ES462069A1 - Procedimiento para el enriquecimiento de proteina de teji- dos. - Google Patents
Procedimiento para el enriquecimiento de proteina de teji- dos.Info
- Publication number
- ES462069A1 ES462069A1 ES462069A ES462069A ES462069A1 ES 462069 A1 ES462069 A1 ES 462069A1 ES 462069 A ES462069 A ES 462069A ES 462069 A ES462069 A ES 462069A ES 462069 A1 ES462069 A1 ES 462069A1
- Authority
- ES
- Spain
- Prior art keywords
- tissue specific
- protein
- specific protein
- preparing same
- acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 102000004169 proteins and genes Human genes 0.000 title abstract 4
- 108090000623 proteins and genes Proteins 0.000 title abstract 4
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 235000018102 proteins Nutrition 0.000 abstract 3
- MSWZFWKMSRAUBD-UHFFFAOYSA-N 2-Amino-2-Deoxy-Hexose Chemical compound NC1C(O)OC(CO)C(O)C1O MSWZFWKMSRAUBD-UHFFFAOYSA-N 0.000 abstract 1
- WRFPVMFCRNYQNR-UHFFFAOYSA-N 2-hydroxyphenylalanine Chemical compound OC(=O)C(N)CC1=CC=CC=C1O WRFPVMFCRNYQNR-UHFFFAOYSA-N 0.000 abstract 1
- CERZMXAJYMMUDR-QBTAGHCHSA-N 5-amino-3,5-dideoxy-D-glycero-D-galacto-non-2-ulopyranosonic acid Chemical compound N[C@@H]1[C@@H](O)CC(O)(C(O)=O)O[C@H]1[C@H](O)[C@H](O)CO CERZMXAJYMMUDR-QBTAGHCHSA-N 0.000 abstract 1
- 239000004475 Arginine Substances 0.000 abstract 1
- SHZGCJCMOBCMKK-UHFFFAOYSA-N D-mannomethylose Natural products CC1OC(O)C(O)C(O)C1O SHZGCJCMOBCMKK-UHFFFAOYSA-N 0.000 abstract 1
- PNNNRSAQSRJVSB-SLPGGIOYSA-N Fucose Natural products C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)C=O PNNNRSAQSRJVSB-SLPGGIOYSA-N 0.000 abstract 1
- 239000004471 Glycine Substances 0.000 abstract 1
- SHZGCJCMOBCMKK-DHVFOXMCSA-N L-fucopyranose Chemical compound C[C@@H]1OC(O)[C@@H](O)[C@H](O)[C@@H]1O SHZGCJCMOBCMKK-DHVFOXMCSA-N 0.000 abstract 1
- QIVBCDIJIAJPQS-VIFPVBQESA-N L-tryptophane Chemical compound C1=CC=C2C(C[C@H](N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-VIFPVBQESA-N 0.000 abstract 1
- 239000004472 Lysine Substances 0.000 abstract 1
- 239000004473 Threonine Substances 0.000 abstract 1
- QIVBCDIJIAJPQS-UHFFFAOYSA-N Tryptophan Natural products C1=CC=C2C(CC(N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-UHFFFAOYSA-N 0.000 abstract 1
- 150000001371 alpha-amino acids Chemical class 0.000 abstract 1
- 235000008206 alpha-amino acids Nutrition 0.000 abstract 1
- 229940024606 amino acid Drugs 0.000 abstract 1
- 235000001014 amino acid Nutrition 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 150000001720 carbohydrates Chemical class 0.000 abstract 1
- 239000000470 constituent Substances 0.000 abstract 1
- 229960003067 cystine Drugs 0.000 abstract 1
- 239000004220 glutamic acid Substances 0.000 abstract 1
- 150000002402 hexoses Chemical class 0.000 abstract 1
- 229960000310 isoleucine Drugs 0.000 abstract 1
- CERZMXAJYMMUDR-UHFFFAOYSA-N neuraminic acid Natural products NC1C(O)CC(O)(C(O)=O)OC1C(O)C(O)CO CERZMXAJYMMUDR-UHFFFAOYSA-N 0.000 abstract 1
- 238000004062 sedimentation Methods 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 239000004474 valine Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4715—Pregnancy proteins, e.g. placenta proteins, alpha-feto-protein, pregnancy specific beta glycoprotein
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/806—Antigenic peptides or proteins
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/827—Proteins from mammals or birds
- Y10S530/85—Reproductive organs or embryos
- Y10S530/851—Placenta; amniotic fluid
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Reproductive Health (AREA)
- Biochemistry (AREA)
- Pregnancy & Childbirth (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Toxicology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gynecology & Obstetrics (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Procedimiento para el enriquecimiento de proteína de tejidos que presenta a) una porción proteínica de 94más menos 3%; un contenido de hidratos de carbono de 5,4 má menos 2,2%, y de ellos hexosas 3,0 más menos 1%, hexosamina 1,2 más menos 0,5% mucosa 0,2 más menos 0,2%, ácido neurámico 1,0 más menos 0,5%; b) un coeficiente de sedimentación ***(ver fórmula I) De 3,5 más menos S; c) un punto isoeléctrico de 4,9 más menos 0,3, medido con placas de gel de poliacrilamida, y de 4,5 más menos 0,3, medido en una columna de enfoque eléctrico; d) una movilidad electroforética en la gama de las globulinas alpha sub2 y beta sub1; e) un coeficiente de extinción ***(ver fórmula II) cm (278 nm) de 11,9 más menos 1,0.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2640387A DE2640387C3 (de) | 1976-09-08 | 1976-09-08 | Gewebespezifisches Protein und Verfahren zu dessen Herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES462069A1 true ES462069A1 (es) | 1978-06-01 |
Family
ID=5987430
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES462069A Expired ES462069A1 (es) | 1976-09-08 | 1977-09-02 | Procedimiento para el enriquecimiento de proteina de teji- dos. |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US4254021A (es) |
| JP (1) | JPS5334913A (es) |
| AT (1) | AT365929B (es) |
| AU (1) | AU517607B2 (es) |
| BE (1) | BE858521A (es) |
| CA (1) | CA1092971A (es) |
| DE (1) | DE2640387C3 (es) |
| DK (1) | DK397677A (es) |
| ES (1) | ES462069A1 (es) |
| FI (1) | FI61192C (es) |
| FR (1) | FR2364225A1 (es) |
| GB (1) | GB1586240A (es) |
| IE (1) | IE45678B1 (es) |
| IL (1) | IL52899A (es) |
| IT (1) | IT1084741B (es) |
| LU (1) | LU78084A1 (es) |
| NL (1) | NL7709740A (es) |
| NO (1) | NO773093L (es) |
| NZ (1) | NZ185106A (es) |
| SE (1) | SE7710085L (es) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2718325C2 (de) * | 1977-04-25 | 1986-09-25 | Behringwerke Ag, 3550 Marburg | Leucinreiches 3,1-S-α↓2↓-Glykoprotein sowie dessen Verwendung |
| DE2720704C2 (de) * | 1977-05-07 | 1986-09-25 | Behringwerke Ag, 3550 Marburg | Neues Glycoprotein, Verfahren zu seiner Herstellung und seine Verwendung |
| DE2842467A1 (de) * | 1978-09-29 | 1980-04-10 | Behringwerke Ag | Neues ubiquitaeres gewebsprotein pp tief 8 |
| DE2854759A1 (de) * | 1978-12-19 | 1980-07-10 | Behringwerke Ag | Neues plazentaspezifisches gewebsprotein pp tief 10 |
| DE2952792A1 (de) * | 1979-12-31 | 1981-07-02 | Behringwerke Ag, 3550 Marburg | Neues protein (pp(pfeil abwaerts)15(pfeil abwaerts)) mit immunsuppressiver wirkung |
| DE3013724A1 (de) * | 1980-04-10 | 1981-10-15 | Behringwerke Ag, 3550 Marburg | Neues protein pp (pfeil abwaerts)9(pfeil abwaerts), verfahren zu seiner anreicherung und gewinnung sowieseine verwendung |
| DE3109629A1 (de) * | 1981-03-13 | 1982-09-23 | Behringwerke Ag, 3550 Marburg | "neues protein (pp(pfeil abwaerts)1(pfeil abwaerts)(pfeil abwaerts)6(pfeil abwaerts)), verfahren zu seiner anreicherung und gewinnung sowie seine verwendung" |
| DE3228503A1 (de) * | 1982-07-30 | 1984-02-02 | Behringwerke Ag, 3550 Marburg | Neues protein (pp(pfeil abwaerts)1(pfeil abwaerts)(pfeil abwaerts)7(pfeil abwaerts)), verfahren zu seiner anreicherung und gewinnung sowie seine verwendung |
| DE3230996A1 (de) * | 1982-08-20 | 1984-02-23 | Behringwerke Ag, 3550 Marburg | Neues protein (pp(pfeil abwaerts)1(pfeil abwaerts)(pfeil abwaerts)3(pfeil abwaerts)), verfahren zu seiner anreicherung und gewinnung sowie seine verwendung |
| DE3315000A1 (de) * | 1983-04-26 | 1984-10-31 | Behringwerke Ag, 3550 Marburg | Gewebeprotein pp(pfeil abwaerts)4(pfeil abwaerts), verfahren zu seiner gewinnung sowie seine verwendung |
| DE3334405A1 (de) * | 1983-09-23 | 1985-04-04 | Behringwerke Ag, 3550 Marburg | Membranassoziierte proteine (mp(pfeil abwaerts)2(pfeil abwaerts)), verfahren zu ihrer gewinnung sowie ihre verwendung |
| DE3404563A1 (de) * | 1984-02-09 | 1985-08-14 | Behringwerke Ag, 3550 Marburg | Gewebeprotein pp(pfeil abwaerts)1(pfeil abwaerts)(pfeil abwaerts)9(pfeil abwaerts), verfahren zu seiner gewinnung sowie seine verwendung |
| DE3418888A1 (de) * | 1984-05-21 | 1985-11-21 | Behringwerke Ag, 3550 Marburg | Gewebeprotein pp(pfeil abwaerts)1(pfeil abwaerts)(pfeil abwaerts)8(pfeil abwaerts), verfahren zu seiner gewinnung sowie seine verwendung |
| CA1265446A (en) * | 1985-09-30 | 1990-02-06 | Masahiro Maki | Anticoagulating substance, process for preparing same and anticoagulant comprising same as an effective component |
| JPH0689014B2 (ja) * | 1986-01-21 | 1994-11-09 | 興和株式会社 | トロンビン結合性物質およびその製法 |
| RU94022543A (ru) * | 1994-06-10 | 1996-05-20 | АОЗТ "Научно-практический центр медикобиологических проблем" | Основа лекарственного средства и способ ее изготовления |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3409605A (en) * | 1965-06-15 | 1968-11-05 | American Cyanamid Co | Concentration and purification of growth factor-placental origin (human) |
| US3497492A (en) * | 1968-04-02 | 1970-02-24 | American Cyanamid Co | Preparation of placental albumin |
| US3931399A (en) * | 1970-12-22 | 1976-01-06 | Behringwerke Aktiengesellschaft | Process for isolating a fibrin-stabilizing factor |
| US3904751A (en) * | 1970-12-22 | 1975-09-09 | Behringwerke Ag | Process for isolating a fibrin stabilizing factor from human placenta |
| US4191533A (en) * | 1971-09-29 | 1980-03-04 | Behringwerke Aktiengesellschaft | Pregnancy-specific β1 -glycoprotein and process for isolating it |
| DE2221261A1 (de) * | 1972-04-29 | 1973-11-15 | Behringwerke Ag | Ap-glykoproteine und verfahren zu ihrer isolierung |
| FR2215944A1 (en) * | 1973-02-01 | 1974-08-30 | Bellon Labor Sa Roger | Extracts of human placenta - free of proteases, and contg. histaminase, kininases and monoamine-oxidases for treating allergies |
| DE2353973C3 (de) * | 1973-10-27 | 1979-10-04 | Behringwerke Ag, 3550 Marburg | Steroid-bindendes Globulin und Verfahren zu dessen Herstellung |
| FR2261755A1 (en) * | 1974-02-25 | 1975-09-19 | Thomas Andre | Glyco protein and mucopolysaccharides extraction - from naturally occuring materials fr use in cosmetics |
| US3910822A (en) * | 1974-03-14 | 1975-10-07 | Us Health | Isolation of glucocerebrosidase from human placental tissue |
| DE2616984C3 (de) * | 1976-04-17 | 1981-10-29 | Behringwerke Ag, 3550 Marburg | Verfahren zur Isolierung und Reinigung eines plazentenspezifischen Glycoproteins |
-
1976
- 1976-09-08 DE DE2640387A patent/DE2640387C3/de not_active Expired
-
1977
- 1977-09-02 ES ES462069A patent/ES462069A1/es not_active Expired
- 1977-09-05 NL NL7709740A patent/NL7709740A/xx not_active Application Discontinuation
- 1977-09-06 LU LU78084A patent/LU78084A1/xx unknown
- 1977-09-06 IL IL52899A patent/IL52899A/xx unknown
- 1977-09-06 IT IT27296/77A patent/IT1084741B/it active
- 1977-09-06 NZ NZ185106A patent/NZ185106A/xx unknown
- 1977-09-06 FI FI772641A patent/FI61192C/fi not_active IP Right Cessation
- 1977-09-07 AT AT0643777A patent/AT365929B/de not_active IP Right Cessation
- 1977-09-07 AU AU28621/77A patent/AU517607B2/en not_active Expired
- 1977-09-07 CA CA286,249A patent/CA1092971A/en not_active Expired
- 1977-09-07 DK DK397677A patent/DK397677A/da not_active Application Discontinuation
- 1977-09-07 NO NO773093A patent/NO773093L/no unknown
- 1977-09-07 IE IE1855/77A patent/IE45678B1/en unknown
- 1977-09-08 FR FR7727245A patent/FR2364225A1/fr active Granted
- 1977-09-08 SE SE7710085A patent/SE7710085L/xx not_active Application Discontinuation
- 1977-09-08 GB GB37521/77A patent/GB1586240A/en not_active Expired
- 1977-09-08 BE BE180770A patent/BE858521A/xx unknown
- 1977-09-08 JP JP10870577A patent/JPS5334913A/ja active Pending
-
1979
- 1979-08-21 US US06/068,459 patent/US4254021A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DK397677A (da) | 1978-03-09 |
| DE2640387A1 (de) | 1978-03-16 |
| FI772641A (fi) | 1978-03-09 |
| BE858521A (fr) | 1978-03-08 |
| FR2364225A1 (fr) | 1978-04-07 |
| CA1092971A (en) | 1981-01-06 |
| GB1586240A (en) | 1981-03-18 |
| IT1084741B (it) | 1985-05-28 |
| AU517607B2 (en) | 1981-08-13 |
| IL52899A0 (en) | 1977-11-30 |
| NO773093L (no) | 1978-03-09 |
| JPS5334913A (en) | 1978-03-31 |
| SE7710085L (sv) | 1978-03-09 |
| DE2640387C3 (de) | 1981-01-22 |
| NZ185106A (en) | 1980-05-27 |
| IL52899A (en) | 1980-09-16 |
| FR2364225B1 (es) | 1982-11-19 |
| FI61192B (fi) | 1982-02-26 |
| AT365929B (de) | 1982-02-25 |
| IE45678B1 (en) | 1982-10-20 |
| AU2862177A (en) | 1979-03-15 |
| ATA643777A (de) | 1981-07-15 |
| IE45678L (en) | 1978-03-08 |
| NL7709740A (nl) | 1978-03-10 |
| FI61192C (fi) | 1982-06-10 |
| LU78084A1 (es) | 1978-06-01 |
| US4254021A (en) | 1981-03-03 |
| DE2640387B2 (de) | 1980-05-22 |
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