ES460149A1 - Procedimiento de preparacion de la vincamina y de alcaloidesafines. - Google Patents

Procedimiento de preparacion de la vincamina y de alcaloidesafines.

Info

Publication number
ES460149A1
ES460149A1 ES460149A ES460149A ES460149A1 ES 460149 A1 ES460149 A1 ES 460149A1 ES 460149 A ES460149 A ES 460149A ES 460149 A ES460149 A ES 460149A ES 460149 A1 ES460149 A1 ES 460149A1
Authority
ES
Spain
Prior art keywords
reaction medium
oxygen
vincamine
mixture
image
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES460149A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Parcor SARL
Original Assignee
Parcor SARL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Parcor SARL filed Critical Parcor SARL
Publication of ES460149A1 publication Critical patent/ES460149A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D461/00—Heterocyclic compounds containing indolo [3,2,1-d,e] pyrido [3,2,1,j] [1,5]-naphthyridine ring systems, e.g. vincamine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Procedimiento de preparación de la vincamina y de alcaloides afines, caracterizado porque consiste en hacer reaccionar un compuesto de la fórmula: *** en la cual R es H o metoxi y X e Y son hidrógeno o representan conjuntamente un enlace suplementario de valencia entre los átomos de carbono a los cuales están unidos sobre un agente de formación de un carbanión en un medio de reacción, luego en enviar al medio de reacción oxígeno hasta rechazo de absorción, habiéndose añadido un reductor compatible con el oxígeno al medio de reacción antes del rechazo de absorción de oxígeno.
ES460149A 1976-07-13 1977-06-28 Procedimiento de preparacion de la vincamina y de alcaloidesafines. Expired ES460149A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7621432A FR2358412A1 (fr) 1976-07-13 1976-07-13 Procede de preparation de la vincamine et d'alcaloides apparentes

Publications (1)

Publication Number Publication Date
ES460149A1 true ES460149A1 (es) 1978-05-01

Family

ID=9175674

Family Applications (1)

Application Number Title Priority Date Filing Date
ES460149A Expired ES460149A1 (es) 1976-07-13 1977-06-28 Procedimiento de preparacion de la vincamina y de alcaloidesafines.

Country Status (17)

Country Link
US (1) US4145552A (es)
JP (1) JPS539799A (es)
AT (1) AT358190B (es)
AU (1) AU512158B2 (es)
BE (1) BE856723A (es)
CA (1) CA1084931A (es)
CH (1) CH628345A5 (es)
DE (1) DE2731480A1 (es)
ES (1) ES460149A1 (es)
FR (1) FR2358412A1 (es)
GB (1) GB1547039A (es)
IT (1) IT1081015B (es)
LU (1) LU77728A1 (es)
MX (1) MX4603E (es)
NL (1) NL7707257A (es)
NZ (1) NZ184566A (es)
ZA (1) ZA774020B (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4285949A (en) * 1978-12-11 1981-08-25 Omnichem Societe Anonyme Vincamine derivatives, their preparation and therapeutical use
IT1141285B (it) * 1980-04-17 1986-10-01 Inverni Della Beffa Spa Procedimento per la preparazione,di vincamina e di alcaloidi correlati
CH646166A5 (it) * 1980-09-30 1984-11-15 Linnea Sa Procedimento di sintesi parziale della vincamina e di alcaloidi indolici correlati.
HU185255B (en) * 1981-04-23 1984-12-28 Richter Gedeon Vegyeszet New process preparing compounds with eburnane skeleton by means of the oxidative transformation of tabersonine or dihydrotabersonine
CA1341261C (en) * 1987-01-22 2001-06-26 James P. Kutney Process for the synthesis of 3',4'-anhydrovinblastine, vinblastine and vincristine
AU1066888A (en) * 1987-01-22 1988-08-04 University Of British Columbia, The Process for the synthesis of vinblastine and vincristine
US20100221340A1 (en) * 2007-09-20 2010-09-02 University Of Rochester Method and compositions for treatment or prevention of inflammatory conditions
CN102558178B (zh) * 2012-01-09 2015-06-03 中国科学院昆明植物研究所 水甘草碱(tabersonine)衍生物及其药物组合物和制备方法与用途

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB640414A (en) * 1948-03-06 1950-07-19 Mavor & Coulson Ltd Improvements in props
FR2108947B1 (es) * 1970-10-22 1974-02-01 Men Jean Le
BE763730R (fr) * 1971-01-15 1971-08-02 Omnium Chimique Sa Procede de preparation de la vincamine naturelle a partir de latabersonine et derives indoliques
BE765427A (fr) * 1971-04-07 1971-08-30 Omnium Chimique Sa Procede de preparation de la vincine naturelle a partir de la (-) mehtoxy-11-tabersonine et derives indoliques nouveaux.
CH625239A5 (es) * 1974-08-09 1981-09-15 Buskine Sa

Also Published As

Publication number Publication date
BE856723A (fr) 1978-01-12
LU77728A1 (es) 1977-10-10
FR2358412B1 (es) 1979-03-30
AT358190B (de) 1980-08-25
DE2731480A1 (de) 1978-01-19
US4145552A (en) 1979-03-20
IT1081015B (it) 1985-05-16
JPS539799A (en) 1978-01-28
FR2358412A1 (fr) 1978-02-10
AU512158B2 (en) 1980-09-25
ATA500177A (de) 1980-01-15
AU2685577A (en) 1979-01-11
GB1547039A (en) 1979-06-06
NL7707257A (nl) 1978-01-17
MX4603E (es) 1982-06-29
ZA774020B (en) 1978-05-30
NZ184566A (en) 1980-03-05
CH628345A5 (fr) 1982-02-26
CA1084931A (fr) 1980-09-02

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