ES469878A1 - Un procedimiento para preparar una composicion farmaceutica para el tratamiento del habito de consumir drogas - Google Patents
Un procedimiento para preparar una composicion farmaceutica para el tratamiento del habito de consumir drogasInfo
- Publication number
- ES469878A1 ES469878A1 ES469878A ES469878A ES469878A1 ES 469878 A1 ES469878 A1 ES 469878A1 ES 469878 A ES469878 A ES 469878A ES 469878 A ES469878 A ES 469878A ES 469878 A1 ES469878 A1 ES 469878A1
- Authority
- ES
- Spain
- Prior art keywords
- tyrosine
- alpha
- methyl
- para
- drug addiction
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- NHTGHBARYWONDQ-JTQLQIEISA-N L-α-methyl-Tyrosine Chemical compound OC(=O)[C@](N)(C)CC1=CC=C(O)C=C1 NHTGHBARYWONDQ-JTQLQIEISA-N 0.000 title abstract 2
- 206010013663 drug dependence Diseases 0.000 title 1
- 208000011117 substance-related disease Diseases 0.000 title 1
- 206010011509 Crystalluria Diseases 0.000 abstract 1
- 230000003113 alkalizing effect Effects 0.000 abstract 1
- 239000002775 capsule Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 238000002347 injection Methods 0.000 abstract 1
- 239000007924 injection Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000006187 pill Substances 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
- 210000002700 urine Anatomy 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Un procedimiento para preparar una composición farmacéutica para el tratamiento del hábito de consumir drogas sin experimentar cristaluria, que comprende asociar una cantidad predeterminada terapéuticamente eficaz de alfa-metil-tirosina de la fórmula estructural **(Fórmula)** Y un agente alcalinizante en una cantidad suficiente para que, a la dosis administrada, provoque que la orina del paciente tenga un pH alcalino, preferiblemente superior a 7,4 y seguidamente llevar la composición obtenida a una forma de administración adecuada, tal como píldora, cápsula, solución para inyección y otras.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/797,372 US4117161A (en) | 1977-05-16 | 1977-05-16 | Method of pharmacologically treating drug addiction with alpha-methyl-para-tyrosine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES469878A1 true ES469878A1 (es) | 1979-09-16 |
Family
ID=25170655
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES469878A Expired ES469878A1 (es) | 1977-05-16 | 1978-05-16 | Un procedimiento para preparar una composicion farmaceutica para el tratamiento del habito de consumir drogas |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US4117161A (es) |
| JP (1) | JPS53142535A (es) |
| CA (1) | CA1091155A (es) |
| ES (1) | ES469878A1 (es) |
| IT (1) | IT1104177B (es) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5051426A (en) * | 1990-03-27 | 1991-09-24 | Parnell Pharmaceuticals, Inc. | Method for effecting withdrawal from drug dependency |
| US5219858A (en) * | 1990-03-27 | 1993-06-15 | Parnell Pharmaceuticals, Inc. | Method and compositions for effecting withdrawal from drug dependency |
| US20040167164A1 (en) * | 1998-05-05 | 2004-08-26 | Jose Pozuelo | Compositions and methods for treating particular chemical addictions and mental illnesses |
| US20030049272A1 (en) * | 2001-08-30 | 2003-03-13 | Yatindra Joshi | Pharmaceutical composition which produces irritation |
| RU2209062C1 (ru) * | 2002-03-19 | 2003-07-27 | Институт физиологии им. И.П.Павлова РАН | Вещество, обладающее седативным действием |
| US20130183263A1 (en) | 2012-01-17 | 2013-07-18 | Steven Hoffman | Pharmaceutical compositions and methods |
| US8481498B1 (en) | 2012-01-17 | 2013-07-09 | Steven Hoffman | Pharmaceutical compositions and methods |
| US10272068B2 (en) | 2012-01-17 | 2019-04-30 | Tyme, Inc. | Pharmaceutical compositions and methods |
| US10646552B2 (en) | 2012-01-17 | 2020-05-12 | Tyme, Inc. | Pharmaceutical compositions and methods |
| US10751313B2 (en) | 2013-10-22 | 2020-08-25 | Yamo Pharmaceuticals Llc | Compositions and methods for treating autism |
| US9326962B2 (en) | 2013-10-22 | 2016-05-03 | Steven Hoffman | Compositions and methods for treating intestinal hyperpermeability |
| US9763903B2 (en) | 2013-10-22 | 2017-09-19 | Steven Hoffman | Compositions and methods for treating intestinal hyperpermeability |
| US9585841B2 (en) | 2013-10-22 | 2017-03-07 | Tyme, Inc. | Tyrosine derivatives and compositions comprising them |
| US10813901B2 (en) | 2013-10-22 | 2020-10-27 | Yamo Pharmaceuticals Llc | Compositions and methods for treating autism |
| EP3749290A4 (en) | 2018-01-29 | 2022-01-26 | Jonathan Sackner-Bernstein | METHODS OF DOPAMINE MODULATION IN HUMAN NEUROLOGICAL DISEASES |
| AU2019306092A1 (en) | 2018-07-19 | 2021-02-04 | Yamo Pharmaceuticals Llc | Compositions and methods for treating autism |
| RU2719575C1 (ru) * | 2019-02-01 | 2020-04-21 | Общество с ограниченной ответственностью "Центр ранней диагностики нейродегенеративных заболеваний (НДЗ)" | Фармацевтическая композиция на основе альфа-метил-п-тирозина и способ ранней диагностики болезни Паркинсона |
| EP3968785A4 (en) | 2019-05-14 | 2023-01-11 | Tyme, Inc. | COMPOSITIONS AND METHODS FOR TREATMENT OF CANCER |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3787581A (en) * | 1970-03-24 | 1974-01-22 | M Sandler | Pharmaceutical compositions and methods of treatment |
-
1977
- 1977-05-16 US US05/797,372 patent/US4117161A/en not_active Expired - Lifetime
-
1978
- 1978-05-11 CA CA303,280A patent/CA1091155A/en not_active Expired
- 1978-05-15 IT IT49358/78A patent/IT1104177B/it active
- 1978-05-16 JP JP5816078A patent/JPS53142535A/ja active Pending
- 1978-05-16 ES ES469878A patent/ES469878A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| IT7849358A0 (it) | 1978-05-15 |
| US4117161A (en) | 1978-09-26 |
| JPS53142535A (en) | 1978-12-12 |
| CA1091155A (en) | 1980-12-09 |
| IT1104177B (it) | 1985-10-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19980302 |