ES463782A1 - Un procedimiento para la preparacion de derivados de benza- zepina. - Google Patents
Un procedimiento para la preparacion de derivados de benza- zepina.Info
- Publication number
- ES463782A1 ES463782A1 ES463782A ES463782A ES463782A1 ES 463782 A1 ES463782 A1 ES 463782A1 ES 463782 A ES463782 A ES 463782A ES 463782 A ES463782 A ES 463782A ES 463782 A1 ES463782 A1 ES 463782A1
- Authority
- ES
- Spain
- Prior art keywords
- trans
- decahydrobenzazepines
- aryl
- phenyl
- substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- MYOAKAGSEUSIMT-UHFFFAOYSA-N 1h-3-benzazepine Chemical class C1C=NC=CC2=CC=CC=C12 MYOAKAGSEUSIMT-UHFFFAOYSA-N 0.000 abstract 1
- 239000000556 agonist Substances 0.000 abstract 1
- 229940035676 analgesics Drugs 0.000 abstract 1
- 239000005557 antagonist Substances 0.000 abstract 1
- 239000000730 antalgic agent Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000003533 narcotic effect Effects 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/62—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by hydrogenation of carbon-to-carbon double or triple bonds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/16—Benzazepines; Hydrogenated benzazepines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Hematology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/737,959 US4141894A (en) | 1976-11-02 | 1976-11-02 | Trans-5a-aryl-decahydrobenzazepines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES463782A1 true ES463782A1 (es) | 1978-12-16 |
Family
ID=24965985
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES463782A Expired ES463782A1 (es) | 1976-11-02 | 1977-11-02 | Un procedimiento para la preparacion de derivados de benza- zepina. |
Country Status (26)
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT1298132E (pt) * | 2000-07-06 | 2007-01-31 | Sankyo Co | Sais de adição de ácido derivados de hidropiridina |
| FR3062850B1 (fr) * | 2017-02-10 | 2020-01-31 | Guerbet | Procede de preparation monotope de composes organo-iodes |
| FR3084668A1 (fr) | 2018-08-02 | 2020-02-07 | Guerbet | Procede de preparation monotope de composes organo-iodes intermediaires a la synthese du ioversol |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AT330179B (de) * | 1972-07-20 | 1976-06-25 | Du Pont | Verfahren zur herstellung von neuen 4a-aryl- transdecahydroisochinolinderivaten sowie deren optischen isomeren |
| US4001248A (en) * | 1974-06-07 | 1977-01-04 | Eli Lilly And Company | N-cycloalkylmethyl decahydroisoquinolines |
| US4001247A (en) * | 1974-06-07 | 1977-01-04 | Eli Lilly And Company | 1-ethyl 3a-(substituted-phenyl) decahydroisoquinoline |
-
1976
- 1976-11-02 US US05/737,959 patent/US4141894A/en not_active Expired - Lifetime
-
1977
- 1977-10-26 PT PT67195A patent/PT67195B/pt unknown
- 1977-10-27 GB GB44728/77A patent/GB1585296A/en not_active Expired
- 1977-10-27 YU YU02575/77A patent/YU257577A/xx unknown
- 1977-10-27 CA CA289,686A patent/CA1096861A/en not_active Expired
- 1977-10-27 IL IL53235A patent/IL53235A0/xx unknown
- 1977-10-28 FR FR7732777A patent/FR2369268A1/fr active Granted
- 1977-10-28 DE DE19772748468 patent/DE2748468A1/de not_active Withdrawn
- 1977-10-28 SE SE7712219A patent/SE7712219L/xx unknown
- 1977-10-28 IE IE2204/77A patent/IE45899B1/en unknown
- 1977-10-28 PH PH20378A patent/PH13506A/en unknown
- 1977-10-28 BE BE1008484A patent/BE860315A/xx unknown
- 1977-10-31 AR AR269798A patent/AR221835A1/es active
- 1977-11-01 DK DK485177A patent/DK485177A/da unknown
- 1977-11-01 NL NL7712052A patent/NL7712052A/xx not_active Application Discontinuation
- 1977-11-01 AU AU30233/77A patent/AU510911B2/en not_active Expired
- 1977-11-01 BG BG7737703A patent/BG28417A3/xx unknown
- 1977-11-01 ZA ZA00776498A patent/ZA776498B/xx unknown
- 1977-11-01 SU SU772539354A patent/SU843743A3/ru active
- 1977-11-02 DD DD7700201832A patent/DD133797A5/xx unknown
- 1977-11-02 AT AT782277A patent/AT358046B/de not_active IP Right Cessation
- 1977-11-02 ES ES463782A patent/ES463782A1/es not_active Expired
- 1977-11-02 RO RO7792004A patent/RO72899B/ro unknown
- 1977-11-02 JP JP13211277A patent/JPS5356683A/ja active Pending
- 1977-11-02 PL PL1977201883A patent/PL108916B1/pl unknown
-
1980
- 1980-08-14 CA CA358,214A patent/CA1102319A/en not_active Expired
- 1980-09-29 GR GR54663A patent/GR70052B/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BG28417A3 (en) | 1980-04-15 |
| SU843743A3 (ru) | 1981-06-30 |
| BE860315A (fr) | 1978-04-28 |
| FR2369268B1 (US06534493-20030318-C00166.png) | 1980-05-16 |
| DK485177A (da) | 1978-05-03 |
| AU3023377A (en) | 1979-05-10 |
| ZA776498B (en) | 1979-06-27 |
| DE2748468A1 (de) | 1978-05-03 |
| PL108916B1 (en) | 1980-05-31 |
| AT358046B (de) | 1980-08-11 |
| CA1102319A (en) | 1981-06-02 |
| JPS5356683A (en) | 1978-05-23 |
| NL7712052A (nl) | 1978-05-05 |
| RO72899B (ro) | 1981-03-22 |
| PT67195B (en) | 1979-03-23 |
| IE45899B1 (en) | 1982-12-29 |
| PT67195A (en) | 1977-11-01 |
| US4141894A (en) | 1979-02-27 |
| GR70052B (US06534493-20030318-C00166.png) | 1982-07-26 |
| CA1096861A (en) | 1981-03-03 |
| SE7712219L (sv) | 1978-05-03 |
| ATA782277A (de) | 1980-01-15 |
| GB1585296A (en) | 1981-02-25 |
| PL201883A1 (pl) | 1979-01-29 |
| DD133797A5 (de) | 1979-01-24 |
| IE45899L (en) | 1978-05-02 |
| IL53235A0 (en) | 1977-12-30 |
| AR221835A1 (es) | 1981-03-31 |
| YU257577A (en) | 1983-01-21 |
| FR2369268A1 (fr) | 1978-05-26 |
| AU510911B2 (en) | 1980-07-17 |
| PH13506A (en) | 1980-06-03 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IT1206501B (it) | Composizioni analgesiche, e antiinfiammatorie migliorate, contenenti caffeina. | |
| ES475379A1 (es) | Procedimiento para la obtencion de 1,4-dihidropiridinas ni- tro-sustituidas | |
| NZ183605A (en) | Hentriakontapeptides having opiate agonist activity | |
| IL55361A (en) | Machine for mixing and distributing loose materials, such as animal feestuffs | |
| IL52872A (en) | Analgesic pentapeptides,their preparation and pharmaceutical compositions containing them | |
| NZ185965A (en) | 5'-deoxy-5-fluor ocytidine, 5'-deoxy-5-fluoro-uridine and pharmaceutical compositions | |
| PH16512A (en) | N-(phenylalkylamino-alkyl)-dihydroisoquinolinones,pharmaceutical compositions and methods employing them | |
| IL51945A0 (en) | New naphthalene derivatives their prodiction and pharmaceutical compositions containing them | |
| IT1143693B (it) | 2,3-diidroimidazol (2,1-b) tiazoli,fenil-sostituiti nelle posizioni 5 e 6,aventi attivita' antiartritica,procedimento per loro preparazione e composizioni farmaceutiche che li contengono | |
| BE848496A (fr) | Derives d'amino-alcools, leur preparation et utilisation, ainsi que compositions contenant ces derives. | |
| IL56028A (en) | Peptides and derivatives thereof exhibiting morphine agonist activity,their preparation and pharmaceutical compositions containing them | |
| ES438315A1 (es) | Un procedimiento para preparar compuestos de decahidroiso- quinolina. | |
| IT1057953B (it) | Perfezionamento nelle frese per alesuture | |
| IL51309A0 (en) | New 1,2-benzisothiazolin-3-ones,their preparation and pharmaceutical compositions containing them | |
| IL51360A (en) | Peptides having analgesic activity,their production and pharmaceutical compositions containing them | |
| ES458537A1 (es) | Procedimiento para preparar encefalinas 2-y-3-sustituidas. | |
| ES463782A1 (es) | Un procedimiento para la preparacion de derivados de benza- zepina. | |
| ES8105148A1 (es) | Un procedimiento para la preparacion de una composicion far-maceutica de quinazolinonas analgesicas | |
| NZ184634A (en) | N-(i'allyl-2-pyrrolidylmethyl)-2,3-dimethoxy-5-sulphamoyl-benzamide and pharmaceutical compositions | |
| DD130989A5 (de) | Zufuehr-und mischduese | |
| NZ185539A (en) | Cis-4a-aryl-2-substituted-2,3,4,4a,5,6,7,7a-octa hydro-1h-2-pyrindines and pharmaceutical compositions | |
| ES2098263T3 (es) | 8-alfa-acilamino-ergolinas, su preparacion y su utilizacion como medicamentos. | |
| PL196355A1 (pl) | Sposob mikrobiologicznego wytwarzania mieszaniny androstadieno-1,4-dionu-3,17 i androsteno-4-dionu-3,17 | |
| ES472121A1 (es) | Un procedimiento para preparar compuestos azepina. | |
| DE68901311D1 (de) | Schmiermittelgemisch. |