ES481214A1 - Un procedimiento para preparar benzoxepinas - Google Patents

Un procedimiento para preparar benzoxepinas

Info

Publication number
ES481214A1
ES481214A1 ES481214A ES481214A ES481214A1 ES 481214 A1 ES481214 A1 ES 481214A1 ES 481214 A ES481214 A ES 481214A ES 481214 A ES481214 A ES 481214A ES 481214 A1 ES481214 A1 ES 481214A1
Authority
ES
Spain
Prior art keywords
alkyl
aminoalkylthiodibenzoxepines
preparation
pharmaceutical compositions
compositions containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES481214A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Publication of ES481214A1 publication Critical patent/ES481214A1/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D313/00Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
    • C07D313/02Seven-membered rings
    • C07D313/06Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D313/10Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
    • C07D313/14[b,f]-condensed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)

Abstract

1. Un procedimiento para preparar benzoxepinas de la fórmula- 01 (I): **(Fórmula-01)** en la que X e Y son iguales o diferentes y cada uno puede ser hidrógeno, halógeno, trifluorometilo, alcoxi de C1-C6, alcohilo de C1-C6, alcohiltio de C1-C6, alcohilsulfonilo de C1-C6, alcohilsulfinilo de C1-C6, amino o nitro; Z es N -R1 - R2, en donde R1 es alcohilo de C1-C6 de cadena lineal o ramificada, cicloalcohil-alcohilo de C1-C6, en el que el anillo de cicloalcohilo contiene de 3 a 6 átomos de carbono, alquenilo de C2-C6 o alquinilo de C2-C6; R2es alcohilo de C1- c6 de cadena lineal o ramificada; m es el número entero 0 ó 1; y n es un número entero de 2 a 4; y una sal de adición de ácido fisiológicamente tolerable de las mismas, que comprende: hacer reaccionar un compuesto de la fórmula-02 (Ia): **(Fórmula-02)** en la que X, Y, m y n son como se han definido en la fórmula I, R1 es hidrógeno y R2 es un alcohilo de C1-C6 de cadena lineal o ramificada, con un haluro de alcohilo de C1-C6 de cadena lineal o ramificada, haluro de alquenilo de C2-C6, haluro de alquinilo de C2-C6 o haluro de cicloalcohil-alcohilo de C1-C6-
ES481214A 1977-12-13 1979-06-01 Un procedimiento para preparar benzoxepinas Expired ES481214A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US86008377A 1977-12-13 1977-12-13

Publications (1)

Publication Number Publication Date
ES481214A1 true ES481214A1 (es) 1980-09-01

Family

ID=25332451

Family Applications (7)

Application Number Title Priority Date Filing Date
ES475770A Expired ES475770A1 (es) 1977-12-13 1978-12-06 Un procedimiento para preparar benzoxepinas
ES481209A Expired ES481209A1 (es) 1977-12-13 1979-06-01 Un procedimiento para preparar benzoxepinas.
ES481212A Granted ES481212A0 (es) 1977-12-13 1979-06-01 Un procedimiento para preparar benzoxepinas
ES481211A Expired ES481211A1 (es) 1977-12-13 1979-06-01 Un procedimiento para preparar benzoxepinas
ES481210A Expired ES481210A1 (es) 1977-12-13 1979-06-01 Un procedimiento para preparar benzoxepinas.
ES481214A Expired ES481214A1 (es) 1977-12-13 1979-06-01 Un procedimiento para preparar benzoxepinas
ES481213A Expired ES8102117A1 (es) 1977-12-13 1979-06-01 Un procedimiento para preparar benzoxepinas

Family Applications Before (5)

Application Number Title Priority Date Filing Date
ES475770A Expired ES475770A1 (es) 1977-12-13 1978-12-06 Un procedimiento para preparar benzoxepinas
ES481209A Expired ES481209A1 (es) 1977-12-13 1979-06-01 Un procedimiento para preparar benzoxepinas.
ES481212A Granted ES481212A0 (es) 1977-12-13 1979-06-01 Un procedimiento para preparar benzoxepinas
ES481211A Expired ES481211A1 (es) 1977-12-13 1979-06-01 Un procedimiento para preparar benzoxepinas
ES481210A Expired ES481210A1 (es) 1977-12-13 1979-06-01 Un procedimiento para preparar benzoxepinas.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES481213A Expired ES8102117A1 (es) 1977-12-13 1979-06-01 Un procedimiento para preparar benzoxepinas

Country Status (8)

Country Link
EP (1) EP0002508B1 (es)
JP (1) JPS5495583A (es)
AT (1) AT369738B (es)
AU (1) AU520460B2 (es)
CA (1) CA1101420A (es)
DE (1) DE2861712D1 (es)
ES (7) ES475770A1 (es)
ZA (1) ZA786957B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4496582A (en) * 1983-12-12 1985-01-29 Hoechst-Roussel Pharmaceuticals Inc. Analgesic dibenz[b,f]oxepins
ES8706660A1 (es) * 1985-04-23 1987-07-01 Hoechst Roussel Pharma Un procedimiento para preparar (aminoalquiltio)hidroxidibenzoxepinas
WO2008096755A1 (ja) * 2007-02-07 2008-08-14 Nippon Suisan Kaisha, Ltd. バニロイド受容体(vr1)阻害剤及びその用途

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH509306A (de) * 1969-02-14 1971-06-30 Fujisawa Pharmaceutical Co Verfahren zur Herstellung von neuen Dibenzo-oxepinen, -thiepinen und -azepinen

Also Published As

Publication number Publication date
JPS6411632B2 (es) 1989-02-27
EP0002508A1 (de) 1979-06-27
ES8102116A1 (es) 1980-12-16
ES475770A1 (es) 1980-01-16
JPS5495583A (en) 1979-07-28
ES481210A1 (es) 1980-09-01
ZA786957B (en) 1979-11-28
CA1101420A (en) 1981-05-19
ES481212A0 (es) 1980-12-16
ES481213A0 (es) 1980-12-16
ES481209A1 (es) 1980-09-01
EP0002508B1 (de) 1982-03-31
DE2861712D1 (en) 1982-05-06
ES8102117A1 (es) 1980-12-16
ES481211A1 (es) 1980-09-01
AT369738B (de) 1983-01-25
AU4242178A (en) 1979-06-21
ATA883978A (de) 1982-06-15
AU520460B2 (en) 1982-02-04

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