ES462545A1 - Procedimiento para preparar pehidro-indolinoles. - Google Patents
Procedimiento para preparar pehidro-indolinoles.Info
- Publication number
- ES462545A1 ES462545A1 ES462545A ES462545A ES462545A1 ES 462545 A1 ES462545 A1 ES 462545A1 ES 462545 A ES462545 A ES 462545A ES 462545 A ES462545 A ES 462545A ES 462545 A1 ES462545 A1 ES 462545A1
- Authority
- ES
- Spain
- Prior art keywords
- carbon atoms
- alkoxy
- hydrogen
- indolinols
- hexahydro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Abstract
Procedimiento para preparar perhidro-indolinoles, de fórmula I **(Fórmula)** en la que R1 y R2 significan, independientemente la una de la otra, hidrógeno, flúor, cloro, trifluorometilo, alquilo que contiene de 1 a 4 átomos de carbono, o alcoxi que contiene de 1 a 4 átomos de carbono, con el requisito de que cuando el símbolo R3 es alcoxi, uno de los símbolos R1 y R2, como mínimo, signifique alcoxi, o bien R1 y R2 están unidas a 2 átomos de carbono adyacentes al ciclo bencénico y forman juntamente un resto -(CH2)m-, en el que m significa 3 ó 4, o un resto -CH=CH-CH=CH- ú -O-CH2-X, en donde X significa -O- ó -CH2-, y R3 significa hidrógeno, flúor, cloro, trifluorometilo, alquilo que contiene de 1 a 4 átomos de carbono, o alcoxi que contiene de 1 a 4 átomos de carbono.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH1200176 | 1976-09-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES462545A1 true ES462545A1 (es) | 1979-05-01 |
Family
ID=4378903
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES462545A Expired ES462545A1 (es) | 1976-09-22 | 1977-09-22 | Procedimiento para preparar pehidro-indolinoles. |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US4129658A (es) |
| JP (1) | JPS5340766A (es) |
| AU (1) | AU2893177A (es) |
| BE (1) | BE858887A (es) |
| DE (1) | DE2741009A1 (es) |
| DK (1) | DK407077A (es) |
| ES (1) | ES462545A1 (es) |
| FI (1) | FI772695A (es) |
| FR (1) | FR2365557A1 (es) |
| IL (1) | IL52962A0 (es) |
| NL (1) | NL7710181A (es) |
| NZ (1) | NZ185214A (es) |
| PH (1) | PH13885A (es) |
| PT (1) | PT67058B (es) |
| SE (1) | SE7710238L (es) |
| ZA (1) | ZA775687B (es) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4194002A (en) * | 1978-03-29 | 1980-03-18 | Sandoz, Inc. | Cholesterol ester-reducing amides of hexahydroindolinols |
| UA80543C2 (en) * | 2001-12-04 | 2007-10-10 | Wyeth Corp | Method for the preparation of o-desmethylvenlafaxine |
| GB0128996D0 (en) * | 2001-12-04 | 2002-01-23 | Novartis Ag | Organic compounds |
| WO2019025931A1 (en) | 2017-07-31 | 2019-02-07 | Novartis Ag | USE OF A MUSSEL FOR REDUCING THE USE OF COCAINE OR FOR PREVENTING A RECHUTE IN THE USE OF COCAINE |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3635956A (en) * | 1968-03-01 | 1972-01-18 | Squibb & Sons Inc | Benzothiazines related compounds derivatives and salts thereof |
| CH601226A5 (es) * | 1974-12-06 | 1978-06-30 | Sandoz Ag | |
| DE2718369A1 (de) | 1976-05-07 | 1977-11-17 | Sandoz Ag | Neue 4-phenyl-hexahydro-4-indolinol- derivate, ihre verwendung und herstellung |
| DE2722854A1 (de) | 1976-05-31 | 1977-12-15 | Sandoz Ag | Hexahydro-4-phenyl-4-hydroxyindoline, ihre verwendung und herstellung |
-
1977
- 1977-09-12 DE DE19772741009 patent/DE2741009A1/de not_active Withdrawn
- 1977-09-13 SE SE7710238A patent/SE7710238L/xx unknown
- 1977-09-13 FI FI772695A patent/FI772695A/fi not_active Application Discontinuation
- 1977-09-13 DK DK407077A patent/DK407077A/da unknown
- 1977-09-16 NL NL7710181A patent/NL7710181A/xx not_active Application Discontinuation
- 1977-09-19 US US05/834,103 patent/US4129658A/en not_active Expired - Lifetime
- 1977-09-19 FR FR7728135A patent/FR2365557A1/fr not_active Withdrawn
- 1977-09-20 BE BE181064A patent/BE858887A/xx unknown
- 1977-09-20 PT PT67058A patent/PT67058B/pt unknown
- 1977-09-20 NZ NZ185214A patent/NZ185214A/xx unknown
- 1977-09-20 PH PH20254A patent/PH13885A/en unknown
- 1977-09-20 AU AU28931/77A patent/AU2893177A/en active Pending
- 1977-09-20 IL IL52962A patent/IL52962A0/xx unknown
- 1977-09-21 JP JP11274177A patent/JPS5340766A/ja active Pending
- 1977-09-22 ZA ZA00775687A patent/ZA775687B/xx unknown
- 1977-09-22 ES ES462545A patent/ES462545A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| FR2365557A1 (fr) | 1978-04-21 |
| SE7710238L (sv) | 1978-03-23 |
| AU2893177A (en) | 1979-03-29 |
| FI772695A (fi) | 1978-03-23 |
| PT67058B (fr) | 1979-05-14 |
| PH13885A (en) | 1980-10-27 |
| ZA775687B (en) | 1979-04-25 |
| NZ185214A (en) | 1980-03-05 |
| DK407077A (da) | 1978-03-23 |
| JPS5340766A (en) | 1978-04-13 |
| BE858887A (fr) | 1978-03-20 |
| NL7710181A (nl) | 1978-03-28 |
| IL52962A0 (en) | 1977-11-30 |
| DE2741009A1 (de) | 1978-03-23 |
| US4129658A (en) | 1978-12-12 |
| PT67058A (fr) | 1977-10-01 |
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