ES469554A1 - Process for prepartng imidazolidinylideneebenzamine - Google Patents

Process for prepartng imidazolidinylideneebenzamine

Info

Publication number
ES469554A1
ES469554A1 ES469554A ES469554A ES469554A1 ES 469554 A1 ES469554 A1 ES 469554A1 ES 469554 A ES469554 A ES 469554A ES 469554 A ES469554 A ES 469554A ES 469554 A1 ES469554 A1 ES 469554A1
Authority
ES
Spain
Prior art keywords
prepartng
imidazolidinylideneebenzamine
bromo
acid
addition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES469554A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CH Boehringer Sohn AG and Co KG
Original Assignee
CH Boehringer Sohn AG and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CH Boehringer Sohn AG and Co KG filed Critical CH Boehringer Sohn AG and Co KG
Publication of ES469554A1 publication Critical patent/ES469554A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/44—Nitrogen atoms not forming part of a nitro radical
    • C07D233/50—Nitrogen atoms not forming part of a nitro radical with carbocyclic radicals directly attached to said nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • C07D473/08—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1 and 3, e.g. theophylline

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Catalysts (AREA)

Abstract

Process for the preparation of 2-bromo-3-chloro-N-2-imidazolidinylidene-benzamine and its addition salts, of acid, characterized in that the 2-bromo-3-chloroaniline is reacted with ethyleneurea in the presence of phosphorus oxychloride and eventually the compound obtained is transformed into a salt by the addition of acid. (Machine-translation by Google Translate, not legally binding)
ES469554A 1976-12-24 1978-05-08 Process for prepartng imidazolidinylideneebenzamine Expired ES469554A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19762658808 DE2658808A1 (en) 1976-12-24 1976-12-24 2-BROMINE-3-CHLORINE-N-2-IMIDAZOLIDINYLENE-BENZAMINE, ITS ACID ADDITION SALTS, MEDICINAL PRODUCTS CONTAINING THEM AND METHOD FOR THE PRODUCTION THEREOF

Publications (1)

Publication Number Publication Date
ES469554A1 true ES469554A1 (en) 1978-12-01

Family

ID=5996607

Family Applications (6)

Application Number Title Priority Date Filing Date
ES465368A Expired ES465368A1 (en) 1976-12-24 1977-12-23 Process for prepartng imidazolidinylideneebenzamine
ES469555A Expired ES469555A1 (en) 1976-12-24 1978-05-08 Process for prepartng imidazolidinylideneebenzamine
ES469554A Expired ES469554A1 (en) 1976-12-24 1978-05-08 Process for prepartng imidazolidinylideneebenzamine
ES469552A Expired ES469552A1 (en) 1976-12-24 1978-05-08 Process for prepartng imidazolidinylideneebenzamine
ES469553A Expired ES469553A1 (en) 1976-12-24 1978-05-08 Process for prepartng imidazolidinylideneebenzamine
ES469551A Expired ES469551A1 (en) 1976-12-24 1978-05-08 Process for prepartng imidazolidinylideneebenzamine

Family Applications Before (2)

Application Number Title Priority Date Filing Date
ES465368A Expired ES465368A1 (en) 1976-12-24 1977-12-23 Process for prepartng imidazolidinylideneebenzamine
ES469555A Expired ES469555A1 (en) 1976-12-24 1978-05-08 Process for prepartng imidazolidinylideneebenzamine

Family Applications After (3)

Application Number Title Priority Date Filing Date
ES469552A Expired ES469552A1 (en) 1976-12-24 1978-05-08 Process for prepartng imidazolidinylideneebenzamine
ES469553A Expired ES469553A1 (en) 1976-12-24 1978-05-08 Process for prepartng imidazolidinylideneebenzamine
ES469551A Expired ES469551A1 (en) 1976-12-24 1978-05-08 Process for prepartng imidazolidinylideneebenzamine

Country Status (19)

Country Link
JP (1) JPS5379867A (en)
AU (1) AU3187277A (en)
BE (1) BE862305A (en)
BG (1) BG28575A3 (en)
DD (1) DD133944A5 (en)
DE (1) DE2658808A1 (en)
DK (1) DK577777A (en)
ES (6) ES465368A1 (en)
FI (1) FI773559A (en)
FR (1) FR2375217A1 (en)
GR (1) GR65962B (en)
IL (1) IL53681A0 (en)
LU (1) LU78757A1 (en)
NL (1) NL7714352A (en)
NO (1) NO774445L (en)
PT (1) PT67448A (en)
SE (1) SE7714750L (en)
SU (1) SU679139A3 (en)
ZA (1) ZA777198B (en)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1545628A1 (en) * 1965-10-01 1970-06-25 Boehringer Sohn Ingelheim Process for the preparation of antihypertensive and sedative derivatives of 2- (2-haloanilino) -1,3-diazacyclopentene- (2)
BE787683A (en) * 1971-08-20 1973-02-19 Boehringer Sohn Ingelheim 2-PHENYLIMINO-IMIDAZOLIDINES, THEIR ADDITIONAL SALTS WITH ACIDS AND METHODS FOR MAKING THEM
AT330769B (en) * 1974-04-05 1976-07-26 Chemie Linz Ag PROCESS FOR THE PRODUCTION OF 2-ARYLAMINO-2-IMIDAZOLINE DERIVATIVES AND THEIR SALT

Also Published As

Publication number Publication date
DE2658808A1 (en) 1978-07-06
JPS5379867A (en) 1978-07-14
SU679139A3 (en) 1979-08-05
NO774445L (en) 1978-06-27
PT67448A (en) 1978-01-01
ZA777198B (en) 1979-08-29
ES469553A1 (en) 1978-12-01
BG28575A3 (en) 1980-05-15
NL7714352A (en) 1978-06-27
IL53681A0 (en) 1978-03-10
FR2375217A1 (en) 1978-07-21
BE862305A (en) 1978-06-23
ES469555A1 (en) 1978-12-01
AU3187277A (en) 1979-06-28
ES465368A1 (en) 1978-09-16
ES469552A1 (en) 1978-12-01
FI773559A (en) 1978-06-25
DK577777A (en) 1978-06-25
DD133944A5 (en) 1979-01-31
ES469551A1 (en) 1978-12-01
GR65962B (en) 1981-01-09
SE7714750L (en) 1978-06-25
LU78757A1 (en) 1979-02-02

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