ES466993A1 - Procedimiento de preparacion de nuevos oligopeptidos triflu-orometilados - Google Patents
Procedimiento de preparacion de nuevos oligopeptidos triflu-orometiladosInfo
- Publication number
- ES466993A1 ES466993A1 ES466993A ES466993A ES466993A1 ES 466993 A1 ES466993 A1 ES 466993A1 ES 466993 A ES466993 A ES 466993A ES 466993 A ES466993 A ES 466993A ES 466993 A1 ES466993 A1 ES 466993A1
- Authority
- ES
- Spain
- Prior art keywords
- trifluoromethylated
- oligopeptides
- lys
- ala
- image
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06191—Dipeptides containing heteroatoms different from O, S, or N
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Procedimiento de preparación de nuevos oligopéptidos trifluorometilados de fórmula **fórmula** en la que el pa -X-Y representa: sea el encadenamiento-L-Ala-L-Ala, en cuyo caso R designa un átomo de hidrógeno, un grupo nitro o trifluorometilo situado en posición meta, o un átomo de cloro o un grupo nitro, trifluorometilo, metoxi, isopropilo, ciano o carboxilo situado en posición para, sea el encadenamiento-L-Lis-L-Ala, en cuyo caso R designa , un átomo de hidrógeno, o un grupo trifluorometilo, metilo, isopropilo, N, N-dimetilamino o acetilo situado en posición para, sea el encadenamiento-L-Ala, Dl¿Ala, en cuyo caso R designa un átomo de hidrógeno.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7704713A FR2381023A1 (fr) | 1977-02-18 | 1977-02-18 | Nouveaux oligopeptides trifluoromethyles derives de la l-alanine, leur procede de preparation et leur application en therapeutique |
Publications (1)
Publication Number | Publication Date |
---|---|
ES466993A1 true ES466993A1 (es) | 1979-06-01 |
Family
ID=9186934
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES466993A Expired ES466993A1 (es) | 1977-02-18 | 1978-02-15 | Procedimiento de preparacion de nuevos oligopeptidos triflu-orometilados |
Country Status (14)
Country | Link |
---|---|
US (1) | US4153688A (es) |
JP (1) | JPS53103431A (es) |
AU (1) | AU3323378A (es) |
BE (1) | BE863969A (es) |
DE (1) | DE2806833A1 (es) |
ES (1) | ES466993A1 (es) |
FR (1) | FR2381023A1 (es) |
GB (1) | GB1564883A (es) |
GR (1) | GR62092B (es) |
IT (1) | IT1095356B (es) |
LU (1) | LU79069A1 (es) |
NL (1) | NL7801835A (es) |
SE (1) | SE7801649L (es) |
ZA (1) | ZA78859B (es) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1134503B (it) | 1980-11-28 | 1986-08-13 | Proter Spa | Composti della diclorodietilaminofenilalanina ad azione antitumorale |
US4540683A (en) * | 1978-07-31 | 1985-09-10 | Proter S.P.A. | In vitro and in vivo treatment of cancer cells and treatment of viruses with a tripeptide compound |
US4740501A (en) * | 1978-07-31 | 1988-04-26 | Debarbieri Augusto | Interference of b-type retrovirus replication with a tripeptide compound |
US4743590A (en) * | 1978-07-31 | 1988-05-10 | Debarbieri Augusto | In vitro and in vivo treatment of cancer cells and treatment of viruses with a tripeptide compound |
US4666887A (en) * | 1980-11-28 | 1987-05-19 | Proter S.P.A. | Intravenous or intraperitoneal administration of a tripeptide compound for treating cancer |
CS226907B1 (en) * | 1981-08-07 | 1984-04-16 | Kasafirek Evzen | Alkylamides of carboxyalkanoylpeptides |
US4518528A (en) * | 1983-05-19 | 1985-05-21 | Rasnick David W | α Amino fluoro ketones |
US4683292A (en) * | 1983-08-12 | 1987-07-28 | Immunetech, Inc. | Immunotherapeutic polypeptide agents which bind to lymphocyte immunoglobulin FC receptors |
US6184210B1 (en) * | 1997-10-10 | 2001-02-06 | Cytovia, Inc. | Dipeptide apoptosis inhibitors and the use thereof |
KR20010041905A (ko) * | 1998-03-16 | 2001-05-25 | 시토비아 인크. | 디펩티드 카스파제 억제제 및 이의 용도 |
JP2002539183A (ja) | 1999-03-16 | 2002-11-19 | サイトビア インコーポレイテッド | 置換2−アミノベンズアミドカスパーゼインヒビターおよびその使用 |
DE60035037T2 (de) | 1999-04-09 | 2008-01-31 | Cytovia, Inc., San Diego | Caspase inhibitoren und ihre verwendung |
DE60040397D1 (de) | 1999-08-27 | 2008-11-13 | Cytovia Inc | Substituierte alpha-hydroxy-säuren als caspase-hemmer und ihre verwendung |
US6566338B1 (en) | 1999-10-12 | 2003-05-20 | Cytovia, Inc. | Caspase inhibitors for the treatment and prevention of chemotherapy and radiation therapy induced cell death |
AU2004284089B2 (en) | 2003-10-24 | 2009-11-26 | Aventis Pharmaceuticals Inc. | Novel keto-oxadiazole derivatives as cathepsin inhibitors |
DE102006062234A1 (de) * | 2006-12-22 | 2008-06-26 | Voith Patent Gmbh | Verfahren und Vorrichtung zur Trocknung einer Faserstoffbahn |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1080564B (de) * | 1959-02-17 | 1960-04-28 | Hoechst Ag | Verfahren zur N-Trifluoracetylierung von Aminosaeuren und Peptiden |
US3985723A (en) * | 1971-09-07 | 1976-10-12 | The University Of Mississippi | Trifluoroacetylation process |
-
1977
- 1977-02-18 FR FR7704713A patent/FR2381023A1/fr active Granted
-
1978
- 1978-02-09 US US05/876,500 patent/US4153688A/en not_active Expired - Lifetime
- 1978-02-10 GR GR55420A patent/GR62092B/el unknown
- 1978-02-10 GB GB5360/78A patent/GB1564883A/en not_active Expired
- 1978-02-13 SE SE7801649A patent/SE7801649L/xx unknown
- 1978-02-13 AU AU33233/78A patent/AU3323378A/en active Pending
- 1978-02-14 ZA ZA00780859A patent/ZA78859B/xx unknown
- 1978-02-15 BE BE185176A patent/BE863969A/xx unknown
- 1978-02-15 LU LU79069A patent/LU79069A1/xx unknown
- 1978-02-15 ES ES466993A patent/ES466993A1/es not_active Expired
- 1978-02-16 JP JP1710778A patent/JPS53103431A/ja active Pending
- 1978-02-16 IT IT20264/78A patent/IT1095356B/it active
- 1978-02-17 NL NL7801835A patent/NL7801835A/xx not_active Application Discontinuation
- 1978-02-17 DE DE19782806833 patent/DE2806833A1/de not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
BE863969A (fr) | 1978-08-16 |
IT7820264A0 (it) | 1978-02-16 |
ZA78859B (en) | 1979-01-31 |
JPS53103431A (en) | 1978-09-08 |
SE7801649L (sv) | 1978-08-19 |
GB1564883A (en) | 1980-04-16 |
IT1095356B (it) | 1985-08-10 |
FR2381023B1 (es) | 1979-06-01 |
LU79069A1 (fr) | 1978-06-27 |
DE2806833A1 (de) | 1978-08-24 |
FR2381023A1 (fr) | 1978-09-15 |
GR62092B (en) | 1979-02-22 |
NL7801835A (nl) | 1978-08-22 |
AU3323378A (en) | 1979-08-23 |
US4153688A (en) | 1979-05-08 |
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