ES477786A1 - Alkynylaminosulphonyl-substituted benzamides process for their preparation and pharmaceutical compositions containing them - Google Patents
Alkynylaminosulphonyl-substituted benzamides process for their preparation and pharmaceutical compositions containing themInfo
- Publication number
- ES477786A1 ES477786A1 ES477786A ES477786A ES477786A1 ES 477786 A1 ES477786 A1 ES 477786A1 ES 477786 A ES477786 A ES 477786A ES 477786 A ES477786 A ES 477786A ES 477786 A1 ES477786 A1 ES 477786A1
- Authority
- ES
- Spain
- Prior art keywords
- alkynylaminosulphonyl
- preparation
- pharmaceutical compositions
- compositions containing
- substituted benzamides
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229940054066 benzamide antipsychotics Drugs 0.000 title 1
- 150000003936 benzamides Chemical class 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical compound OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 239000005711 Benzoic acid Substances 0.000 abstract 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical group [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
- 208000012545 Psychophysiologic disease Diseases 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 125000004202 aminomethyl group Chemical group [H]N([H])C([H])([H])* 0.000 abstract 1
- 235000010233 benzoic acid Nutrition 0.000 abstract 1
- 230000000295 complement effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000005494 condensation Effects 0.000 abstract 1
- 238000009833 condensation Methods 0.000 abstract 1
- 125000004122 cyclic group Chemical group 0.000 abstract 1
- 125000004985 dialkyl amino alkyl group Chemical group 0.000 abstract 1
- 230000001079 digestive effect Effects 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 150000002431 hydrogen Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
- C07D207/09—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Hydrogenated Pyridines (AREA)
- Pyrrole Compounds (AREA)
Abstract
The compounds of formula: < IMAGE > in which R represents certain linear or cyclic dialkylaminoalkyl groups, X in position 2, 3 or 4 represents a hydrogen, halogen or alkoxy, R1 and R2 represent hydrogens or alkyls or, taken together, the complement of a carbon ring and R3 represents a hydrogen or certain substituted aminomethyl groups, and their salts with acids, can be used in the treatment of digestive and psychosomatic disorders. They are prepared by condensation of an amine R-NH2 with a benzoic acid corresponding to the above formula.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7715205A FR2391195A1 (en) | 1977-05-16 | 1977-05-16 | BENZAMIDE ACETYLENIC SULFAMIDO FOR THERAPEUTIC USE |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES477786A1 true ES477786A1 (en) | 1979-10-16 |
Family
ID=9190977
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES469708A Expired ES469708A1 (en) | 1977-05-16 | 1978-05-11 | Alkynylaminosulphonyl-substituted benzamides process for their preparation and pharmaceutical compositions containing them |
| ES477786A Expired ES477786A1 (en) | 1977-05-16 | 1979-02-16 | Alkynylaminosulphonyl-substituted benzamides process for their preparation and pharmaceutical compositions containing them |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES469708A Expired ES469708A1 (en) | 1977-05-16 | 1978-05-11 | Alkynylaminosulphonyl-substituted benzamides process for their preparation and pharmaceutical compositions containing them |
Country Status (10)
| Country | Link |
|---|---|
| JP (1) | JPS53144542A (en) |
| BE (1) | BE867097A (en) |
| CA (1) | CA1105053A (en) |
| CH (1) | CH620674A5 (en) |
| DE (1) | DE2818323A1 (en) |
| ES (2) | ES469708A1 (en) |
| FR (1) | FR2391195A1 (en) |
| GB (1) | GB1591770A (en) |
| IT (1) | IT1159672B (en) |
| NL (1) | NL7805235A (en) |
-
1977
- 1977-05-16 FR FR7715205A patent/FR2391195A1/en active Granted
-
1978
- 1978-04-26 DE DE19782818323 patent/DE2818323A1/en not_active Withdrawn
- 1978-05-11 ES ES469708A patent/ES469708A1/en not_active Expired
- 1978-05-12 CH CH524478A patent/CH620674A5/en not_active IP Right Cessation
- 1978-05-15 IT IT68111/78A patent/IT1159672B/en active
- 1978-05-16 JP JP5812578A patent/JPS53144542A/en active Pending
- 1978-05-16 NL NL7805235A patent/NL7805235A/en not_active Application Discontinuation
- 1978-05-16 BE BE187713A patent/BE867097A/en unknown
- 1978-05-16 GB GB19809/78A patent/GB1591770A/en not_active Expired
- 1978-05-16 CA CA303,521A patent/CA1105053A/en not_active Expired
-
1979
- 1979-02-16 ES ES477786A patent/ES477786A1/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| FR2391195B1 (en) | 1982-09-17 |
| ES469708A1 (en) | 1979-09-16 |
| BE867097A (en) | 1978-09-18 |
| CH620674A5 (en) | 1980-12-15 |
| FR2391195A1 (en) | 1978-12-15 |
| DE2818323A1 (en) | 1978-11-30 |
| IT1159672B (en) | 1987-03-04 |
| IT7868111A0 (en) | 1978-05-15 |
| GB1591770A (en) | 1981-06-24 |
| NL7805235A (en) | 1978-11-20 |
| CA1105053A (en) | 1981-07-14 |
| JPS53144542A (en) | 1978-12-15 |
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