FR2354771A1 - ((QUINOLYL-4) -3 PROPYL-1) -4 PIPERIDINES, THEIR PREPARATION AND THEIR USE AS MEDICINAL PRODUCTS - Google Patents

((QUINOLYL-4) -3 PROPYL-1) -4 PIPERIDINES, THEIR PREPARATION AND THEIR USE AS MEDICINAL PRODUCTS

Info

Publication number
FR2354771A1
FR2354771A1 FR7618555A FR7618555A FR2354771A1 FR 2354771 A1 FR2354771 A1 FR 2354771A1 FR 7618555 A FR7618555 A FR 7618555A FR 7618555 A FR7618555 A FR 7618555A FR 2354771 A1 FR2354771 A1 FR 2354771A1
Authority
FR
France
Prior art keywords
piperidines
quinolyl
propyl
preparation
medicinal products
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7618555A
Other languages
French (fr)
Other versions
FR2354771B1 (en
Inventor
Alain Champseix
Claude Gueremy
Gerard Le Fur
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MAR PHA ETU EXPL MARQUES
Original Assignee
MAR PHA ETU EXPL MARQUES
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by MAR PHA ETU EXPL MARQUES filed Critical MAR PHA ETU EXPL MARQUES
Priority to FR7618555A priority Critical patent/FR2354771A1/en
Priority to AT423277A priority patent/AT358589B/en
Priority to CH737077A priority patent/CH625800A5/en
Priority to AR268067A priority patent/AR218452A1/en
Priority to DE2727144A priority patent/DE2727144C3/en
Priority to IL52329A priority patent/IL52329A/en
Priority to LU77548A priority patent/LU77548A1/en
Priority to NL7706614A priority patent/NL7706614A/en
Priority to MX775818U priority patent/MX4911E/en
Priority to CA280,812A priority patent/CA1106379A/en
Priority to ZA00773643A priority patent/ZA773643B/en
Priority to ES459903A priority patent/ES459903A1/en
Priority to IT68402/77A priority patent/IT1082822B/en
Priority to AU26188/77A priority patent/AU517786B2/en
Priority to PT66682A priority patent/PT66682B/en
Priority to HU77MA2882A priority patent/HU179758B/en
Priority to BE1008198A priority patent/BE855790A/en
Priority to DK268777A priority patent/DK268777A/en
Priority to JP7195777A priority patent/JPS52156933A/en
Priority to GB25358/77A priority patent/GB1546537A/en
Priority to GR53732A priority patent/GR61990B/en
Publication of FR2354771A1 publication Critical patent/FR2354771A1/en
Priority to US05/968,718 priority patent/US4237139A/en
Priority to CA362,714A priority patent/CA1116089A/en
Priority to US06/210,084 priority patent/US4299835A/en
Application granted granted Critical
Publication of FR2354771B1 publication Critical patent/FR2354771B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Les composés de formule :Compounds of formula:

FR7618555A 1976-06-18 1976-06-18 ((QUINOLYL-4) -3 PROPYL-1) -4 PIPERIDINES, THEIR PREPARATION AND THEIR USE AS MEDICINAL PRODUCTS Granted FR2354771A1 (en)

Priority Applications (24)

Application Number Priority Date Filing Date Title
FR7618555A FR2354771A1 (en) 1976-06-18 1976-06-18 ((QUINOLYL-4) -3 PROPYL-1) -4 PIPERIDINES, THEIR PREPARATION AND THEIR USE AS MEDICINAL PRODUCTS
AT423277A AT358589B (en) 1976-06-18 1977-06-15 METHOD FOR PRODUCING CHINOLINE DERIVATIVES AND THEIR ACID ADDITION SALTS
CH737077A CH625800A5 (en) 1976-06-18 1977-06-15 Process for the preparation of derivatives of quinoline
AR268067A AR218452A1 (en) 1976-06-18 1977-06-15 PROCEDURE FOR OBTAINING DERIVATIVES OF 4- (3- (4-PIPERIDIL) -PROPIL) -QUINOLEIN AND ITS SALTS
IL52329A IL52329A (en) 1976-06-18 1977-06-16 Pharmaceutical compostitions containing (3-(4-quinolyl)-1-propyl)-4-piperidines
LU77548A LU77548A1 (en) 1976-06-18 1977-06-16 ((QUINOLYL-4) -3 PROPYL-1) -4PIPERIDINES, THEIR PREPARATION AND THEIR USE AS MEDICINAL PRODUCTS
NL7706614A NL7706614A (en) 1976-06-18 1977-06-16 METHOD FOR PREPARING A MEDICINAL PRODUCT, SUCHED MEDICINAL PRODUCT AND METHOD FOR PREPARING MEDICINAL COMPOUNDS.
MX775818U MX4911E (en) 1976-06-18 1977-06-16 PROCEDURE FOR PREPARING QUINOLEIN DERIVATIVES
DE2727144A DE2727144C3 (en) 1976-06-18 1977-06-16 Use of certain quinoline derivatives
JP7195777A JPS52156933A (en) 1976-06-18 1977-06-17 Medical composition containing *33*44quiolyl**iipropyl**44 piperidine
ES459903A ES459903A1 (en) 1976-06-18 1977-06-17 Quinoline derivatives
IT68402/77A IT1082822B (en) 1976-06-18 1977-06-17 CHINOLIL 4 3 PROPIL 1 4 PIPERIDINE THEIR PREPARATION AND USE
CA280,812A CA1106379A (en) 1976-06-18 1977-06-17 Preparation and pharmacological uses of [(quinolyl- 4)-3-propyl-1]-4-piperidines
PT66682A PT66682B (en) 1976-06-18 1977-06-17 / (QUINOLYL-4) -PROPYL-1 / -4 PIPERIDINES LEUR PREPARATION ET LEUR UTILIZATION COMME MEDICAMENTS / (QUINOLYL-4) -PROPYL / -4 PIPERIDINES LEUR PREPARATION ET LEUR UTILIZATION COMME MEDICAMENTS
HU77MA2882A HU179758B (en) 1976-06-18 1977-06-17 Process for preparing pharmaceutical preparations containing quinolyl-propyl-piperidine derivatives as active substances
BE1008198A BE855790A (en) 1976-06-18 1977-06-17 (QUINOLYL-4) -3 PROPYL-1) -4 PIPERIDINES, THEIR PREPARATION AND THEIR USE AS MEDICINAL PRODUCTS
DK268777A DK268777A (en) 1976-06-18 1977-06-17 (3- (QUINOLYL-4) -1-PROPYL) -4-PIPERIDINES THEIR PREPARATION AND THEIR USE AS MEDICINES
ZA00773643A ZA773643B (en) 1976-06-18 1977-06-17 (3-(4-quinolyl)-1-propyl)-4-piperidines their preparation and their use as medicines
GB25358/77A GB1546537A (en) 1976-06-18 1977-06-17 Quinoline derivatives
AU26188/77A AU517786B2 (en) 1976-06-18 1977-06-17 3 (4-QUINOLY) l-PROPYL]-4-PIPERIDINES
GR53732A GR61990B (en) 1976-06-18 1977-06-18 Preparation process of ((quinolyl-4)-3propyl-1)-4piperidines
US05/968,718 US4237139A (en) 1976-06-18 1978-12-12 4-(3-(4-Quinolyl)propyl)piperidines, their preparation and their use as medicines
CA362,714A CA1116089A (en) 1976-06-18 1980-10-17 Pharmaceutical compositions containing quinoline derivatives
US06/210,084 US4299835A (en) 1976-06-18 1980-11-24 4-[(3-(4-Quinolyl)propyl])piperidines, their preparation and their use as medicines

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7618555A FR2354771A1 (en) 1976-06-18 1976-06-18 ((QUINOLYL-4) -3 PROPYL-1) -4 PIPERIDINES, THEIR PREPARATION AND THEIR USE AS MEDICINAL PRODUCTS

Publications (2)

Publication Number Publication Date
FR2354771A1 true FR2354771A1 (en) 1978-01-13
FR2354771B1 FR2354771B1 (en) 1982-01-08

Family

ID=9174581

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7618555A Granted FR2354771A1 (en) 1976-06-18 1976-06-18 ((QUINOLYL-4) -3 PROPYL-1) -4 PIPERIDINES, THEIR PREPARATION AND THEIR USE AS MEDICINAL PRODUCTS

Country Status (20)

Country Link
JP (1) JPS52156933A (en)
AR (1) AR218452A1 (en)
AT (1) AT358589B (en)
AU (1) AU517786B2 (en)
BE (1) BE855790A (en)
CA (1) CA1106379A (en)
CH (1) CH625800A5 (en)
DE (1) DE2727144C3 (en)
DK (1) DK268777A (en)
ES (1) ES459903A1 (en)
FR (1) FR2354771A1 (en)
GB (1) GB1546537A (en)
GR (1) GR61990B (en)
HU (1) HU179758B (en)
IL (1) IL52329A (en)
IT (1) IT1082822B (en)
LU (1) LU77548A1 (en)
MX (1) MX4911E (en)
NL (1) NL7706614A (en)
ZA (1) ZA773643B (en)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0005654A1 (en) * 1978-03-23 1979-11-28 Pharmuka Laboratoires Process for the isomerization of 3-vinyl-piperidine derivatives
FR2432518A2 (en) * 1978-08-03 1980-02-29 Pharmindustrie ((QUINOLYL-4) -3 PROPYL-1) -4 PIPERIDINE DERIVATIVES FOR USE AS MEDICAMENTS
FR2448530A1 (en) * 1979-02-09 1980-09-05 Pharmindustrie Epimerisation of 3-vinyl-piperidine cpds. - by heating in protonic solvent
FR2471981A1 (en) * 1979-12-21 1981-06-26 Pharmindustrie NOVEL DERIVATIVES OF (PIPERIDYL-4) -2 (QUINOLYL-4) -1 ETHANONE, INTERMEDIATE PRODUCTS AND PROCESSES FOR THEIR PREPARATION, AND THEIR USE AS MEDICAMENTS
FR2477544A1 (en) * 1980-03-07 1981-09-11 Pharmindustrie NOVEL CHLORO-3 QUINOLINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION, AND THEIR USE AS MEDICAMENTS
FR2485014A1 (en) * 1980-06-20 1981-12-24 Pharmindustrie NOVEL DERIVATIVES OF (QUINOLYL-2, -3 OR -4) -1 (PIPERIDYL OR PYRROLIDINYL-2 OR -3) -2 OR -3 ETHANONE OR PROPANONE, PROCESSES FOR THEIR PREPARATION, AND THEIR USE AS MEDICAMENTS
US6806277B2 (en) 2002-07-23 2004-10-19 Aventis, Pharma S.A. Quinolylpropylpiperidine derivatives, preparation process and intermediates, and compositions including them

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2495470A1 (en) * 1980-12-05 1982-06-11 Pharmindustrie NEW MEDICAMENTS BASED ON (QUINOLYL-4) -1 (PIPERIDYL-4) -2 ETHANOL OR (QUINOLYL-4) -1 (PIPERIDYL-4) -3 PROPANOL DERIVATIVES
EP1907384A2 (en) * 2005-06-30 2008-04-09 Prosidion Limited Gpcr agonists

Cited By (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0005654A1 (en) * 1978-03-23 1979-11-28 Pharmuka Laboratoires Process for the isomerization of 3-vinyl-piperidine derivatives
US4238612A (en) * 1978-03-23 1980-12-09 Pharmindustrie Process for the isomerization of derivatives of 3-vinyl-piperidine
FR2432518A2 (en) * 1978-08-03 1980-02-29 Pharmindustrie ((QUINOLYL-4) -3 PROPYL-1) -4 PIPERIDINE DERIVATIVES FOR USE AS MEDICAMENTS
EP0008962A1 (en) * 1978-08-03 1980-03-19 Pharmuka Laboratoires 4-(4-Quinolylpropyl)piperidine derivatives and pharmaceuticals containing them
FR2448530A1 (en) * 1979-02-09 1980-09-05 Pharmindustrie Epimerisation of 3-vinyl-piperidine cpds. - by heating in protonic solvent
EP0031753A1 (en) * 1979-12-21 1981-07-08 Pharmuka Laboratoires 2-(4-Piperidyl)-1-(4-quinolyl)-ethanone derivatives, intermediates in and process for their preparation, and their use as medicines
FR2471981A1 (en) * 1979-12-21 1981-06-26 Pharmindustrie NOVEL DERIVATIVES OF (PIPERIDYL-4) -2 (QUINOLYL-4) -1 ETHANONE, INTERMEDIATE PRODUCTS AND PROCESSES FOR THEIR PREPARATION, AND THEIR USE AS MEDICAMENTS
US4433150A (en) * 1979-12-21 1984-02-21 Pharmindustrie 2-(4-Piperidyl)-1-(4-quinolyl)-ethanones and ethanes
FR2477544A1 (en) * 1980-03-07 1981-09-11 Pharmindustrie NOVEL CHLORO-3 QUINOLINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION, AND THEIR USE AS MEDICAMENTS
EP0035925A1 (en) * 1980-03-07 1981-09-16 Pharmuka Laboratoires 3-Chloroquinoline derivatives, processes for their preparation and medicaments containing them
US4493838A (en) * 1980-03-07 1985-01-15 Pharmindustrie Medicaments containing derivatives of 3-chloro-quinoline
FR2485014A1 (en) * 1980-06-20 1981-12-24 Pharmindustrie NOVEL DERIVATIVES OF (QUINOLYL-2, -3 OR -4) -1 (PIPERIDYL OR PYRROLIDINYL-2 OR -3) -2 OR -3 ETHANONE OR PROPANONE, PROCESSES FOR THEIR PREPARATION, AND THEIR USE AS MEDICAMENTS
EP0042781A1 (en) * 1980-06-20 1981-12-30 Pharmuka Laboratoires 1-(4 Quinolyl), 2- or 3- (2- or 3- piperidyl or pyrrolidinyl) ethanone or propanone, process for their preparation and their use as medicaments
US6806277B2 (en) 2002-07-23 2004-10-19 Aventis, Pharma S.A. Quinolylpropylpiperidine derivatives, preparation process and intermediates, and compositions including them

Also Published As

Publication number Publication date
BE855790A (en) 1977-12-19
CA1106379A (en) 1981-08-04
IL52329A0 (en) 1977-08-31
DK268777A (en) 1977-12-19
IL52329A (en) 1980-10-26
ATA423277A (en) 1980-02-15
DE2727144A1 (en) 1977-12-29
CH625800A5 (en) 1981-10-15
DE2727144C3 (en) 1980-10-02
JPS6134404B2 (en) 1986-08-07
NL7706614A (en) 1977-12-20
FR2354771B1 (en) 1982-01-08
LU77548A1 (en) 1979-04-09
AU517786B2 (en) 1981-08-27
HU179758B (en) 1982-12-28
MX4911E (en) 1983-01-03
AU2618877A (en) 1978-12-21
AR218452A1 (en) 1980-06-13
ZA773643B (en) 1978-05-30
DE2727144B2 (en) 1980-02-07
GR61990B (en) 1979-02-14
ES459903A1 (en) 1978-09-01
AT358589B (en) 1980-09-25
IT1082822B (en) 1985-05-21
JPS52156933A (en) 1977-12-27
GB1546537A (en) 1979-05-23

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ST Notification of lapse