ES466237A1 - Procedimiento para la obtencion de una nueva propilamina sustituida. - Google Patents
Procedimiento para la obtencion de una nueva propilamina sustituida.Info
- Publication number
- ES466237A1 ES466237A1 ES466237A ES466237A ES466237A1 ES 466237 A1 ES466237 A1 ES 466237A1 ES 466237 A ES466237 A ES 466237A ES 466237 A ES466237 A ES 466237A ES 466237 A1 ES466237 A1 ES 466237A1
- Authority
- ES
- Spain
- Prior art keywords
- pyrrolidino
- isobutoxy
- phenyl
- salts
- propylamine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000003839 salts Chemical class 0.000 title 1
- 206010002383 Angina Pectoris Diseases 0.000 abstract 1
- 238000009835 boiling Methods 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000002526 effect on cardiovascular system Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/15—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7702058A FR2378024A1 (fr) | 1977-01-25 | 1977-01-25 | Nouvelle propylamine substituee, obtention et application |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES466237A1 true ES466237A1 (es) | 1978-10-16 |
Family
ID=9185890
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES466237A Expired ES466237A1 (es) | 1977-01-25 | 1978-01-21 | Procedimiento para la obtencion de una nueva propilamina sustituida. |
Country Status (12)
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3278160D1 (en) * | 1981-12-28 | 1988-04-07 | Carter Wallace | Process for the preparation of b-û(2-methylpropoxy)-methyl¨-n-phenyl-n-(phenylmethyl)-1-pyrrolidineethanamine |
| DK156396C (da) * | 1983-09-27 | 1990-01-08 | Cerm Cent Europ Rech Mauvernay | 2-(n-pyrrolidino)-3-isobutoxy-n-substituerede phenyl-n-benzyl-propylamin-forbindelser og farmaceutiske midler indeholdende disse |
| FI852690A0 (fi) * | 1983-11-11 | 1985-07-08 | Akzo Nv | Etrar av n-propanolaminderivat. |
| GB8330197D0 (en) * | 1983-11-11 | 1983-12-21 | Akzo Nv | Ether of n-propanolamine derivative |
| FR2558159B1 (fr) * | 1984-01-18 | 1986-06-13 | Cerm Cent Europ Rech Mauvernay | 3-alkoxy 2-(n-pyrrolidino)-n-pyridyl-n-arylmethyl-propylamines, leur preparation et leur application en therapeutique |
| FR2558161B1 (fr) * | 1984-01-18 | 1987-01-23 | Cerm Cent Europ Rech Mauvernay | 3-alkoxy 2-(n-pyrrolidino) n-furylmethyl ou n-thienylmethyl n-pyridyl propylamines, leur preparation et leur application en therapeutique |
| FR2558160B1 (fr) * | 1984-01-18 | 1986-05-30 | Cerm Cent Europ Rech Mauvernay | 3-alkoxy 2-(n-pyrrolidino)-n-pyrimidinyl ou -pyrazinyl propylamines, leur preparation et leur application en therapeutique |
| DE3726632A1 (de) * | 1987-08-11 | 1989-05-18 | Boehringer Mannheim Gmbh | 1,2-diamino-verbindungen, verfahren zu ihrer herstellung sowie arzneimittel, die diese verbindungen enthalten |
| DE3726633A1 (de) * | 1987-08-11 | 1989-02-23 | Boehringer Mannheim Gmbh | Neue 1,2-diamino-verbindungen, verfahren zu ihrer herstellung sowie arzneimittel, die diese verbindungen enthalten |
| JP2678758B2 (ja) * | 1988-02-16 | 1997-11-17 | 興和株式会社 | 新規なプロパン誘導体 |
| WO2016098128A1 (en) * | 2014-12-16 | 2016-06-23 | Council Of Scientific & Industrial Research | Process for the preparation of bepridil |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE795735A (fr) * | 1972-03-06 | 1973-06-18 | Cerm Cent Europ Rech Mauvernay | Nouvelles ethylenediamines substituees a activite cardiovasculaire |
-
1977
- 1977-01-25 FR FR7702058A patent/FR2378024A1/fr active Granted
- 1977-10-03 JP JP11797777A patent/JPS5392764A/ja active Granted
-
1978
- 1978-01-11 CH CH27378A patent/CH628889A5/fr not_active IP Right Cessation
- 1978-01-13 GB GB1506/78A patent/GB1595031A/en not_active Expired
- 1978-01-16 IL IL53816A patent/IL53816A0/xx not_active IP Right Cessation
- 1978-01-20 NL NLAANVRAGE7800753,A patent/NL189258C/xx not_active IP Right Cessation
- 1978-01-20 PT PT67556A patent/PT67556B/pt unknown
- 1978-01-21 ES ES466237A patent/ES466237A1/es not_active Expired
- 1978-01-23 AU AU32660/78A patent/AU516479B2/en not_active Expired
- 1978-01-23 BE BE184554A patent/BE863214A/xx not_active IP Right Cessation
- 1978-01-24 DE DE2802864A patent/DE2802864C2/de not_active Expired
- 1978-01-24 ZA ZA00780426A patent/ZA78426B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CH628889A5 (en) | 1982-03-31 |
| NL7800753A (nl) | 1978-07-27 |
| GB1595031A (en) | 1981-08-05 |
| DE2802864A1 (de) | 1978-07-27 |
| JPS5429493B2 (enrdf_load_stackoverflow) | 1979-09-25 |
| AU3266078A (en) | 1979-08-02 |
| FR2378024B1 (enrdf_load_stackoverflow) | 1979-05-11 |
| DE2802864C2 (de) | 1982-12-09 |
| AU516479B2 (en) | 1981-06-04 |
| NL189258B (nl) | 1992-09-16 |
| ZA78426B (en) | 1979-01-31 |
| PT67556A (fr) | 1978-02-01 |
| PT67556B (fr) | 1979-06-18 |
| NL189258C (nl) | 1993-02-16 |
| BE863214A (fr) | 1978-07-24 |
| FR2378024A1 (fr) | 1978-08-18 |
| IL53816A0 (en) | 1978-04-30 |
| JPS5392764A (en) | 1978-08-15 |
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