ES477421A1 - Procedimiento para la preparacion de acidos3-(2-(n-alcohil- inferior-benzamido)-fenil)-alcanoicos. - Google Patents

Procedimiento para la preparacion de acidos3-(2-(n-alcohil- inferior-benzamido)-fenil)-alcanoicos.

Info

Publication number
ES477421A1
ES477421A1 ES477421A ES477421A ES477421A1 ES 477421 A1 ES477421 A1 ES 477421A1 ES 477421 A ES477421 A ES 477421A ES 477421 A ES477421 A ES 477421A ES 477421 A1 ES477421 A1 ES 477421A1
Authority
ES
Spain
Prior art keywords
group
lower alkyl
denotes
halogen atom
phenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES477421A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda GmbH
Original Assignee
Byk Gulden Lomberg Chemische Fabrik GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Byk Gulden Lomberg Chemische Fabrik GmbH filed Critical Byk Gulden Lomberg Chemische Fabrik GmbH
Publication of ES477421A1 publication Critical patent/ES477421A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16—Benzazepines; Hydrogenated benzazepines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

1. Procedimiento para la preparación de ácidos w-[2.(N-alcohil inferior-benzamido)-fenil]-alcohoicos de la fórmula general I **(Fórmula)** en donde n significa un número entero positivo de 7 a 5, R significa un átomo de hidrógeno, un átomo halógeno, un grupo alcohilo inferior, un grupo alcoxi inferior, un grupo alcohil marcapto inferior, un grupo trifluoromatilo o un grupo fenilo eventualmente sustituido con un átomo de halógeno o un grupo alcoxi inferior; R2 significa un átomo de hidrógeno, un átomo de halógeno, un grupo alcohilo inferior o un grupo alcoxi inferior; R3 significa un grupo alcohilo inferior; R4 significa un átomo de hidrógeno, un átomo de halógeno, un grupo hidroxi, un grupo alcohilo inferior, un grupo alcoxi inferior, un grupo alcohil mercapto inferior, un grupo fenilo eventualmente sustituido con un átomo de halógeno o con un grupo nitro, un grupo nitro, un grupo amino eventualmente sustituido con alcohilo inferior, un grupo alcohil inferior- carbonilo, un grupo benzoilo eventualmente sustituido con un átomo de halógeno, un grupo trifluorometilo, un grupo trifluoromatoxi o un grupo trifluorometilmercapto, R5 significa un átomo de hidrógeno, un átomo de halógeno, un grupo alcohilo inferior o un grupo alcoxi inferior, R6 significa un átomo de hidrógeno, un grupo alcohilo inferior o un grupo alcoxi inferior, y sus sales con bases orgánicas o inorgánicas.
ES477421A 1978-02-03 1979-02-02 Procedimiento para la preparacion de acidos3-(2-(n-alcohil- inferior-benzamido)-fenil)-alcanoicos. Expired ES477421A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
LU79008A LU79008A1 (de) 1978-02-03 1978-02-03 W-(n-alkyl-n-benzoyl-amino)-phenylalkansaeuren,ihre verwendung und herstellung sowie sie enthaltende arzneimittel

Publications (1)

Publication Number Publication Date
ES477421A1 true ES477421A1 (es) 1980-08-16

Family

ID=19728834

Family Applications (3)

Application Number Title Priority Date Filing Date
ES477421A Expired ES477421A1 (es) 1978-02-03 1979-02-02 Procedimiento para la preparacion de acidos3-(2-(n-alcohil- inferior-benzamido)-fenil)-alcanoicos.
ES487989A Expired ES8102089A1 (es) 1978-02-03 1980-01-24 Procedimiento para la preparacion de acidos w-(2-(n-alcohil inferior-benzamido)-fenil)-alcanoicos
ES487990A Granted ES487990A0 (es) 1978-02-03 1980-01-24 Procedimiento para la preparacion de acidos w-(2-(n-alcohil inferior-benzamido)-fenil)-alcanoicos

Family Applications After (2)

Application Number Title Priority Date Filing Date
ES487989A Expired ES8102089A1 (es) 1978-02-03 1980-01-24 Procedimiento para la preparacion de acidos w-(2-(n-alcohil inferior-benzamido)-fenil)-alcanoicos
ES487990A Granted ES487990A0 (es) 1978-02-03 1980-01-24 Procedimiento para la preparacion de acidos w-(2-(n-alcohil inferior-benzamido)-fenil)-alcanoicos

Country Status (12)

Country Link
US (1) US4322439A (es)
EP (1) EP0003532B1 (es)
JP (1) JPS55500064A (es)
AT (1) AT368134B (es)
CA (1) CA1133936A (es)
DE (1) DE2962600D1 (es)
ES (3) ES477421A1 (es)
GR (1) GR64803B (es)
IE (1) IE48386B1 (es)
LU (1) LU79008A1 (es)
PT (1) PT69174A (es)
WO (1) WO1979000586A1 (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3027223A1 (de) * 1980-07-18 1982-02-11 Hoechst Ag, 6000 Frankfurt Triazinylaminotriazine, ihre herstellung und verwendung
PT77219B (fr) * 1982-08-24 1986-02-04 May & Baker Ltd Procede de preparation des derives de la benzamide
US4470988A (en) * 1983-02-10 1984-09-11 Ciba-Geigy Corporation Benzazocinone and benzazoninone derivatives, and their pharmaceutical use
US4537885A (en) * 1983-02-10 1985-08-27 Ciba Geigy Corporation Certain benzazocinone and benzazoninone derivatives
NO174506B (no) * 1984-10-30 1994-02-07 Usv Pharma Corp Analogifremgangsmaate ved fremstilling av terapeutisk aktive forbindelser
EP0218728A1 (en) * 1985-04-03 1987-04-22 Yamanouchi Pharmaceutical Co. Ltd. Phenylene derivatives
US5140046A (en) * 1985-04-03 1992-08-18 Yamanouchi Pharmaceutical Co., Ltd. Phenylene derivatives, compositions and use
US5049572A (en) * 1987-04-06 1991-09-17 Riker Laboratories, Inc. Substituted di-t-butylphenols and anti-allergic use thereof
US5103037A (en) * 1987-04-06 1992-04-07 Riker Laboratories, Inc. Substituted di-t-butylphenols
US4997972A (en) * 1988-12-27 1991-03-05 Nippon Kayaku Kabushiki Kaisha 2-acylamino-5-halogenated-cinnamic acid derivative and method for its production
JP2727243B2 (ja) * 1988-12-27 1998-03-11 日本化薬株式会社 ２−アシルアミノ桂皮酸誘導体の製造法
GB9017710D0 (en) * 1990-08-13 1990-09-26 May & Baker Ltd New compositions of matter
CA2057324A1 (en) * 1990-12-18 1992-06-19 Lora Louise Fitch Benzamide and sulfonamide hypoglycemic agents

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1082466A (en) * 1965-06-29 1967-09-06 Smith & Nephew 2-benzamidophenylalkanoic acid derivatives and their preparation
US3536753A (en) * 1969-05-27 1970-10-27 Geigy Chem Corp O-(substituted benzamido)phenylacetic acids
US3636094A (en) * 1969-07-25 1972-01-18 Searle & Co Norbornanecarboxylic acid amides of anthranilic acid
US3839433A (en) * 1971-06-28 1974-10-01 Ciba Geigy Corp Adamantylcarboxamidophenylalkanoic acids and esters thereof
DE2500157C2 (de) * 1975-01-03 1983-09-15 Hoechst Ag, 6230 Frankfurt N-Acyl-4-(2-aminoäthyl)-benzoesäuren, deren Salze und Ester, Verfahren zu deren Herstellung und deren Verwendung
DK148576A (da) * 1975-04-18 1976-10-19 Boehringer Mannheim Gmbh Fenylalkankarbonsyrederivater og fremgangsmade til deres fremstilling
DE2532420A1 (de) * 1975-07-19 1977-02-03 Boehringer Mannheim Gmbh Phenylessigsaeure-derivate und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
IE48386B1 (en) 1985-01-09
DE2962600D1 (en) 1982-06-09
WO1979000586A1 (en) 1979-08-23
GR64803B (en) 1980-06-02
ES8102090A1 (es) 1981-01-16
EP0003532A1 (de) 1979-08-22
ES487989A0 (es) 1981-01-16
IE790200L (en) 1979-08-03
US4322439A (en) 1982-03-30
JPS55500064A (es) 1980-02-07
EP0003532B1 (de) 1982-04-28
ES8102089A1 (es) 1981-01-16
ATA78879A (de) 1982-01-15
ES487990A0 (es) 1981-01-16
CA1133936A (en) 1982-10-19
PT69174A (de) 1979-03-01
AT368134B (de) 1982-09-10
LU79008A1 (de) 1979-09-06

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20001009