ES466993A1 - Procedimiento de preparacion de nuevos oligopeptidos triflu-orometilados - Google Patents

Procedimiento de preparacion de nuevos oligopeptidos triflu-orometilados

Info

Publication number
ES466993A1
ES466993A1 ES466993A ES466993A ES466993A1 ES 466993 A1 ES466993 A1 ES 466993A1 ES 466993 A ES466993 A ES 466993A ES 466993 A ES466993 A ES 466993A ES 466993 A1 ES466993 A1 ES 466993A1
Authority
ES
Spain
Prior art keywords
trifluoromethylated
oligopeptides
lys
ala
image
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES466993A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Delalande SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Delalande SA filed Critical Delalande SA
Publication of ES466993A1 publication Critical patent/ES466993A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06191—Dipeptides containing heteroatoms different from O, S, or N
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Procedimiento de preparación de nuevos oligopéptidos trifluorometilados de fórmula **fórmula** en la que el pa -X-Y representa: sea el encadenamiento-L-Ala-L-Ala, en cuyo caso R designa un átomo de hidrógeno, un grupo nitro o trifluorometilo situado en posición meta, o un átomo de cloro o un grupo nitro, trifluorometilo, metoxi, isopropilo, ciano o carboxilo situado en posición para, sea el encadenamiento-L-Lis-L-Ala, en cuyo caso R designa , un átomo de hidrógeno, o un grupo trifluorometilo, metilo, isopropilo, N, N-dimetilamino o acetilo situado en posición para, sea el encadenamiento-L-Ala, Dl¿Ala, en cuyo caso R designa un átomo de hidrógeno.
ES466993A 1977-02-18 1978-02-15 Procedimiento de preparacion de nuevos oligopeptidos triflu-orometilados Expired ES466993A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7704713A FR2381023A1 (fr) 1977-02-18 1977-02-18 Nouveaux oligopeptides trifluoromethyles derives de la l-alanine, leur procede de preparation et leur application en therapeutique

Publications (1)

Publication Number Publication Date
ES466993A1 true ES466993A1 (es) 1979-06-01

Family

ID=9186934

Family Applications (1)

Application Number Title Priority Date Filing Date
ES466993A Expired ES466993A1 (es) 1977-02-18 1978-02-15 Procedimiento de preparacion de nuevos oligopeptidos triflu-orometilados

Country Status (14)

Country Link
US (1) US4153688A (es)
JP (1) JPS53103431A (es)
AU (1) AU3323378A (es)
BE (1) BE863969A (es)
DE (1) DE2806833A1 (es)
ES (1) ES466993A1 (es)
FR (1) FR2381023A1 (es)
GB (1) GB1564883A (es)
GR (1) GR62092B (es)
IT (1) IT1095356B (es)
LU (1) LU79069A1 (es)
NL (1) NL7801835A (es)
SE (1) SE7801649L (es)
ZA (1) ZA78859B (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1134503B (it) 1980-11-28 1986-08-13 Proter Spa Composti della diclorodietilaminofenilalanina ad azione antitumorale
US4743590A (en) * 1978-07-31 1988-05-10 Debarbieri Augusto In vitro and in vivo treatment of cancer cells and treatment of viruses with a tripeptide compound
US4740501A (en) * 1978-07-31 1988-04-26 Debarbieri Augusto Interference of b-type retrovirus replication with a tripeptide compound
US4540683A (en) * 1978-07-31 1985-09-10 Proter S.P.A. In vitro and in vivo treatment of cancer cells and treatment of viruses with a tripeptide compound
US4666887A (en) * 1980-11-28 1987-05-19 Proter S.P.A. Intravenous or intraperitoneal administration of a tripeptide compound for treating cancer
CS226907B1 (en) * 1981-08-07 1984-04-16 Kasafirek Evzen Alkylamides of carboxyalkanoylpeptides
US4518528A (en) * 1983-05-19 1985-05-21 Rasnick David W α Amino fluoro ketones
US4683292A (en) * 1983-08-12 1987-07-28 Immunetech, Inc. Immunotherapeutic polypeptide agents which bind to lymphocyte immunoglobulin FC receptors
US6184210B1 (en) 1997-10-10 2001-02-06 Cytovia, Inc. Dipeptide apoptosis inhibitors and the use thereof
WO1999047154A1 (en) * 1998-03-16 1999-09-23 Cytovia, Inc. Dipeptide caspase inhibitors and the use thereof
JP2002539183A (ja) * 1999-03-16 2002-11-19 サイトビア インコーポレイテッド 置換２−アミノベンズアミドカスパーゼインヒビターおよびその使用
KR20020005665A (ko) 1999-04-09 2002-01-17 추후보정 카스파제 저해제 및 그것의 용도
ATE409688T1 (de) 1999-08-27 2008-10-15 Cytovia Inc Substituierte alpha-hydroxy-säuren als caspase- hemmer und ihre verwendung
US6566338B1 (en) 1999-10-12 2003-05-20 Cytovia, Inc. Caspase inhibitors for the treatment and prevention of chemotherapy and radiation therapy induced cell death
RU2346943C2 (ru) * 2003-10-24 2009-02-20 Авентис Фармасьютикалз Инк. Новые соединения и композиции в качестве ингибиторов катепсина
DE102006062234A1 (de) * 2006-12-22 2008-06-26 Voith Patent Gmbh Verfahren und Vorrichtung zur Trocknung einer Faserstoffbahn

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1080564B (de) * 1959-02-17 1960-04-28 Hoechst Ag Verfahren zur N-Trifluoracetylierung von Aminosaeuren und Peptiden
US3985723A (en) * 1971-09-07 1976-10-12 The University Of Mississippi Trifluoroacetylation process

Also Published As

Publication number Publication date
DE2806833A1 (de) 1978-08-24
BE863969A (fr) 1978-08-16
ZA78859B (en) 1979-01-31
SE7801649L (sv) 1978-08-19
FR2381023B1 (es) 1979-06-01
AU3323378A (en) 1979-08-23
GB1564883A (en) 1980-04-16
GR62092B (en) 1979-02-22
NL7801835A (nl) 1978-08-22
FR2381023A1 (fr) 1978-09-15
IT1095356B (it) 1985-08-10
US4153688A (en) 1979-05-08
IT7820264A0 (it) 1978-02-16
JPS53103431A (en) 1978-09-08
LU79069A1 (fr) 1978-06-27

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