ES476812A1 - Un procedimiento para la preparacion de derivados de la tau-rina. - Google Patents
Un procedimiento para la preparacion de derivados de la tau-rina.Info
- Publication number
- ES476812A1 ES476812A1 ES476812A ES476812A ES476812A1 ES 476812 A1 ES476812 A1 ES 476812A1 ES 476812 A ES476812 A ES 476812A ES 476812 A ES476812 A ES 476812A ES 476812 A1 ES476812 A1 ES 476812A1
- Authority
- ES
- Spain
- Prior art keywords
- taurine derivatives
- novel
- novel taurine
- derivatives
- ch2ch2or
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- XOAAWQZATWQOTB-UHFFFAOYSA-N taurine Chemical class NCCS(O)(=O)=O XOAAWQZATWQOTB-UHFFFAOYSA-N 0.000 title abstract 2
- -1 nicotinoyl Chemical group 0.000 abstract 3
- 230000010933 acylation Effects 0.000 abstract 1
- 238000005917 acylation reaction Methods 0.000 abstract 1
- 230000002402 anti-lipaemic effect Effects 0.000 abstract 1
- 230000001989 choleretic effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
- C07D213/80—Acids; Esters in position 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Un procedimiento para la preparación de derivados de la taurina de fórmula general (I) **fórmula** en la cual R y R'' representan un resto acilo del ácido nicotínico, del ácido 3,4,5- trimetoxibenzoico o del ácido acetilsalicílico, mientras que R'' puede representar, también, un resto- CH2-CH2-O-R, donde R tiene los significados anteriormente precisados, cuyo procedimiento comprende hacer reaccionar un compuesto de fórmula (II-III) **fórmula** donde W representa hidrógeno o -CH2-CH2-OH, con un derivado activo de fórmula (IV) R-X (IV) donde R tiene los significados anteriormente precisados y X representa un átomo de halógeno, un resto alcoxílico o un resto alcoxicarboniloxi.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT24587/78A IT1096662B (it) | 1978-06-15 | 1978-06-15 | Derivati taurinici ad attivita'antilipemica e coleretica,processo per la loro preparazione e composizioni farmaceutiche che li contengono |
Publications (1)
Publication Number | Publication Date |
---|---|
ES476812A1 true ES476812A1 (es) | 1979-12-16 |
Family
ID=11214073
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES476812A Expired ES476812A1 (es) | 1978-06-15 | 1979-01-12 | Un procedimiento para la preparacion de derivados de la tau-rina. |
ES482484A Expired ES482484A1 (es) | 1978-06-15 | 1979-07-13 | Un procedimiento para la preparacion de derivados de la tau-rina. |
ES482483A Expired ES482483A1 (es) | 1978-06-15 | 1979-07-13 | Un procedimiento para la preparacion de derivados de la tau-rina. |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES482484A Expired ES482484A1 (es) | 1978-06-15 | 1979-07-13 | Un procedimiento para la preparacion de derivados de la tau-rina. |
ES482483A Expired ES482483A1 (es) | 1978-06-15 | 1979-07-13 | Un procedimiento para la preparacion de derivados de la tau-rina. |
Country Status (9)
Country | Link |
---|---|
JP (2) | JPS5943942B2 (es) |
BE (1) | BE876969A (es) |
DE (1) | DE2901046C3 (es) |
ES (3) | ES476812A1 (es) |
FR (2) | FR2465717A1 (es) |
GB (1) | GB2023586B (es) |
IT (1) | IT1096662B (es) |
LU (1) | LU81379A1 (es) |
NL (1) | NL7904644A (es) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1126575B (it) * | 1979-12-07 | 1986-05-21 | Causyth Chim Farm | Composto ad attivita' antiinfiammatoria,analgesica e antipiretica,processo per la sua preparazione,e relative composizioni farmaceutiche |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB586453A (en) * | 1944-08-01 | 1947-03-19 | Ward Blenkinsop & Co Ltd | Process for the production of derivatives of nicotinic acid |
FR920312A (fr) * | 1944-08-01 | 1947-04-03 | Ward | Procédé de préparation de dérivés de l'acide nicotique |
CH520697A (fr) * | 1970-03-03 | 1972-03-31 | Sopharma Sa | Procédé de préparation d'un ester-amide de l'acide nicotinique |
-
1978
- 1978-06-15 IT IT24587/78A patent/IT1096662B/it active
-
1979
- 1979-01-11 FR FR7900641A patent/FR2465717A1/fr active Pending
- 1979-01-12 ES ES476812A patent/ES476812A1/es not_active Expired
- 1979-01-12 DE DE2901046A patent/DE2901046C3/de not_active Expired
- 1979-06-13 NL NL7904644A patent/NL7904644A/xx not_active Application Discontinuation
- 1979-06-13 JP JP54075148A patent/JPS5943942B2/ja not_active Expired
- 1979-06-14 LU LU81379A patent/LU81379A1/xx unknown
- 1979-06-14 BE BE2/57867A patent/BE876969A/xx not_active IP Right Cessation
- 1979-06-15 GB GB7920953A patent/GB2023586B/en not_active Expired
- 1979-07-13 ES ES482484A patent/ES482484A1/es not_active Expired
- 1979-07-13 ES ES482483A patent/ES482483A1/es not_active Expired
-
1982
- 1982-08-11 FR FR8214014A patent/FR2511365A1/fr active Granted
-
1983
- 1983-12-16 JP JP23774083A patent/JPS6133171A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
GB2023586B (en) | 1982-08-04 |
ES482484A1 (es) | 1980-04-01 |
JPS5943942B2 (ja) | 1984-10-25 |
DE2901046C3 (de) | 1982-05-06 |
DE2901046B2 (de) | 1981-07-16 |
LU81379A1 (fr) | 1979-09-12 |
NL7904644A (nl) | 1979-12-18 |
FR2511365B1 (es) | 1985-03-15 |
ES482483A1 (es) | 1980-04-16 |
IT7824587A0 (it) | 1978-06-15 |
FR2465717A1 (fr) | 1981-03-27 |
FR2511365A1 (fr) | 1983-02-18 |
JPS554381A (en) | 1980-01-12 |
GB2023586A (en) | 1980-01-03 |
BE876969A (nl) | 1979-10-01 |
IT1096662B (it) | 1985-08-26 |
JPS6133171A (ja) | 1986-02-17 |
DE2901046A1 (de) | 1979-12-20 |
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