ES478803A1 - Un procedimiento para la preparacion de derivados de acila- dos de muramil peptidos. - Google Patents
Un procedimiento para la preparacion de derivados de acila- dos de muramil peptidos.Info
- Publication number
- ES478803A1 ES478803A1 ES79478803A ES478803A ES478803A1 ES 478803 A1 ES478803 A1 ES 478803A1 ES 79478803 A ES79478803 A ES 79478803A ES 478803 A ES478803 A ES 478803A ES 478803 A1 ES478803 A1 ES 478803A1
- Authority
- ES
- Spain
- Prior art keywords
- muramyl
- reactants
- laboratory
- application
- ester derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000002148 esters Chemical class 0.000 title 1
- 239000008196 pharmacological composition Substances 0.000 title 1
- 239000000376 reactant Substances 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 125000001446 muramyl group Chemical group N[C@@H](C=O)[C@@H](O[C@@H](C(=O)*)C)[C@H](O)[C@H](O)CO 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
- C07K9/001—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure
- C07K9/005—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure containing within the molecule the substructure with m, n > 0 and m+n > 0, A, B, D, E being heteroatoms; X being a bond or a chain, e.g. muramylpeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmacology & Pharmacy (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Crystallography & Structural Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Genetics & Genomics (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Abstract
La invención se refiere a nuevos productos dotados de propiedades biológicas y farmacológicas de gran valor, los cuales pueden ser útiles bien sea para la constitución de reactivos de laboratorio estandarizados para el estudio comparativo de las propiedades biológicas parecidas de otros compuestos, o para la constitución de medicamentos nuevos pasa uso humano o veterinario.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7808049A FR2420545A1 (fr) | 1978-03-20 | 1978-03-20 | Nouveaux esters de l'acide n-acetyl-muramyl-aminoacyl-glutamique ou des derives de substitution de celui-ci a proprietes anti-infectieuses et/ou d'adjuvants immunologiques |
FR7833126A FR2442241A2 (fr) | 1978-03-20 | 1978-11-23 | Nouveaux composes esters de muramyl-peptide, leur preparation et les compositions pharmaceutiques les contenant, notamment sous forme de liposomes |
Publications (1)
Publication Number | Publication Date |
---|---|
ES478803A1 true ES478803A1 (es) | 1979-12-16 |
Family
ID=26220504
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES79478803A Expired ES478803A1 (es) | 1978-03-20 | 1979-03-20 | Un procedimiento para la preparacion de derivados de acila- dos de muramil peptidos. |
Country Status (5)
Country | Link |
---|---|
US (1) | US4396607A (es) |
EP (1) | EP0004512B1 (es) |
DE (1) | DE2966538D1 (es) |
ES (1) | ES478803A1 (es) |
FR (1) | FR2442241A2 (es) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS55111499A (en) * | 1979-02-21 | 1980-08-28 | Takeda Chem Ind Ltd | Glucosamine derivative and its preparation |
JPS5618996A (en) * | 1979-06-21 | 1981-02-23 | Dai Ichi Seiyaku Co Ltd | Muramyldipeptide derivative |
US4409209A (en) * | 1979-10-12 | 1983-10-11 | Ciba-Geigy Corporation | Novel phosphorylmuramyl peptides and processes for the manufacture thereof |
US4406889A (en) * | 1980-02-15 | 1983-09-27 | Ciba-Geigy Corporation | Derivatives of aldohexoses, intermediates, processes for their manufacture, preparations containing such compounds, and their use |
US4368190A (en) * | 1980-04-17 | 1983-01-11 | Merck & Co., Inc. | Immunologically active dipeptidyl 4-O-,6-O-acyl-2-amino-2-deoxy-D-glucose derivatives and methods for their preparation |
FR2551758B1 (fr) * | 1983-08-16 | 1986-01-31 | Anvar | Derives de muramyl-peptides et de steroides ayant des proprietes d'activation des macrophages |
JPS6042398A (ja) * | 1983-08-18 | 1985-03-06 | Toshiyuki Hamaoka | ムラミルジペプチド活性エステル誘導体 |
US5171568A (en) * | 1984-04-06 | 1992-12-15 | Chiron Corporation | Recombinant herpes simplex gb-gd vaccine |
ZA853989B (en) * | 1984-05-29 | 1986-01-29 | Ciba Geigy Ag | Acylated sugar derivatives,processes for their manufacture,and their use |
EP0204775A4 (en) * | 1984-12-14 | 1989-10-04 | Univ Trobe | AMINO ACID AND PEPTIDE INHIBITORS FOR HUMAN LEUKOCYTELASTASE. |
FI860708A (fi) * | 1985-02-20 | 1986-08-21 | Ciba Geigy Ag | Acylerade hexosderivat och foerfarande foer deras framstaellning. |
EP0192609A3 (de) * | 1985-02-20 | 1988-04-27 | Ciba-Geigy Ag | Acylierte Hexosederivate und Verfahren zu ihrer Herstellung |
US4640911A (en) * | 1985-05-29 | 1987-02-03 | Ciba-Geigy Corporation | Acylated sugar derivatives, processes for their manufacture, and their use |
US4938947A (en) * | 1985-11-01 | 1990-07-03 | Centre National De La Recherche Scientifique (Cnrs) | Aerosol composition for in vivo imaging |
US5017359A (en) * | 1985-11-01 | 1991-05-21 | Centre National De La Recherche Scientifique | Aerosol compositions for in vivo imaging and therapy |
US4792555A (en) * | 1987-03-20 | 1988-12-20 | American Home Products Corporation | Phospholipase A2 inhibitors |
US5416070A (en) * | 1988-07-08 | 1995-05-16 | Immunotherapeutics, Inc. | Composition for macrophage activation |
US4950645A (en) * | 1988-07-08 | 1990-08-21 | Immunotherapeutics, Inc. | Composition for macrophage activation |
HU205147B (en) * | 1989-06-29 | 1992-03-30 | Sandoz Ag | Process for producing muramyl dipeptide derivative and pharmaceutical compostions comprising same |
EP2061490B1 (en) * | 2006-08-25 | 2017-11-08 | Agency for Science, Technology and Research | Modulators of candida hyphal morphogenesis and uses thereof |
US10610564B2 (en) | 2015-02-26 | 2020-04-07 | Stc.Unm | IRGM and precision autophagy controls for antimicrobial and inflammatory disease states and methods of detection of autophagy |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3833C (de) * | W. RlEHN, Civil-Ingenieur, in Görlitz | Expansionssteuerung für Förder-Maschinen | ||
FR554486A (fr) * | 1922-07-26 | 1923-06-12 | Ets Ballot Sa | Came perfectionnée pour la commande de freins sur roues avant de voiture automobile |
GB1564500A (en) * | 1975-09-29 | 1980-04-10 | Wellcome Found | Biological preparations |
CH613709A5 (en) * | 1975-12-10 | 1979-10-15 | Ciba Geigy Ag | Process for the preparation of glucosamine derivatives |
US4153684A (en) * | 1976-03-10 | 1979-05-08 | Agence Nationale De Valorisation De La Recherche (Anvar) | Immunizing and anti-infectious adjuvant agents constituted by N-acetyl-muramyl-L-alanyl-D-glutamic acid derivatives |
NL7702579A (nl) * | 1976-03-10 | 1977-09-13 | Anvar | Werkwijze ter bereiding van immuniserende en anti- infectieuze middelen. |
GB1571133A (en) * | 1976-04-26 | 1980-07-09 | Syntex Inc | Immuniological adjuvant peptidoglycans compounds and methods of preparation thereof |
-
1978
- 1978-11-23 FR FR7833126A patent/FR2442241A2/fr active Granted
-
1979
- 1979-03-20 EP EP79400183A patent/EP0004512B1/fr not_active Expired
- 1979-03-20 DE DE7979400183T patent/DE2966538D1/de not_active Expired
- 1979-03-20 ES ES79478803A patent/ES478803A1/es not_active Expired
-
1981
- 1981-05-01 US US06/259,450 patent/US4396607A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP0004512A1 (fr) | 1979-10-03 |
EP0004512B1 (fr) | 1984-01-18 |
DE2966538D1 (en) | 1984-02-23 |
FR2442241B2 (es) | 1983-04-22 |
FR2442241A2 (fr) | 1980-06-20 |
US4396607A (en) | 1983-08-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 19960603 |