ES475100A1 - Un metodo para preparar acidos 1,2-benzisoxazoloxiaceticos - Google Patents
Un metodo para preparar acidos 1,2-benzisoxazoloxiaceticosInfo
- Publication number
- ES475100A1 ES475100A1 ES475100A ES475100A ES475100A1 ES 475100 A1 ES475100 A1 ES 475100A1 ES 475100 A ES475100 A ES 475100A ES 475100 A ES475100 A ES 475100A ES 475100 A1 ES475100 A1 ES 475100A1
- Authority
- ES
- Spain
- Prior art keywords
- alkyl
- hydrogen
- benzisoxazolyloxy
- thio
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/30—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
- C07C45/46—Friedel-Crafts reactions
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/673—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C47/00—Compounds having —CHO groups
- C07C47/52—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
- C07C47/575—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/82—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups
- C07C49/83—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups polycyclic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/84—Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/76—Unsaturated compounds containing keto groups
- C07C59/90—Unsaturated compounds containing keto groups containing singly bound oxygen-containing groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
- C07D213/46—Oxygen atoms
- C07D213/50—Ketonic radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
- C07D213/53—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/20—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
- C07D275/04—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/40—Radicals substituted by oxygen atoms
- C07D307/46—Doubly bound oxygen atoms, or two oxygen atoms singly bound to the same carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/22—Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom
Abstract
Nuevos ácidos 1,2-benzisoxazoloxiacéticos y compuestos relacionados que son útiles como diuréticos, uricosúricos e hipertensores a métodos para su preparación y a composiciones a métodos para su preparación y a composiciones farmacéuticas que contienen tales compuestos como ingrediente activo.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US85331377A | 1977-11-21 | 1977-11-21 | |
US94912878A | 1978-10-06 | 1978-10-06 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES475100A1 true ES475100A1 (es) | 1979-12-01 |
Family
ID=27127134
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES475100A Expired ES475100A1 (es) | 1977-11-21 | 1978-11-15 | Un metodo para preparar acidos 1,2-benzisoxazoloxiaceticos |
ES482056A Expired ES482056A1 (es) | 1977-11-21 | 1979-06-29 | Un metodo par preparar acidos 1,2-benzisocazoloxiaceticos. |
ES482055A Expired ES482055A1 (es) | 1977-11-21 | 1979-06-29 | Un metodo para preparar acidos 1,2-benzisoxazoloxiaceticos. |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES482056A Expired ES482056A1 (es) | 1977-11-21 | 1979-06-29 | Un metodo par preparar acidos 1,2-benzisocazoloxiaceticos. |
ES482055A Expired ES482055A1 (es) | 1977-11-21 | 1979-06-29 | Un metodo para preparar acidos 1,2-benzisoxazoloxiaceticos. |
Country Status (18)
Country | Link |
---|---|
EP (1) | EP0002666B1 (es) |
JP (1) | JPS5495563A (es) |
AT (1) | AT371811B (es) |
AU (1) | AU521533B2 (es) |
CA (1) | CA1111853A (es) |
DE (1) | DE2861637D1 (es) |
DK (1) | DK515978A (es) |
EG (1) | EG13533A (es) |
ES (3) | ES475100A1 (es) |
FI (1) | FI783515A (es) |
GR (1) | GR72950B (es) |
HU (1) | HU180785B (es) |
IE (1) | IE47299B1 (es) |
IL (1) | IL55997A0 (es) |
IT (1) | IT7829897A0 (es) |
NO (1) | NO783908L (es) |
NZ (1) | NZ188946A (es) |
PT (1) | PT68807A (es) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4337261A (en) * | 1980-07-28 | 1982-06-29 | Hoechst-Roussel Pharmaceuticals Inc. | (1,2-Benzisoxazol)phenoxyacetic acids as diuretics |
US4452804A (en) * | 1981-02-25 | 1984-06-05 | Hoechst-Roussel Pharmaceuticals Inc. | 1,2-Benzisoxazoloxyethylamines and intermediates for the preparation thereof |
US4644064A (en) * | 1981-02-25 | 1987-02-17 | Hoechst-Roussel Pharmaceuticals Inc. | 1,2-benzisoxazoloxyethylamines and intermediates for the preparation thereof |
US4504669A (en) * | 1981-02-25 | 1985-03-12 | Hoechst-Roussel Pharmaceuticals Inc. | 1,2-Benzisoxazoloxyethylamines and intermediates for the preparation thereof |
US4427691A (en) * | 1981-02-25 | 1984-01-24 | Hoechst-Roussel Pharmaceuticals Inc. | 1,2-Benzisoxazoloxyethylamines and intermediates for the preparation thereof |
JPS59128347A (ja) * | 1983-01-12 | 1984-07-24 | Daikin Ind Ltd | 含フツ素ベンゾフエノン誘導体 |
US4458076A (en) * | 1983-05-31 | 1984-07-03 | Hoechst-Roussel Pharmaceuticals | 3-(4-Piperidinyl)-1,2-benzisothiazoles |
GB9620202D0 (en) * | 1996-09-27 | 1996-11-13 | Rhone Poulenc Agriculture | New herbicides |
TW200637839A (en) | 2005-01-07 | 2006-11-01 | Taisho Pharmaceutical Co Ltd | 1-thio-d-glucitol derivatives |
WO2008035359A2 (en) * | 2006-06-12 | 2008-03-27 | Cadila Healthcare Limited | Oximinophenoxyalkanoic acid and phenylalkanoic acid derivatives |
AR081930A1 (es) * | 2010-06-16 | 2012-10-31 | Ardea Biosciences Inc | Compuestos de tioacetato |
-
1978
- 1978-11-15 ES ES475100A patent/ES475100A1/es not_active Expired
- 1978-11-17 FI FI783515A patent/FI783515A/fi not_active Application Discontinuation
- 1978-11-17 IT IT7829897A patent/IT7829897A0/it unknown
- 1978-11-20 DK DK515978A patent/DK515978A/da not_active Application Discontinuation
- 1978-11-20 PT PT68807A patent/PT68807A/pt unknown
- 1978-11-20 HU HU78HO2116A patent/HU180785B/hu unknown
- 1978-11-20 DE DE7878101409T patent/DE2861637D1/de not_active Expired
- 1978-11-20 AT AT0824478A patent/AT371811B/de not_active IP Right Cessation
- 1978-11-20 CA CA316,532A patent/CA1111853A/en not_active Expired
- 1978-11-20 EP EP78101409A patent/EP0002666B1/de not_active Expired
- 1978-11-20 AU AU41716/78A patent/AU521533B2/en not_active Expired
- 1978-11-20 NZ NZ188946A patent/NZ188946A/xx unknown
- 1978-11-20 IE IE2275/78A patent/IE47299B1/en unknown
- 1978-11-20 NO NO783908A patent/NO783908L/no unknown
- 1978-11-20 IL IL55997A patent/IL55997A0/xx unknown
- 1978-11-21 JP JP14402578A patent/JPS5495563A/ja active Pending
- 1978-11-21 EG EG662/78A patent/EG13533A/xx active
- 1978-11-21 GR GR57693A patent/GR72950B/el unknown
-
1979
- 1979-06-29 ES ES482056A patent/ES482056A1/es not_active Expired
- 1979-06-29 ES ES482055A patent/ES482055A1/es not_active Expired
Also Published As
Publication number | Publication date |
---|---|
IL55997A0 (en) | 1979-01-31 |
ES482055A1 (es) | 1980-09-01 |
IE47299B1 (en) | 1984-02-08 |
NZ188946A (en) | 1983-05-10 |
AU4171678A (en) | 1979-05-31 |
PT68807A (en) | 1978-12-01 |
HU180785B (en) | 1983-04-29 |
IE782275L (en) | 1979-05-21 |
EG13533A (en) | 1981-12-31 |
IT7829897A0 (it) | 1978-11-17 |
AT371811B (de) | 1983-08-10 |
GR72950B (es) | 1984-01-17 |
ATA824478A (de) | 1982-12-15 |
AU521533B2 (en) | 1982-04-08 |
JPS5495563A (en) | 1979-07-28 |
CA1111853A (en) | 1981-11-03 |
FI783515A (fi) | 1979-05-22 |
EP0002666B1 (de) | 1982-02-17 |
EP0002666A1 (de) | 1979-07-11 |
DK515978A (da) | 1979-05-22 |
NO783908L (no) | 1979-05-22 |
ES482056A1 (es) | 1980-09-01 |
DE2861637D1 (en) | 1982-03-25 |
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