ES458724A1 - Procedimiento para la produccion de derivados de 3-amino-2- hidroxi-propoxifenilo. - Google Patents
Procedimiento para la produccion de derivados de 3-amino-2- hidroxi-propoxifenilo.Info
- Publication number
- ES458724A1 ES458724A1 ES77458724A ES458724A ES458724A1 ES 458724 A1 ES458724 A1 ES 458724A1 ES 77458724 A ES77458724 A ES 77458724A ES 458724 A ES458724 A ES 458724A ES 458724 A1 ES458724 A1 ES 458724A1
- Authority
- ES
- Spain
- Prior art keywords
- carbon atoms
- alkyl
- substituted
- halogen
- hydrogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- QNXSIUBBGPHDDE-UHFFFAOYSA-N indan-1-one Chemical class C1=CC=C2C(=O)CCC2=C1 QNXSIUBBGPHDDE-UHFFFAOYSA-N 0.000 title 1
- 125000003003 spiro group Chemical group 0.000 title 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 12
- 125000000217 alkyl group Chemical group 0.000 abstract 6
- 229910052736 halogen Chemical group 0.000 abstract 3
- 150000002367 halogens Chemical group 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 3
- -1 2,2,6,6-tetramethylpiperidinyl Chemical group 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 125000004450 alkenylene group Chemical group 0.000 abstract 1
- 125000004183 alkoxy alkyl group Chemical group 0.000 abstract 1
- 125000006350 alkyl thio alkyl group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 230000003276 anti-hypertensive effect Effects 0.000 abstract 1
- 239000002220 antihypertensive agent Substances 0.000 abstract 1
- 229940030600 antihypertensive agent Drugs 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000002431 hydrogen Chemical group 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 125000005359 phenoxyalkyl group Chemical group 0.000 abstract 1
- 125000003884 phenylalkyl group Chemical group 0.000 abstract 1
- 125000004193 piperazinyl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C217/28—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines
- C07C217/30—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring
- C07C217/38—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring being part of a condensed ring system containing rings other than six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/93—Spiro compounds
- C07C2603/94—Spiro compounds containing "free" spiro atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Urology & Nephrology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH606376A CH621330A5 (en, 2012) | 1976-05-14 | 1976-05-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES458724A1 true ES458724A1 (es) | 1978-08-01 |
Family
ID=4303639
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES77458724A Expired ES458724A1 (es) | 1976-05-14 | 1977-05-12 | Procedimiento para la produccion de derivados de 3-amino-2- hidroxi-propoxifenilo. |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US4322437A (en, 2012) |
| JP (1) | JPS52139051A (en, 2012) |
| AT (1) | AT362349B (en, 2012) |
| AU (1) | AU513066B2 (en, 2012) |
| BE (1) | BE854567A (en, 2012) |
| CA (1) | CA1095913A (en, 2012) |
| CH (1) | CH621330A5 (en, 2012) |
| CY (1) | CY1226A (en, 2012) |
| DE (1) | DE2719871A1 (en, 2012) |
| DK (1) | DK197677A (en, 2012) |
| ES (1) | ES458724A1 (en, 2012) |
| FI (1) | FI771427A7 (en, 2012) |
| FR (1) | FR2351091A1 (en, 2012) |
| GB (1) | GB1576034A (en, 2012) |
| HK (1) | HK35984A (en, 2012) |
| IE (1) | IE44950B1 (en, 2012) |
| IL (1) | IL52072A (en, 2012) |
| KE (1) | KE3405A (en, 2012) |
| NL (1) | NL7705128A (en, 2012) |
| NZ (1) | NZ184079A (en, 2012) |
| PH (1) | PH14176A (en, 2012) |
| PT (1) | PT66540B (en, 2012) |
| SE (1) | SE7705221L (en, 2012) |
| SG (1) | SG84983G (en, 2012) |
| SU (1) | SU634663A3 (en, 2012) |
| ZA (1) | ZA772873B (en, 2012) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2810869A1 (de) * | 1977-03-24 | 1978-09-28 | Sandoz Ag | 3-amino-2-hydroxypropoxy-derivate, ihre herstellung und verwendung |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2641152A (en) * | 1949-07-15 | 1953-06-09 | Herbert M Hise | Stringed musical instrument |
| GB1046001A (en) * | 1964-03-12 | 1966-10-19 | Ici Ltd | Propanolamine derivatives |
| US3839415A (en) * | 1965-10-22 | 1974-10-01 | Lilly Co Eli | 2-halo-1-(alkyl-1-(alkylamino)ethyl)vinyl benzoic acid esters and derivatives |
| US3641152A (en) * | 1968-09-23 | 1972-02-08 | Warner Lambert Pharmaceutical | 3 4-dihydronaphthalenoneoxy-2-hydroxy-propylamines |
| CH554314A (de) * | 1969-06-03 | 1974-09-30 | Sandoz Ag | Verfahren zur herstellung neuer fluorenone. |
| BE755071A (fr) * | 1969-09-17 | 1971-02-22 | Warner Lambert Pharmaceutical | Procede de resolution de la dl-5-/3-(terbutylamino)-2- hydroxy-propoxy/-3,4-dihydro-1(2h) naphtalenone |
-
1976
- 1976-05-14 CH CH606376A patent/CH621330A5/de not_active IP Right Cessation
-
1977
- 1977-05-04 DE DE19772719871 patent/DE2719871A1/de not_active Ceased
- 1977-05-05 SE SE7705221A patent/SE7705221L/xx not_active Application Discontinuation
- 1977-05-05 FI FI771427A patent/FI771427A7/fi not_active Application Discontinuation
- 1977-05-05 DK DK197677A patent/DK197677A/da not_active Application Discontinuation
- 1977-05-10 CY CY1226A patent/CY1226A/xx unknown
- 1977-05-10 NL NL7705128A patent/NL7705128A/xx not_active Application Discontinuation
- 1977-05-10 GB GB19551/77A patent/GB1576034A/en not_active Expired
- 1977-05-10 US US05/795,439 patent/US4322437A/en not_active Expired - Lifetime
- 1977-05-12 FR FR7714506A patent/FR2351091A1/fr active Granted
- 1977-05-12 IL IL52072A patent/IL52072A/xx unknown
- 1977-05-12 NZ NZ184079A patent/NZ184079A/xx unknown
- 1977-05-12 IE IE971/77A patent/IE44950B1/en unknown
- 1977-05-12 BE BE177524A patent/BE854567A/xx not_active IP Right Cessation
- 1977-05-12 PT PT66540A patent/PT66540B/pt unknown
- 1977-05-12 CA CA278,293A patent/CA1095913A/en not_active Expired
- 1977-05-12 ES ES77458724A patent/ES458724A1/es not_active Expired
- 1977-05-13 SU SU772480276A patent/SU634663A3/ru active
- 1977-05-13 ZA ZA00772873A patent/ZA772873B/xx unknown
- 1977-05-13 PH PH19769A patent/PH14176A/en unknown
- 1977-05-13 JP JP5449177A patent/JPS52139051A/ja active Pending
- 1977-05-13 AT AT343577A patent/AT362349B/de not_active IP Right Cessation
- 1977-05-13 AU AU25140/77A patent/AU513066B2/en not_active Expired
-
1983
- 1983-12-29 SG SG849/83A patent/SG84983G/en unknown
-
1984
- 1984-04-19 KE KE3405A patent/KE3405A/xx unknown
- 1984-04-26 HK HK359/84A patent/HK35984A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SG84983G (en) | 1985-01-11 |
| IE44950B1 (en) | 1982-05-19 |
| JPS52139051A (en) | 1977-11-19 |
| FI771427A7 (en, 2012) | 1977-11-15 |
| FR2351091B1 (en, 2012) | 1980-01-18 |
| SU634663A3 (ru) | 1978-11-25 |
| AT362349B (de) | 1981-05-11 |
| DK197677A (da) | 1977-11-15 |
| PT66540A (fr) | 1977-06-01 |
| US4322437A (en) | 1982-03-30 |
| CY1226A (en) | 1984-04-06 |
| BE854567A (fr) | 1977-11-14 |
| AU513066B2 (en) | 1980-11-13 |
| KE3405A (en) | 1985-02-01 |
| DE2719871A1 (de) | 1977-12-01 |
| GB1576034A (en) | 1980-10-01 |
| IL52072A (en) | 1980-10-26 |
| IL52072A0 (en) | 1977-07-31 |
| IE44950L (en) | 1977-11-14 |
| HK35984A (en) | 1984-05-04 |
| ZA772873B (en) | 1978-12-27 |
| PH14176A (en) | 1981-03-19 |
| NL7705128A (nl) | 1977-11-16 |
| CH621330A5 (en, 2012) | 1981-01-30 |
| SE7705221L (sv) | 1977-11-15 |
| NZ184079A (en) | 1978-09-25 |
| ATA343577A (de) | 1980-10-15 |
| PT66540B (fr) | 1979-10-22 |
| AU2514077A (en) | 1978-11-16 |
| FR2351091A1 (fr) | 1977-12-09 |
| CA1095913A (en) | 1981-02-17 |
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