ES469496A1 - Procedimiento para preparar acidos y esteres 2-ariloxi-2-( para-fenoxialcoxi)fenilaceticos sustituidos - Google Patents
Procedimiento para preparar acidos y esteres 2-ariloxi-2-( para-fenoxialcoxi)fenilaceticos sustituidosInfo
- Publication number
- ES469496A1 ES469496A1 ES469496A ES469496A ES469496A1 ES 469496 A1 ES469496 A1 ES 469496A1 ES 469496 A ES469496 A ES 469496A ES 469496 A ES469496 A ES 469496A ES 469496 A1 ES469496 A1 ES 469496A1
- Authority
- ES
- Spain
- Prior art keywords
- phenoxyalkoxy
- aryloxy
- esters
- acetic acid
- phenyl acetic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
- C07C309/63—Esters of sulfonic acids
- C07C309/64—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms
- C07C309/65—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms of a saturated carbon skeleton
- C07C309/66—Methanesulfonates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Nuevas composiciones de materia que contienen compuestos útiles como agentes hipolipidémicos, así como el método para rebajar esterol del suero. Se ha dedicado un esfuerzo considerable en los últimos años para obtener sustancias que sean de utilidad en el tratamiento de la hiperlipidemia, un estado asociado con elevados niveles en la sangre de colesterol, fosfolípidos y/o triglicéridos. Este estado viene asociado con diversas enfermedades, siendo una de las más serias la aterosclerosis. Los medicamentos usados para rebajar los niveles en sangre de colesterol, fosfolípidos y triglicéridos se denominan productos hipolipidémicos. En la actualidad se dispone de tres agentes principales disminuidores del nivel de lípidos, a saber clofibrato, D-tiroxina, y ácido nicotínico.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US05/794,510 US4125732A (en) | 1977-05-06 | 1977-05-06 | 2-Aryloxy-2-(phenoxyalkoxy)phenyl acetic acid and esters |
Publications (1)
Publication Number | Publication Date |
---|---|
ES469496A1 true ES469496A1 (es) | 1979-09-16 |
Family
ID=25162842
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES469496A Expired ES469496A1 (es) | 1977-05-06 | 1978-05-05 | Procedimiento para preparar acidos y esteres 2-ariloxi-2-( para-fenoxialcoxi)fenilaceticos sustituidos |
ES471826A Expired ES471826A1 (es) | 1977-05-06 | 1978-07-18 | Procedimiento para preparar acidos y esteres 2-ariloxi-2- (parafenoxialcoxi)fenilaceticossustituidos. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES471826A Expired ES471826A1 (es) | 1977-05-06 | 1978-07-18 | Procedimiento para preparar acidos y esteres 2-ariloxi-2- (parafenoxialcoxi)fenilaceticossustituidos. |
Country Status (18)
Country | Link |
---|---|
US (1) | US4125732A (es) |
JP (1) | JPS53137928A (es) |
AU (1) | AU3515778A (es) |
BE (1) | BE866721A (es) |
CU (1) | CU34914A (es) |
DD (1) | DD136134A5 (es) |
DE (1) | DE2819263A1 (es) |
DK (1) | DK197878A (es) |
ES (2) | ES469496A1 (es) |
FI (1) | FI781298A (es) |
FR (1) | FR2389594B1 (es) |
IL (1) | IL54488A0 (es) |
IT (1) | IT1105289B (es) |
NL (1) | NL7804504A (es) |
PL (1) | PL206611A1 (es) |
PT (1) | PT68000B (es) |
SE (1) | SE7805185L (es) |
ZA (1) | ZA782041B (es) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1201127A (en) * | 1982-09-10 | 1986-02-25 | Katsuhiro Uchida | Biphenylylpropionic acid derivative, process for preparing the same and pharmaceutical composition containing the same |
US4983628A (en) * | 1983-10-27 | 1991-01-08 | Merck Frosst Canada, Inc. | Leukotriene antagonists |
US4683325A (en) * | 1984-01-23 | 1987-07-28 | Merck Frosst Canada, Inc. | Leukotriene antagonists |
WO1986007353A1 (en) * | 1985-06-14 | 1986-12-18 | Pfizer Inc. | Intermediate in the production of an asymmetric hydantoin |
WO2002009651A2 (en) * | 2000-08-02 | 2002-02-07 | Smithkline Beecham Corporation | Fatty acid synthase inhibitors |
JP2004521124A (ja) * | 2001-02-09 | 2004-07-15 | メルク エンド カムパニー インコーポレーテッド | 糖尿病および脂質障害用の2−アリールオキシ−2−アリールアルカン酸類 |
DE602004028500D1 (de) * | 2003-09-19 | 2010-09-16 | Janssen Pharmaceutica Nv | 4-((phenoxyalkyl)thio)-phenoxyessigsäuren und analoga |
SI1667964T1 (sl) | 2003-09-19 | 2009-12-31 | Janssen Pharmaceutica Nv | 4-((fenoksialkil)tio)-fenoksiocetne kisline in analogi |
MY147518A (en) * | 2004-09-15 | 2012-12-31 | Janssen Pharmaceutica Nv | 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs |
MY145712A (en) * | 2004-09-15 | 2012-03-30 | Janssen Pharmaceutica Nv | 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs |
US7161026B1 (en) | 2005-07-08 | 2007-01-09 | Property Development Corporation International, Ltd, Inc. | Method of preparation of methyl-benzyl-ketone |
JO3006B1 (ar) * | 2005-09-14 | 2016-09-05 | Janssen Pharmaceutica Nv | املاح ليسين مبتكرة من مشتقات حامض 4-((فينوكسي الكيل)ثيو) فينوكسي الخليك |
UY30288A1 (es) * | 2006-04-18 | 2007-08-31 | Janssen Pharmaceutica Nv | Derivados del ácido benzoazepin-oxi-acético como agonistas de ppar-delta usados para aumentar hdl-c. reducir ldl-c y reducir colesterol |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA755105A (en) * | 1967-03-21 | A. Bolhofer William | Alpha-phenoxy and alpha-phenylthio carboxylic acids |
-
1977
- 1977-05-06 US US05/794,510 patent/US4125732A/en not_active Expired - Lifetime
-
1978
- 1978-04-10 ZA ZA00782041A patent/ZA782041B/xx unknown
- 1978-04-12 IL IL54488A patent/IL54488A0/xx unknown
- 1978-04-17 AU AU35157/78A patent/AU3515778A/en active Pending
- 1978-04-26 FI FI781298A patent/FI781298A/fi not_active Application Discontinuation
- 1978-04-26 NL NL7804504A patent/NL7804504A/xx not_active Application Discontinuation
- 1978-05-02 DE DE19782819263 patent/DE2819263A1/de not_active Withdrawn
- 1978-05-04 IT IT49200/78A patent/IT1105289B/it active
- 1978-05-05 DD DD78205215A patent/DD136134A5/xx unknown
- 1978-05-05 PL PL20661178A patent/PL206611A1/xx unknown
- 1978-05-05 ES ES469496A patent/ES469496A1/es not_active Expired
- 1978-05-05 FR FR7813417A patent/FR2389594B1/fr not_active Expired
- 1978-05-05 SE SE7805185A patent/SE7805185L/xx unknown
- 1978-05-05 DK DK197878A patent/DK197878A/da unknown
- 1978-05-05 BE BE187405A patent/BE866721A/xx unknown
- 1978-05-05 PT PT68000A patent/PT68000B/pt unknown
- 1978-05-06 CU CU7834914A patent/CU34914A/es unknown
- 1978-05-06 JP JP5399878A patent/JPS53137928A/ja active Pending
- 1978-07-18 ES ES471826A patent/ES471826A1/es not_active Expired
Also Published As
Publication number | Publication date |
---|---|
DK197878A (da) | 1978-11-07 |
PT68000B (en) | 1979-10-22 |
PL206611A1 (pl) | 1979-12-17 |
DD136134A5 (de) | 1979-06-20 |
IT1105289B (it) | 1985-10-28 |
CU34914A (es) | 1980-10-30 |
SE7805185L (sv) | 1978-11-07 |
FR2389594A1 (es) | 1978-12-01 |
IT7849200A0 (it) | 1978-05-04 |
AU3515778A (en) | 1979-10-25 |
US4125732A (en) | 1978-11-14 |
FI781298A (fi) | 1978-11-07 |
PT68000A (en) | 1978-06-01 |
IL54488A0 (en) | 1978-07-31 |
ZA782041B (en) | 1979-03-28 |
JPS53137928A (en) | 1978-12-01 |
FR2389594B1 (es) | 1980-10-31 |
NL7804504A (nl) | 1978-11-08 |
ES471826A1 (es) | 1979-10-16 |
BE866721A (fr) | 1978-11-06 |
DE2819263A1 (de) | 1978-11-16 |
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