980-05-01 |
| ES490645A0 (es) | 1981-04-16 |
| IE800761L (en) | 1980-10-18 |
| CA1115272A (en) | 1981-12-29 |
| YU105680A (en) | 1983-09-30 |
| DK537780A (da) | 1980-12-17 |
| PH16524A (en) | 1983-11-10 |
| IL59667A (en) | 1983-11-30 |
| GB2053198A (en) | 1981-02-04 |
| HU183125B (en) | 1984-04-28 |
| AU5751980A (en) | 1980-10-23 |
| JPS56500373A (es) | 1981-03-26 |
| SU1131469A3 (ru) | 1984-12-23 |
| NZ193445A (en) | 1982-09-07 |
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