ES458197A1 - Un procedimiento para la preparacion de nuevos peptidoglica-nos. - Google Patents

Un procedimiento para la preparacion de nuevos peptidoglica-nos.

Info

Publication number
ES458197A1
ES458197A1 ES458197A ES458197A ES458197A1 ES 458197 A1 ES458197 A1 ES 458197A1 ES 458197 A ES458197 A ES 458197A ES 458197 A ES458197 A ES 458197A ES 458197 A1 ES458197 A1 ES 458197A1
Authority
ES
Spain
Prior art keywords
compounds
immuniological
peptidoglycans
adjuvant
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES458197A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Syntex USA LLC
Original Assignee
Syntex USA LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/680,260 external-priority patent/US4082735A/en
Priority claimed from US05/680,618 external-priority patent/US4082736A/en
Application filed by Syntex USA LLC filed Critical Syntex USA LLC
Publication of ES458197A1 publication Critical patent/ES458197A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/001—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure
    • C07K9/005—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure containing within the molecule the substructure with m, n > 0 and m+n > 0, A, B, D, E being heteroatoms; X being a bond or a chain, e.g. muramylpeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)

Abstract

Un procedimiento para la preparación de nuevos peptidoglicanos de fórmula (I), donde cada uno de R y R1 son iguales o diferentes y están seleccionados del grupo formado por hidrógeno o un radical acilo de 1 a 22 átomos de carbono; *** Ver imagen
ES458197A 1976-04-26 1977-04-26 Un procedimiento para la preparacion de nuevos peptidoglica-nos. Expired ES458197A1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US05/680,260 US4082735A (en) 1976-04-26 1976-04-26 Novel immunological adjuvant compounds and methods of preparation thereof
US05/680,618 US4082736A (en) 1976-04-26 1976-04-26 Novel immunological adjuvant compounds and methods of preparation thereof
US77720477A 1977-03-14 1977-03-14

Publications (1)

Publication Number Publication Date
ES458197A1 true ES458197A1 (es) 1978-08-16

Family

ID=27418368

Family Applications (1)

Application Number Title Priority Date Filing Date
ES458197A Expired ES458197A1 (es) 1976-04-26 1977-04-26 Un procedimiento para la preparacion de nuevos peptidoglica-nos.

Country Status (8)

Country Link
JP (2) JPS52131526A (es)
CH (1) CH636887A5 (es)
DE (1) DE2718010A1 (es)
ES (1) ES458197A1 (es)
FR (1) FR2349600A1 (es)
GB (1) GB1571133A (es)
NL (1) NL7704555A (es)
SE (1) SE445924B (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2862107D1 (en) * 1977-12-02 1982-11-18 Takeda Chemical Industries Ltd Glucosamine-peptide derivatives and their pharmaceutical compositions
FR2442241A2 (fr) * 1978-03-20 1980-06-20 Anvar Nouveaux composes esters de muramyl-peptide, leur preparation et les compositions pharmaceutiques les contenant, notamment sous forme de liposomes
FR2420545A1 (fr) * 1978-03-20 1979-10-19 Anvar Nouveaux esters de l'acide n-acetyl-muramyl-aminoacyl-glutamique ou des derives de substitution de celui-ci a proprietes anti-infectieuses et/ou d'adjuvants immunologiques
US4335111A (en) * 1978-12-22 1982-06-15 Agence National De Valorisation De La Recherche (Anvar) Compounds associating peptidyl of aminoacyl residues to lipophilic groups and pharmaceutical compositions containing said new compounds
US4256735A (en) * 1979-01-29 1981-03-17 Merck & Co., Inc. Immunologically active dipeptidyl saccharides and methods of preparation
FR2449697A1 (fr) * 1979-02-20 1980-09-19 Anvar Nouveaux muramyl-peptides substitues sur un azote peptidique et medicaments les contenant
CA1185237A (en) * 1979-02-28 1985-04-09 Yuichi Yamamura 6-deoxyglucosamine-peptide derivatives, their production and use
FR2482957A2 (fr) * 1979-06-29 1981-11-27 Rhone Poulenc Ind Nouveaux dipeptides, leur preparation et les medicaments qui les contiennent
US4406889A (en) * 1980-02-15 1983-09-27 Ciba-Geigy Corporation Derivatives of aldohexoses, intermediates, processes for their manufacture, preparations containing such compounds, and their use
US4368190A (en) * 1980-04-17 1983-01-11 Merck & Co., Inc. Immunologically active dipeptidyl 4-O-,6-O-acyl-2-amino-2-deoxy-D-glucose derivatives and methods for their preparation
JPS6042398A (ja) * 1983-08-18 1985-03-06 Toshiyuki Hamaoka ムラミルジペプチド活性エステル誘導体
US4777160A (en) * 1986-09-18 1988-10-11 Bristol-Myers BU-2867T peptide antibiotics
EP3387005B1 (en) * 2015-12-10 2022-08-24 Bharat Biotech International Limited Novel muramyl peptide derivative compound, synthesis and uses thereof
CN108883080B (zh) * 2015-12-15 2021-12-21 巴拉特生物技术国际有限公司 胞壁酰肽衍生物化合物、其合成及其用途

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH613709A5 (en) * 1975-12-10 1979-10-15 Ciba Geigy Ag Process for the preparation of glucosamine derivatives

Also Published As

Publication number Publication date
SE7704609L (sv) 1977-10-27
JPH0371440B2 (es) 1991-11-13
DE2718010A1 (de) 1977-11-10
FR2349600B1 (es) 1981-01-02
NL7704555A (nl) 1977-10-28
JPS52131526A (en) 1977-11-04
JPH02138290A (ja) 1990-05-28
GB1571133A (en) 1980-07-09
FR2349600A1 (fr) 1977-11-25
SE445924B (sv) 1986-07-28
DE2718010C2 (es) 1990-11-08
CH636887A5 (en) 1983-06-30
JPS638119B2 (es) 1988-02-19

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