ES8404972A1 - Aminophenylalkylamine derivatives, a process for their preparation and their use as pharmaceuticals - Google Patents
Aminophenylalkylamine derivatives, a process for their preparation and their use as pharmaceuticalsInfo
- Publication number
- ES8404972A1 ES8404972A1 ES512788A ES512788A ES8404972A1 ES 8404972 A1 ES8404972 A1 ES 8404972A1 ES 512788 A ES512788 A ES 512788A ES 512788 A ES512788 A ES 512788A ES 8404972 A1 ES8404972 A1 ES 8404972A1
- Authority
- ES
- Spain
- Prior art keywords
- hydrogen
- c4alkyl
- c4alkoxy
- halogen
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Abstract
Compounds of formula I < IMAGE > in which R1 represents hydrogen, halogen, C1-C4alkyl or C1-C4alkoxy, R2 represents hydrogen, halogen, C1-C4alkyl, C1-C4alkoxy or a group of formula < IMAGE > wherein A represents oxygen, sulphur, carbonyl or a direct bond and R8 and R9, independently, represent hydrogen, halogen, C1-C4alkyl or C1-C4alkoxy R3 represents hydrogen or C1-C4alkyl, n is 0, 1 or 2, R4 represents C4-C24alkyl, R5 represents hydrogen, C1-C24alkyl or a group physiologically degradable to a hydrogen atom and R6 and R7 represent, independently, hydrogen, C1-C24alkyl, a group of formula < IMAGE > wherein B represents C1-C6alkylene and R10 and R11 represent, independently, hydrogen, halogen, C1-C4alkyl or C1-C4alkoxy or a group physiologically degradable to a hydrogen atom and the nitrogen containing groups are in meta- or para-position to each other and pharmaceutically acceptable acid addition salts thereof. The compounds are indicated for use in inhibiting hyperglycemia, for example in patients suffering from diabetes.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US27102281A | 1981-06-05 | 1981-06-05 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES512788A0 ES512788A0 (en) | 1984-05-16 |
| ES8404972A1 true ES8404972A1 (en) | 1984-05-16 |
Family
ID=23033859
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES512788A Expired ES8404972A1 (en) | 1981-06-05 | 1982-06-02 | Aminophenylalkylamine derivatives, a process for their preparation and their use as pharmaceuticals |
Country Status (15)
| Country | Link |
|---|---|
| JP (1) | JPS584749A (en) |
| AU (1) | AU8444982A (en) |
| BE (1) | BE893367A (en) |
| DE (1) | DE3220185A1 (en) |
| DK (1) | DK253882A (en) |
| ES (1) | ES8404972A1 (en) |
| FI (1) | FI821896A0 (en) |
| FR (1) | FR2507180A1 (en) |
| GB (1) | GB2100261B (en) |
| IL (1) | IL65965A0 (en) |
| IT (1) | IT1189293B (en) |
| NL (1) | NL8202227A (en) |
| PT (1) | PT74994B (en) |
| SE (1) | SE8203477L (en) |
| ZA (1) | ZA823950B (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5312924A (en) | 1983-12-30 | 1994-05-17 | Dr. Karl Thomae Gmbh | Phenylacetic acid benzylamides |
| DE102007028109A1 (en) | 2007-06-19 | 2008-12-24 | Märkisches Werk GmbH | Thermally sprayed, gas-tight protective layer for metallic substrates |
| JP6054108B2 (en) | 2012-09-07 | 2016-12-27 | 高砂香料工業株式会社 | Process for producing optically active 2,3-dihydrofarnesal |
| WO2019009317A1 (en) * | 2017-07-05 | 2019-01-10 | 日産化学株式会社 | Benzyl compound |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE613948A (en) * | 1961-02-15 |
-
1982
- 1982-05-28 FI FI821896A patent/FI821896A0/en not_active Application Discontinuation
- 1982-05-28 DE DE19823220185 patent/DE3220185A1/en not_active Withdrawn
- 1982-06-01 FR FR8209627A patent/FR2507180A1/en active Granted
- 1982-06-01 GB GB8215985A patent/GB2100261B/en not_active Expired
- 1982-06-01 BE BE1/10523A patent/BE893367A/en not_active IP Right Cessation
- 1982-06-02 NL NL8202227A patent/NL8202227A/en not_active Application Discontinuation
- 1982-06-02 ES ES512788A patent/ES8404972A1/en not_active Expired
- 1982-06-03 PT PT74994A patent/PT74994B/en unknown
- 1982-06-03 IL IL65965A patent/IL65965A0/en unknown
- 1982-06-03 AU AU84449/82A patent/AU8444982A/en not_active Abandoned
- 1982-06-04 ZA ZA823950A patent/ZA823950B/en unknown
- 1982-06-04 JP JP57096865A patent/JPS584749A/en active Pending
- 1982-06-04 SE SE8203477A patent/SE8203477L/en not_active Application Discontinuation
- 1982-06-04 DK DK253882A patent/DK253882A/en not_active Application Discontinuation
- 1982-06-04 IT IT48593/82A patent/IT1189293B/en active
Also Published As
| Publication number | Publication date |
|---|---|
| FR2507180B1 (en) | 1984-07-20 |
| DE3220185A1 (en) | 1982-12-23 |
| NL8202227A (en) | 1983-01-03 |
| ES512788A0 (en) | 1984-05-16 |
| PT74994A (en) | 1982-07-01 |
| GB2100261A (en) | 1982-12-22 |
| IL65965A0 (en) | 1982-09-30 |
| PT74994B (en) | 1985-01-07 |
| ZA823950B (en) | 1984-01-25 |
| SE8203477L (en) | 1982-12-06 |
| GB2100261B (en) | 1985-05-01 |
| FR2507180A1 (en) | 1982-12-10 |
| JPS584749A (en) | 1983-01-11 |
| AU8444982A (en) | 1982-12-09 |
| IT1189293B (en) | 1988-02-04 |
| BE893367A (en) | 1982-12-01 |
| FI821896A0 (en) | 1982-05-28 |
| DK253882A (en) | 1982-12-06 |
| IT8248593A0 (en) | 1982-06-04 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NZ504336A (en) | Tetrahydrofuran substituted adenosine A1 receptor agonists, pharmaceuticals thereof, and their use as medicaments | |
| HUP9901652A2 (en) | Use of piperidine-carboxylic acid derivatives for producing pharmaceutical compositions suitable for reducing blood glucose | |
| ES473451A1 (en) | Imidazole derivatives their synthesis and their pharmaceutical formulations. | |
| ZA919181B (en) | Oxazolopyridine derivatives,processes for preparing these and pharmaceutical compositions containing them | |
| MY102866A (en) | Amide derivatives. | |
| ES8203883A1 (en) | Imidazole derivatives, their preparation and compositions containing them. | |
| ATE19878T1 (en) | BENZIMIDAZOLE DERIVATIVES, PROCESS FOR THEIR MANUFACTURE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. | |
| ES8705371A1 (en) | Aminopropanol derivatives, process for their preparation, their use and medicines containing them. | |
| ATE59033T1 (en) | N-CONTAINING HETEROCYCLIC COMPOUNDS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICALS CONTAINING THEM. | |
| MY105538A (en) | Derivatives of thieno-triazolo-diazepine, a preparation process of the same and therapeutic compositions containing them. | |
| ATE106073T1 (en) | IRON CITRATE COMPLEX, PROCESS FOR ITS PREPARATION AND ITS PHARMACEUTICAL USE. | |
| GR3023934T3 (en) | New naphthalene amides and sulfonamides, process for their preparation and pharmaceutical compositions containing them | |
| ES8404972A1 (en) | Aminophenylalkylamine derivatives, a process for their preparation and their use as pharmaceuticals | |
| ES8606880A1 (en) | Novel peptides and process for preparing the same and pharmaceutical composition. | |
| ZA912618B (en) | 3-aminochroman derivatives,process for preparing these and pharmaceutical compositions containing them | |
| ATE44142T1 (en) | ISOXAZOLE DERIVATIVES, PROCESSES FOR THEIR PRODUCTION AND PHARMACEUTICALS CONTAINING THESE COMPOUNDS. | |
| ATE53209T1 (en) | PIPERAZINE COMPOUNDS, PROCESS FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITION AND USE. | |
| ES8604960A1 (en) | 1,6-Naphthyridine derivatives, process for their preparation and medicament containing them. | |
| DE3787844T2 (en) | Thioester and its use in the manufacture of pharmaceutical compositions for the treatment of ischemia and reperfusion syndromes. | |
| HUT41025A (en) | Process for preparing octahydro-indolizine derivatives and pharmaceutical compositions containing such compounds as active ingredients | |
| ATE98235T1 (en) | 2-THIAZOLIDINONE DERIVATIVES AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM, PROCESSES FOR THEIR MANUFACTURE AND THEIR USE. | |
| DE58902884D1 (en) | THIENYLOXY ALKYLAMINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS. | |
| ATE45958T1 (en) | PEPTIDES, COMPOSITIONS CONTAINING THEM AND PROCESSES FOR THEIR PREPARATION. | |
| GR3021765T3 (en) | Aminoalkylchomones, process for their preparation and pharmaceutical compositions containing them. | |
| ES8201575A1 (en) | Novel 2-aminoethanol, manufacture and hypotensive and analgesic medicine containing same |