ES461913A1 - Un procedimiento para la preparacion de derivados polimeti- lenicos alfa-omega-disustituidos. - Google Patents

Un procedimiento para la preparacion de derivados polimeti- lenicos alfa-omega-disustituidos.

Info

Publication number
ES461913A1
ES461913A1 ES461913A ES461913A ES461913A1 ES 461913 A1 ES461913 A1 ES 461913A1 ES 461913 A ES461913 A ES 461913A ES 461913 A ES461913 A ES 461913A ES 461913 A1 ES461913 A1 ES 461913A1
Authority
ES
Spain
Prior art keywords
alkanes
hypolipidaemic
certain
substituted phenoxy
phenoxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES461913A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Publication of ES461913A1 publication Critical patent/ES461913A1/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C321/00Thiols, sulfides, hydropolysulfides or polysulfides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/20Unsaturated compounds containing keto groups bound to acyclic carbon atoms
    • C07C49/255Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing ether groups, groups, groups, or groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/84Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)

Abstract

Un procedimiento para la preparación de derivados polimetilénicos alfa-omega-disustituidos de fórmula (III): **(Fórmula)** donde R es un grupo ácido carboxílico, o una sal farmacéuticamente aceptable, un éster, una amida o una hidrazida del mismo; un grupo alquilo, opcionalmente sustituido con uno o más grupos hidroxilo; un grupo nitrilo, formilo, alquil (C1-6) o alquil (C1-6) carbonilo sustituido con carboxilo o carboxilo esterificado; q es cero o un número entero de 1 a 12; A y B representan oxígeno o azufre; y es un número entero de 7 a 25; R5 es hidrógeno, halógeno, alquilo C1-6 o alcoxi C1-6; R6 es hidrógeno, halógeno, alquilo C1-6, alcoxi C1-6, alcanoiloxi C1-6, nitro, amino, alquilamino C1-6, haloalquilo C1-6 o un grupo éster carboxílico; o R5 y R6, cuando se encuentran en átomos de carbono adyacente, representan juntos un grupo metilendioxi.
ES461913A 1976-08-27 1977-08-26 Un procedimiento para la preparacion de derivados polimeti- lenicos alfa-omega-disustituidos. Expired ES461913A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB35680/76A GB1551416A (en) 1976-08-27 1976-08-27 Long chain dioxy hypolipidaemics

Publications (1)

Publication Number Publication Date
ES461913A1 true ES461913A1 (es) 1978-12-01

Family

ID=10380393

Family Applications (2)

Application Number Title Priority Date Filing Date
ES461913A Expired ES461913A1 (es) 1976-08-27 1977-08-26 Un procedimiento para la preparacion de derivados polimeti- lenicos alfa-omega-disustituidos.
ES471635A Expired ES471635A1 (es) 1976-08-27 1978-07-11 Un procedimiento para la preparacion de derivados polimeti- lenicos

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES471635A Expired ES471635A1 (es) 1976-08-27 1978-07-11 Un procedimiento para la preparacion de derivados polimeti- lenicos

Country Status (17)

Country Link
US (1) US4154850A (es)
JP (1) JPS5328133A (es)
AT (1) AT359994B (es)
AU (1) AU507609B2 (es)
BE (1) BE857973A (es)
CH (1) CH629171A5 (es)
DE (1) DE2735394A1 (es)
DK (1) DK381477A (es)
ES (2) ES461913A1 (es)
FI (1) FI772512A (es)
FR (1) FR2362809A1 (es)
GB (1) GB1551416A (es)
IL (1) IL52622A (es)
NL (1) NL7709391A (es)
NZ (1) NZ184766A (es)
SE (1) SE7709379L (es)
ZA (1) ZA774602B (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4226801A (en) * 1979-06-25 1980-10-07 The United States Of America As Represented By The Secretary Of The Navy Terminated bis(3,4-dicyanophenoxy) alkanes
DE3326164A1 (de) * 1983-07-20 1985-01-31 Klinge Pharma GmbH, 8000 München Neue p-oxibenzoesaeure-derivate, sowie verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
CH671402A5 (es) * 1985-10-02 1989-08-31 Sandoz Ag
US4778925A (en) * 1985-12-30 1988-10-18 Klinge Pharma Gmbh New benzoic acid derivatives, as well as processes for their production and their use as pharmaceuticals
KR970006890B1 (ko) * 1987-10-20 1997-04-30 오스카 세이야꾸 가부시끼가이샤 페닐카르복시산 유도체 및 그 염
CA2104594C (en) * 1991-02-22 2004-05-11 Howard K. Shapiro Use of pharmaceutical compounds in the treatment of symptoms of disorders related to neurological diseases and etiologically related symptomology
DE4127800A1 (de) * 1991-08-22 1993-02-25 Klinge Co Chem Pharm Fab Neue p-oxibenzoesaeurederivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
US6396546B1 (en) 1994-05-20 2002-05-28 United Video Properties, Inc. Electronic television program guide schedule system and method
US6469753B1 (en) 1996-05-03 2002-10-22 Starsight Telecast, Inc. Information system
US6687906B1 (en) 1996-12-19 2004-02-03 Index Systems, Inc. EPG with advertising inserts
US6091044A (en) * 1998-12-03 2000-07-18 General Electric Company System for monitoring and controlling a welding/brazing operation
US9113107B2 (en) 2005-11-08 2015-08-18 Rovi Guides, Inc. Interactive advertising and program promotion in an interactive television system
US8832742B2 (en) 2006-10-06 2014-09-09 United Video Properties, Inc. Systems and methods for acquiring, categorizing and delivering media in interactive media guidance applications

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3716644A (en) * 1971-07-15 1973-02-13 American Cyanamid Co Hypolipidemic agents
IL45396A0 (en) * 1973-08-23 1974-11-29 Beecham Group Ltd Pharmaceutical compositions containing aryl aralkyl ether and thioether derivatives,certain such novel compounds and their preparation

Also Published As

Publication number Publication date
NZ184766A (en) 1979-10-25
IL52622A (en) 1981-01-30
BE857973A (fr) 1978-02-20
ATA613777A (de) 1980-05-15
ES471635A1 (es) 1979-02-01
GB1551416A (en) 1979-08-30
DE2735394A1 (de) 1978-03-02
IL52622A0 (en) 1977-10-31
FI772512A (fi) 1978-02-28
AU2814377A (en) 1979-03-01
AT359994B (de) 1980-12-10
FR2362809A1 (fr) 1978-03-24
ZA774602B (en) 1978-06-28
CH629171A5 (de) 1982-04-15
NL7709391A (nl) 1978-03-01
SE7709379L (sv) 1978-02-28
FR2362809B1 (es) 1980-11-07
JPS5328133A (en) 1978-03-16
DK381477A (da) 1978-02-28
US4154850A (en) 1979-05-15
AU507609B2 (en) 1980-02-21

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