ES482591A1 - Procedimiento para la obtencion de n-arilsulfonilpirroles. - Google Patents
Procedimiento para la obtencion de n-arilsulfonilpirroles.Info
- Publication number
- ES482591A1 ES482591A1 ES482591A ES482591A ES482591A1 ES 482591 A1 ES482591 A1 ES 482591A1 ES 482591 A ES482591 A ES 482591A ES 482591 A ES482591 A ES 482591A ES 482591 A1 ES482591 A1 ES 482591A1
- Authority
- ES
- Spain
- Prior art keywords
- carbon atoms
- unsubstituted
- hydrogen
- heterocyclic ring
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/28—Halogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/46—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with hetero atoms directly attached to the ring nitrogen atom
- C07D207/48—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Procedimiento para la obtención N- arilsulfonilpirroles de la fórmula 1 **(Fórmula- 01)** en la cual R es un radical alifático saturado, en caso dado sustituido con 1 hasta 8 átomos de carbono, un radical alquilo no saturado con 2 hasta 8 átomos de carbono, un radical cicloalquilo con 3 hasta 7 átomos de C en el anillo, un radical alquilo con 1 hasta 4 átomos de C que está sustituido por fenilo o un anillo aromático heterocíclico con 5 ó 6 eslabones y un átomo de N, O o S, pudiendo el anillo fenilo o el anillo heterocíclico estar mono hasta polisustituidos, R2 es un átomo de hidrógeno R1 y R2 forman junto con el átomo de nitrógeno un anillo cicloalifático con 4 hasta 6 eslabones.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19782831850 DE2831850A1 (de) | 1978-07-20 | 1978-07-20 | N-arylsulfonylpyrrole, ihre herstellung und diese enthaltende therapeutische mittel |
DE19792914615 DE2914615A1 (de) | 1979-04-11 | 1979-04-11 | Dialkyl-n-arylsulfonylpyrrole, ihre herstellung und diese enthaltende arzneimittel |
Publications (1)
Publication Number | Publication Date |
---|---|
ES482591A1 true ES482591A1 (es) | 1980-04-01 |
Family
ID=25775081
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES482591A Expired ES482591A1 (es) | 1978-07-20 | 1979-07-18 | Procedimiento para la obtencion de n-arilsulfonilpirroles. |
Country Status (5)
Country | Link |
---|---|
US (1) | US4288449A (es) |
EP (1) | EP0008367B1 (es) |
CA (1) | CA1135705A (es) |
DE (1) | DE2966048D1 (es) |
ES (1) | ES482591A1 (es) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3279368D1 (en) * | 1981-12-18 | 1989-02-23 | Ciba Geigy Ag | Microbicidal sulfonyl pyrrole |
FR2553409B1 (fr) * | 1983-10-18 | 1986-04-18 | Choay Sa | Nouveaux benzenesulfonyl-lactames, leur procede de preparation et leur application comme substance active de compositions pharmaceutiques |
US5288677A (en) * | 1991-06-28 | 1994-02-22 | Exxon Chemical Patents Inc. | Immobilized Lewis acid catalysts |
NZ596413A (en) | 2006-04-11 | 2013-03-28 | Vertex Pharma | Phenyl-sulfinyl-sulfamoylphenyl-benzamide derivatives that inhibit voltage-gated sodium channels |
NZ584475A (en) * | 2007-10-11 | 2012-07-27 | Vertex Pharma | Heteroaryl amides useful as inhibitors of voltage-gated sodium channels |
CA2701766A1 (en) | 2007-10-11 | 2009-04-16 | Vertex Pharmaceuticals Incorporated | Amides useful as inhibitors of voltage-gated sodium channels |
NZ584519A (en) * | 2007-10-11 | 2012-07-27 | Vertex Pharma | Aryl amides useful as inhibitors of voltage-gated sodium channels |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IE33874B1 (en) * | 1968-12-24 | 1974-11-27 | Leo Pharm Prod Ltd | New sulphamyl-benzoic acid derivatives |
GB1249490A (en) * | 1968-12-24 | 1971-10-13 | Leo Pharm Prod Ltd | New sulphamyl-benzoic acid derivatives |
BE756626A (fr) * | 1969-09-26 | 1971-03-25 | Merck & Co Inc | Benzenesulfonamides |
NL7411618A (nl) * | 1973-09-07 | 1975-03-11 | Hoechst Ag | Werkwijze voor het bereiden van gesubstitueerde aminobenzoezuurderivaten. |
DE2453548A1 (de) * | 1973-09-07 | 1976-03-18 | Hoechst Ag | Substituierte aminobenzoesaeurederivate und verfahren zu ihrer herstellung |
DE2419970C3 (de) * | 1974-04-25 | 1980-06-12 | Hoechst Ag, 6000 Frankfurt | 3-<l-Pyrrolidinyl)-4-phenoxy-5sulfamoylbenzoesäure und Verfahren zu ihrer Herstellung |
US4093735A (en) * | 1974-04-25 | 1978-06-06 | Hoechst Aktiengesellschaft | 5-Sulfamoylbenzoic acid derivatives carrying a heterocyclic substituent |
DE2518999A1 (de) * | 1975-04-29 | 1976-11-18 | Hoechst Ag | Verfahren zur herstellung von sulfamylbenzoesaeuren |
CH628622A5 (de) * | 1976-12-24 | 1982-03-15 | Ciba Geigy Ag | Verfahren zur herstellung von neuen in 4-stellung substituierten 3-sulfamoylbenzoesaeuren. |
-
1979
- 1979-07-18 EP EP79102522A patent/EP0008367B1/de not_active Expired
- 1979-07-18 CA CA000332072A patent/CA1135705A/en not_active Expired
- 1979-07-18 DE DE7979102522T patent/DE2966048D1/de not_active Expired
- 1979-07-18 ES ES482591A patent/ES482591A1/es not_active Expired
-
1980
- 1980-05-28 US US06/154,036 patent/US4288449A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP0008367B1 (de) | 1983-08-10 |
CA1135705A (en) | 1982-11-16 |
US4288449A (en) | 1981-09-08 |
DE2966048D1 (en) | 1983-09-15 |
EP0008367A1 (de) | 1980-03-05 |
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