ES458764A1 - Procedimiento para la preparacion de un nuevo agente antiin-flamatorio. - Google Patents

Procedimiento para la preparacion de un nuevo agente antiin-flamatorio.

Info

Publication number
ES458764A1
ES458764A1 ES458764A ES458764A ES458764A1 ES 458764 A1 ES458764 A1 ES 458764A1 ES 458764 A ES458764 A ES 458764A ES 458764 A ES458764 A ES 458764A ES 458764 A1 ES458764 A1 ES 458764A1
Authority
ES
Spain
Prior art keywords
acetic acid
acid derivative
indolyl acetic
indolyl
azidobenzoyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES458764A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pierrel SpA
Original Assignee
Pierrel SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pierrel SpA filed Critical Pierrel SpA
Publication of ES458764A1 publication Critical patent/ES458764A1/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/58—1,2-Diazines; Hydrogenated 1,2-diazines
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
    • A01N47/10—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof
    • A01N47/22—O-Aryl or S-Aryl esters thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/26—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an acyl radical attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dentistry (AREA)
  • Pest Control & Pesticides (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Plant Pathology (AREA)
  • Veterinary Medicine (AREA)
  • Agronomy & Crop Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Rheumatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Procedimiento para la preparación de un nuevo agente anti-inflamatorio, el ácido 1-(p-azidibenzoil)-5-metoxi-2-metil-3-indolilacético y sus sales farmacéuticamente aceptable, caracterizado por someter ácido 1-(p-aminibenzoil)-5-metoxi-2-metil-3- indolilacético a diazotización seguido de tratamiento con ácido hidrazóico.
ES458764A 1976-05-19 1977-05-13 Procedimiento para la preparacion de un nuevo agente antiin-flamatorio. Expired ES458764A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB20596/76A GB1531546A (en) 1976-05-19 1976-05-19 Anti-inflammatory indole derivative

Publications (1)

Publication Number Publication Date
ES458764A1 true ES458764A1 (es) 1978-03-01

Family

ID=10148550

Family Applications (1)

Application Number Title Priority Date Filing Date
ES458764A Expired ES458764A1 (es) 1976-05-19 1977-05-13 Procedimiento para la preparacion de un nuevo agente antiin-flamatorio.

Country Status (21)

Country Link
US (1) US4181740A (es)
JP (1) JPS6054957B2 (es)
AT (2) AT353785B (es)
AU (1) AU513192B2 (es)
BE (1) BE854827A (es)
CA (1) CA1072545A (es)
CH (2) CH620429A5 (es)
DE (1) DE2722399A1 (es)
DK (1) DK215177A (es)
ES (1) ES458764A1 (es)
FR (1) FR2351960A1 (es)
GB (1) GB1531546A (es)
GR (1) GR63225B (es)
IE (1) IE45061B1 (es)
IL (1) IL51950A (es)
IN (1) IN145784B (es)
LU (1) LU77366A1 (es)
NL (1) NL7704202A (es)
PH (1) PH14095A (es)
YU (1) YU39997B (es)
ZA (1) ZA772468B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59204172A (ja) * 1983-04-28 1984-11-19 Kowa Co アセメタシンの製造法
DE3602670A1 (de) * 1986-01-29 1987-07-30 Speck Ulrich Verwendung von n-acetylglucosamin zur therapie degenerativer gelenkprozesse und verwandter erkrankungen
KR940007001A (ko) * 1992-09-16 1994-04-26 최승주 새로운 n-신나모일-2-메틸-5-메톡시-3-인돌 아세트산 에스테르, 그 제조방법 및 이를 함유하는 약학적 제제
CA2527114A1 (en) * 2003-05-30 2004-12-16 Microbia, Inc. Methods for the protection of memory and cognition

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD70880A (es) *
FR1534460A (fr) * 1966-08-25 1968-07-26 Merck & Co Inc Procédé de fabrication d'acides alpha-(1-aroyl-3-indolyl)-alcanoïques
NL6804994A (es) * 1967-04-11 1968-10-14
DE2234651C3 (de) * 1972-07-14 1978-11-09 Troponwerke Gmbh & Co Kg, 5000 Koeln Eckige Klammer auf l-(p-Chlorbenzoyl)-5-methoxy-2-methyl-3-indol] -acetoxj essigsaure, ihre Salze mit Basen, Verfahren zu ihrer Herstellung sowie pharmakologische Zubereitungen

Also Published As

Publication number Publication date
FR2351960A1 (fr) 1977-12-16
DK215177A (da) 1977-11-20
LU77366A1 (es) 1977-08-29
AT353785B (de) 1979-12-10
US4181740A (en) 1980-01-01
IL51950A (en) 1980-09-16
YU123177A (en) 1983-01-21
NL7704202A (nl) 1977-11-22
ZA772468B (en) 1978-03-29
IE45061L (en) 1977-11-19
CA1072545A (en) 1980-02-26
CH620429A5 (es) 1980-11-28
CH625507A5 (es) 1981-09-30
IN145784B (es) 1978-12-16
JPS6054957B2 (ja) 1985-12-03
AU2452577A (en) 1978-10-26
AU513192B2 (en) 1980-11-20
BE854827A (fr) 1977-09-16
FR2351960B1 (es) 1980-03-07
ATA358077A (de) 1979-05-15
AT358077B (de) 1979-05-15
GR63225B (en) 1979-10-10
PH14095A (en) 1981-02-10
DE2722399A1 (de) 1977-12-01
ATA171278A (de) 1980-01-15
GB1531546A (en) 1978-11-08
YU39997B (en) 1985-06-30
IE45061B1 (en) 1982-06-16
JPS537666A (en) 1978-01-24

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19971001