ES468208A1 - Un procedimiento para la preparacion de un 1-aminoindano - Google Patents

Un procedimiento para la preparacion de un 1-aminoindano

Info

Publication number
ES468208A1
ES468208A1 ES468208A ES468208A ES468208A1 ES 468208 A1 ES468208 A1 ES 468208A1 ES 468208 A ES468208 A ES 468208A ES 468208 A ES468208 A ES 468208A ES 468208 A1 ES468208 A1 ES 468208A1
Authority
ES
Spain
Prior art keywords
aminoindane
chlorinated
methyl transferase
transferase inhibitors
inhibitors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES468208A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of ES468208A1 publication Critical patent/ES468208A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/353—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by isomerisation; by change of size of the carbon skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Un Procedimiento para la preparación de un 1-aminoindano de fórmula: **(Fórmula)** donde R es cloro o trifluormetilo y n es 1 o 2, con la condición de que n es l cuando R es trifluormetilo y además, con la condición de que, cuando R es cloro y n es l, el átomo de cloro se encuentra en la posición 4 y cuando R es cloro y n es 2, los átomos de cloro son adyacentes entre sí; y sus sales farmacéuticamente aceptable.
ES468208A 1977-03-28 1978-03-22 Un procedimiento para la preparacion de un 1-aminoindano Expired ES468208A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/782,280 US4096173A (en) 1977-03-28 1977-03-28 Chlorinated 1-aminoindane N-methyl transferase inhibitors

Publications (1)

Publication Number Publication Date
ES468208A1 true ES468208A1 (es) 1979-09-16

Family

ID=25125567

Family Applications (1)

Application Number Title Priority Date Filing Date
ES468208A Expired ES468208A1 (es) 1977-03-28 1978-03-22 Un procedimiento para la preparacion de un 1-aminoindano

Country Status (9)

Country Link
US (1) US4096173A (es)
JP (1) JPS53130644A (es)
BE (1) BE865165A (es)
DE (1) DE2812578A1 (es)
ES (1) ES468208A1 (es)
FR (1) FR2385682A1 (es)
GB (1) GB1596248A (es)
IL (1) IL54337A (es)
NL (1) NL7803162A (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4128666A (en) * 1977-08-18 1978-12-05 Smithkline Corporation 4 AND 5-Halo substituted 2-indanamine compounds
US4320148A (en) * 1980-11-24 1982-03-16 Smithkline Corporation 2-Aminotetralin compounds, pharmaceutical compositions and method of producing central alpha1 agonist activity
JPS62178552A (ja) * 1986-02-03 1987-08-05 Taiyo Yakuhin Kogyo Kk インデン類化合物
US4808754A (en) * 1987-02-27 1989-02-28 General Electric Company Spirobiindane bis-aminophenoxy ethers
CA2180841C (en) * 1994-01-10 2007-03-27 Sasson Cohen 1-aminoindan derivatives and compositions thereof
US5914349A (en) * 1994-01-10 1999-06-22 Teva Pharmaceutical Industries, Ltd. Compositions containing and methods of using 1-aminoindan and derivatives thereof and process for preparing optically active 1-aminoindan derivatives
DE69738275T2 (de) 1996-12-18 2008-08-28 Teva Pharmaceutical Industries Ltd. Aminoindanderivate
AU8031598A (en) * 1997-06-05 1998-12-21 Venantius Limited 3-aminoindane derivatives, process for their preparation and pharmaceutical compositions containing them
US6737547B1 (en) 1998-12-31 2004-05-18 Teva Pharmaceutical Industries, Ltd. Compositions containing and methods of using N-acyl-1H-aminoindenes
WO2001030339A1 (en) * 1999-10-27 2001-05-03 Teva Pharmaceutical Industries, Ltd. Use of 1-aminoindan derivatives for treatment of mania in bipolar mood disorder
US20040010038A1 (en) * 2002-02-27 2004-01-15 Eran Blaugrund Propargylamino indan derivatives and propargylamino tetralin derivatives as brain-selective MAO inhibitors
CA2515116C (en) * 2003-02-05 2014-01-21 Bayer Cropscience Gmbh Amino-1,3,5-triazines n-substituted with chiral bicyclic radicals, process for their preparation, compositions thereof, and their use as herbicides and plant growth regulators
BRPI0620659A2 (pt) * 2005-12-09 2017-10-31 Yissum Res Dev Co Of Hebrew Univ Jerusalem Ltd método para a prevenção do aparecimento de sintomas de uma doença neurodegenerativa em um indivíduo predisposto à doença neurodegenerativa, método de redução de stress oxidante no cérebro de um indivíduo afligido com stress oxidante, método de tratamento de um indivíduo afligido com a degeneração cognitiva suave e composição farmacêutica
US20070135518A1 (en) * 2005-12-09 2007-06-14 Marta Weinstock-Rosin Use of low-dose ladostigil for neuroprotection
TW200744576A (en) * 2006-02-24 2007-12-16 Teva Pharma Propargylated aminoindans, processes for preparation, and uses thereof
US7598417B2 (en) 2007-04-12 2009-10-06 Allergan, Inc. Substituted fluoroethyl ureas as alpha 2 adrenergic agents
CN105980381A (zh) 2013-11-08 2016-09-28 拜耳医药股份有限公司 取代的尿嘧啶及其用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3060091A (en) * 1961-02-13 1962-10-23 Ciba Geigy Corp Analgesic composition consisting of morphines and amino-indanes
GB1187017A (en) * 1966-07-16 1970-04-08 Aspro Nicholas Ltd Substituted 1-Amino Indanes and Tetrahydronaphthalens
US3637740A (en) * 1969-04-21 1972-01-25 Pfizer Aminobenzocycloalkane compounds
US3919316A (en) * 1974-08-05 1975-11-11 Lilly Co Eli 2-Aminodichlorotetralins

Also Published As

Publication number Publication date
DE2812578A1 (de) 1978-10-05
BE865165A (fr) 1978-09-22
GB1596248A (en) 1981-08-19
US4096173A (en) 1978-06-20
NL7803162A (nl) 1978-10-02
IL54337A (en) 1980-12-31
JPS53130644A (en) 1978-11-14
FR2385682A1 (fr) 1978-10-27

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