ES459903A1 - Quinoline derivatives - Google Patents
Quinoline derivativesInfo
- Publication number
- ES459903A1 ES459903A1 ES459903A ES459903A ES459903A1 ES 459903 A1 ES459903 A1 ES 459903A1 ES 459903 A ES459903 A ES 459903A ES 459903 A ES459903 A ES 459903A ES 459903 A1 ES459903 A1 ES 459903A1
- Authority
- ES
- Spain
- Prior art keywords
- compounds
- derivatives
- quinoline
- formula
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Psychiatry (AREA)
- Anesthesiology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
For the preparation of derivatives of quinoline of formula < IMAGE > with R and X according to Claim 1, the compounds of formula < IMAGE > are reduced. The compounds thus obtained in which R represents an alkenyl group can additionally be converted by catalytic hydrogenation to corresponding compounds in which R is an alkyl group. The derivatives of quinoline obtained are also used for the preparation of the addition salts of these derivatives with pharmaceutically acceptable acids. The new compounds are used especially for the treatment of pathological conditions caused by a disturbance of the operation of the serotoninergic systems.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7618555A FR2354771A1 (en) | 1976-06-18 | 1976-06-18 | ((QUINOLYL-4) -3 PROPYL-1) -4 PIPERIDINES, THEIR PREPARATION AND THEIR USE AS MEDICINAL PRODUCTS |
Publications (1)
Publication Number | Publication Date |
---|---|
ES459903A1 true ES459903A1 (en) | 1978-09-01 |
Family
ID=9174581
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES459903A Expired ES459903A1 (en) | 1976-06-18 | 1977-06-17 | Quinoline derivatives |
Country Status (20)
Country | Link |
---|---|
JP (1) | JPS52156933A (en) |
AR (1) | AR218452A1 (en) |
AT (1) | AT358589B (en) |
AU (1) | AU517786B2 (en) |
BE (1) | BE855790A (en) |
CA (1) | CA1106379A (en) |
CH (1) | CH625800A5 (en) |
DE (1) | DE2727144C3 (en) |
DK (1) | DK268777A (en) |
ES (1) | ES459903A1 (en) |
FR (1) | FR2354771A1 (en) |
GB (1) | GB1546537A (en) |
GR (1) | GR61990B (en) |
HU (1) | HU179758B (en) |
IL (1) | IL52329A (en) |
IT (1) | IT1082822B (en) |
LU (1) | LU77548A1 (en) |
MX (1) | MX4911E (en) |
NL (1) | NL7706614A (en) |
ZA (1) | ZA773643B (en) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2432518A2 (en) * | 1978-08-03 | 1980-02-29 | Pharmindustrie | ((QUINOLYL-4) -3 PROPYL-1) -4 PIPERIDINE DERIVATIVES FOR USE AS MEDICAMENTS |
FR2448530A1 (en) * | 1979-02-09 | 1980-09-05 | Pharmindustrie | Epimerisation of 3-vinyl-piperidine cpds. - by heating in protonic solvent |
GR69926B (en) * | 1978-03-23 | 1982-07-21 | Pharmindustrie | |
FR2471981A1 (en) * | 1979-12-21 | 1981-06-26 | Pharmindustrie | NOVEL DERIVATIVES OF (PIPERIDYL-4) -2 (QUINOLYL-4) -1 ETHANONE, INTERMEDIATE PRODUCTS AND PROCESSES FOR THEIR PREPARATION, AND THEIR USE AS MEDICAMENTS |
FR2477544A1 (en) * | 1980-03-07 | 1981-09-11 | Pharmindustrie | NOVEL CHLORO-3 QUINOLINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION, AND THEIR USE AS MEDICAMENTS |
FR2485014A1 (en) * | 1980-06-20 | 1981-12-24 | Pharmindustrie | NOVEL DERIVATIVES OF (QUINOLYL-2, -3 OR -4) -1 (PIPERIDYL OR PYRROLIDINYL-2 OR -3) -2 OR -3 ETHANONE OR PROPANONE, PROCESSES FOR THEIR PREPARATION, AND THEIR USE AS MEDICAMENTS |
FR2495470A1 (en) * | 1980-12-05 | 1982-06-11 | Pharmindustrie | NEW MEDICAMENTS BASED ON (QUINOLYL-4) -1 (PIPERIDYL-4) -2 ETHANOL OR (QUINOLYL-4) -1 (PIPERIDYL-4) -3 PROPANOL DERIVATIVES |
FR2842807A1 (en) | 2002-07-23 | 2004-01-30 | Aventis Pharma Sa | QUINOLYL PROPYL PIPERIDINE DERIVATIVES, PROCESS AND PREPARATION INTERMEDIATES AND COMPOSITIONS COMPRISING THE SAME |
US20090221644A1 (en) * | 2005-06-30 | 2009-09-03 | Stuart Edward Bradley | Gpcr Agonists |
-
1976
- 1976-06-18 FR FR7618555A patent/FR2354771A1/en active Granted
-
1977
- 1977-06-15 AT AT423277A patent/AT358589B/en not_active IP Right Cessation
- 1977-06-15 AR AR268067A patent/AR218452A1/en active
- 1977-06-15 CH CH737077A patent/CH625800A5/en not_active IP Right Cessation
- 1977-06-16 MX MX775818U patent/MX4911E/en unknown
- 1977-06-16 IL IL52329A patent/IL52329A/en unknown
- 1977-06-16 LU LU77548A patent/LU77548A1/en unknown
- 1977-06-16 DE DE2727144A patent/DE2727144C3/en not_active Expired
- 1977-06-16 NL NL7706614A patent/NL7706614A/en unknown
- 1977-06-17 IT IT68402/77A patent/IT1082822B/en active
- 1977-06-17 GB GB25358/77A patent/GB1546537A/en not_active Expired
- 1977-06-17 AU AU26188/77A patent/AU517786B2/en not_active Expired
- 1977-06-17 DK DK268777A patent/DK268777A/en not_active Application Discontinuation
- 1977-06-17 ES ES459903A patent/ES459903A1/en not_active Expired
- 1977-06-17 JP JP7195777A patent/JPS52156933A/en active Granted
- 1977-06-17 ZA ZA00773643A patent/ZA773643B/en unknown
- 1977-06-17 HU HU77MA2882A patent/HU179758B/en unknown
- 1977-06-17 CA CA280,812A patent/CA1106379A/en not_active Expired
- 1977-06-17 BE BE1008198A patent/BE855790A/en not_active IP Right Cessation
- 1977-06-18 GR GR53732A patent/GR61990B/en unknown
Also Published As
Publication number | Publication date |
---|---|
AU2618877A (en) | 1978-12-21 |
GB1546537A (en) | 1979-05-23 |
IL52329A (en) | 1980-10-26 |
FR2354771B1 (en) | 1982-01-08 |
GR61990B (en) | 1979-02-14 |
IT1082822B (en) | 1985-05-21 |
CA1106379A (en) | 1981-08-04 |
FR2354771A1 (en) | 1978-01-13 |
ZA773643B (en) | 1978-05-30 |
DE2727144B2 (en) | 1980-02-07 |
LU77548A1 (en) | 1979-04-09 |
MX4911E (en) | 1983-01-03 |
JPS6134404B2 (en) | 1986-08-07 |
BE855790A (en) | 1977-12-19 |
AU517786B2 (en) | 1981-08-27 |
CH625800A5 (en) | 1981-10-15 |
DK268777A (en) | 1977-12-19 |
DE2727144A1 (en) | 1977-12-29 |
DE2727144C3 (en) | 1980-10-02 |
AR218452A1 (en) | 1980-06-13 |
ATA423277A (en) | 1980-02-15 |
HU179758B (en) | 1982-12-28 |
AT358589B (en) | 1980-09-25 |
NL7706614A (en) | 1977-12-20 |
IL52329A0 (en) | 1977-08-31 |
JPS52156933A (en) | 1977-12-27 |
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