ES481209A1 - Un procedimiento para preparar benzoxepinas. - Google Patents

Un procedimiento para preparar benzoxepinas.

Info

Publication number
ES481209A1
ES481209A1 ES481209A ES481209A ES481209A1 ES 481209 A1 ES481209 A1 ES 481209A1 ES 481209 A ES481209 A ES 481209A ES 481209 A ES481209 A ES 481209A ES 481209 A1 ES481209 A1 ES 481209A1
Authority
ES
Spain
Prior art keywords
alkyl
aminoalkylthiodibenzoxepines
preparation
pharmaceutical compositions
compositions containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES481209A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Publication of ES481209A1 publication Critical patent/ES481209A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
    • C07D313/02—Seven-membered rings
    • C07D313/06—Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D313/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
    • C07D313/14—[b,f]-condensed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)

Abstract

1. Un procedimiento para preparar benzoxepinas de la fórmula- 01 (I): **(Fórmula-01)** en la que X e Y son iguales o diferentes y cada uno puede ser hidrógeno, halógeno, trifluorometilo, alcoxi de C1-C6, alcohilo de C1-C6, alcohiltio, alcohilsulfonilo de C1-C6, alcohilsulfinilo de C1-C6, amino o nitro; Z es N -R1 - R2; R1 y R2 son iguales o diferentes y cada uno puede ser alcohilo de C1-C6 de cadena lineal o ramificada, y n es un número entero de 2 a 4; y sales de adición de ácido fisiológicamente tolerables de las mismas, que comprende: reducir un compuesto de la fórmula-02 (Ia): **(Fórmula-02)** en la que X, Y, n son como se han definido en la fórmula I.
ES481209A 1977-12-13 1979-06-01 Un procedimiento para preparar benzoxepinas. Expired ES481209A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US86008377A 1977-12-13 1977-12-13

Publications (1)

Publication Number Publication Date
ES481209A1 true ES481209A1 (es) 1980-09-01

Family

ID=25332451

Family Applications (7)

Application Number Title Priority Date Filing Date
ES475770A Expired ES475770A1 (es) 1977-12-13 1978-12-06 Un procedimiento para preparar benzoxepinas
ES481209A Expired ES481209A1 (es) 1977-12-13 1979-06-01 Un procedimiento para preparar benzoxepinas.
ES481211A Expired ES481211A1 (es) 1977-12-13 1979-06-01 Un procedimiento para preparar benzoxepinas
ES481214A Expired ES481214A1 (es) 1977-12-13 1979-06-01 Un procedimiento para preparar benzoxepinas
ES481210A Expired ES481210A1 (es) 1977-12-13 1979-06-01 Un procedimiento para preparar benzoxepinas.
ES481213A Granted ES481213A0 (es) 1977-12-13 1979-06-01 Un procedimiento para preparar benzoxepinas
ES481212A Expired ES8102116A1 (es) 1977-12-13 1979-06-01 Un procedimiento para preparar benzoxepinas

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES475770A Expired ES475770A1 (es) 1977-12-13 1978-12-06 Un procedimiento para preparar benzoxepinas

Family Applications After (5)

Application Number Title Priority Date Filing Date
ES481211A Expired ES481211A1 (es) 1977-12-13 1979-06-01 Un procedimiento para preparar benzoxepinas
ES481214A Expired ES481214A1 (es) 1977-12-13 1979-06-01 Un procedimiento para preparar benzoxepinas
ES481210A Expired ES481210A1 (es) 1977-12-13 1979-06-01 Un procedimiento para preparar benzoxepinas.
ES481213A Granted ES481213A0 (es) 1977-12-13 1979-06-01 Un procedimiento para preparar benzoxepinas
ES481212A Expired ES8102116A1 (es) 1977-12-13 1979-06-01 Un procedimiento para preparar benzoxepinas

Country Status (8)

Country Link
EP (1) EP0002508B1 (es)
JP (1) JPS5495583A (es)
AT (1) AT369738B (es)
AU (1) AU520460B2 (es)
CA (1) CA1101420A (es)
DE (1) DE2861712D1 (es)
ES (7) ES475770A1 (es)
ZA (1) ZA786957B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4496582A (en) * 1983-12-12 1985-01-29 Hoechst-Roussel Pharmaceuticals Inc. Analgesic dibenz[b,f]oxepins
EP0200132A3 (en) * 1985-04-23 1987-08-26 Hoechst-Roussel Pharmaceuticals Incorporated (aminoalkylthio)hydroxydibenzoxepins, a process for their preparation and their use as medicaments
WO2008096755A1 (ja) * 2007-02-07 2008-08-14 Nippon Suisan Kaisha, Ltd. バニロイド受容体（ｖｒ１）阻害剤及びその用途

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH509306A (de) * 1969-02-14 1971-06-30 Fujisawa Pharmaceutical Co Verfahren zur Herstellung von neuen Dibenzo-oxepinen, -thiepinen und -azepinen

Also Published As

Publication number Publication date
ZA786957B (en) 1979-11-28
ES475770A1 (es) 1980-01-16
EP0002508B1 (de) 1982-03-31
ES481211A1 (es) 1980-09-01
JPS6411632B2 (es) 1989-02-27
ATA883978A (de) 1982-06-15
ES481212A0 (es) 1980-12-16
ES8102117A1 (es) 1980-12-16
EP0002508A1 (de) 1979-06-27
DE2861712D1 (en) 1982-05-06
ES481214A1 (es) 1980-09-01
CA1101420A (en) 1981-05-19
AU4242178A (en) 1979-06-21
ES481210A1 (es) 1980-09-01
ES481213A0 (es) 1980-12-16
AU520460B2 (en) 1982-02-04
ES8102116A1 (es) 1980-12-16
AT369738B (de) 1983-01-25
JPS5495583A (en) 1979-07-28

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